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Name : Mkms_2657 (Mkms_2657) Accession : YP_938642.1 Strain : Mycobacterium sp. KMS Genome accession: NC_008705 Putative virulence/resistance : Virulence Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.8 Position : 2788424 - 2789926 bp Length : 1503 bp Strand : - Note : KEGG: mmc:Mmcs_2613 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase DNA sequence : GTGACCGCGAACCGTCGGCCCGAGGGTGTACCGCAGCGCATCCAGCACTTCATCGGCGGGAAGTTGGTCGACAGCCTTGC CGACACGTGGTTCGACGTCATCGATCCGGTGACCAACCAGCCGTACGCGCAGGCCGCCGCAGGACAGGCCGACGATGTCG ACCGCGCGGTGGCCGCGGCCAAAGTCGCCTTCCGGACCGGGCCCTGGCCGAACATGCAGGCCCGGAGCCGTTCCCGGGTG CTGAACAGAATCGCGGACGCCATCGAGAGCCGCGATGCGCGGCTGGCCGAGTTGGAGTCGTTCGACAGCGGCCTGCCGAT CACGCAGGCGCTCGGCCAGGCCCGCCGCGCCGCCGAGAACTTCCGCTTCTTCGCCGACCTGGTGGTGGCGCAGGCCGACG ACGCCTACAAGGTGCCCGGCAGCCAGATCAACTACGTCAACCGCAAACCAAAAGGTGTCGCCGGCCTGATCACGCCATGG AACACCCCGTTCATGCTGGAGAGCTGGAAGTTGGCGCCGGCCTTGGCATCCGGATGCACCGTCGTATTAAAACCCGCCGA ATTCACTCCGCTGTCCGCTGGACTGTGGGCCGACATCTTCCGCGACGCGGGCGTTCCCGATGGGGTGTTCAACTTGGTCA ACGGCATTGGCGAAGAAGCCGGCGACGCGTTGGTCAAGCATCCCGACGTCAGAGTCATCTCCTTCACCGGTGAGTCGGCC ACCGGCGAGATCATCTTCCGCAACTGCGCCACCGGCCTCAAAGGCATGTCGATGGAACTCGGCGGCAAATCACCGGCGGT GGTGTTCGCCGATGCCGACCTCGACGCCGCCCTGGACTCCACGCTGTTCGGTGTCTTCTCACTCAACGGCGAGCGATGCA CGGCGGGCAGCCGCATCCTCGTCGAAGAGGAGATCTACGACGAATTCGTCGAACGGTTTGCCGCGCGGGCGGCCGGCATT GTGGTCGGGGATCCCCAGGATCCACGGACCGAGGTGGGTGCCCTGGTCCATCCTGAGCATTTCGCCAAAGTGATGTCCTA CATCGACGTCGGCAAGACAGAGGGACGGCTGCTGTGTGGGGGTGGGCGGCCGGCGCATCTGCCGCAGGGCAACTTCGTGG CGCCGACGGCCTTCGCCGATGTGGAGCCGAACGCGCGGATCTTTCAGGAGGAGATCTTCGGACCGGTGGTCGCGCTGTCG CGATTCCAGACCGAAGAGCAGGCGCTCGCGTTGGCTAATGGCGTGAAATACGGTCTGGCTGCTTACATCTGGACCAACGA CCTCAAACGTGCCCACCGGTTCGCGCAGAATGTCGACAGCGGCATGGTGTGGGTCAACTCCCACAACGTTCGCGATCTGC GCACCCCCTTCGGCGGAGTCAAGGCCTCGGGCCTTGGCCACGAAGGTGGCTACCGGTCCCTGGACTTCTACACCGACCAG CAGGCTGTGCACATCACCCTCGGCGACGTCCACACACCGAGATTCGGCATCACCGCCCGCTGA Protein sequence : MTANRRPEGVPQRIQHFIGGKLVDSLADTWFDVIDPVTNQPYAQAAAGQADDVDRAVAAAKVAFRTGPWPNMQARSRSRV LNRIADAIESRDARLAELESFDSGLPITQALGQARRAAENFRFFADLVVAQADDAYKVPGSQINYVNRKPKGVAGLITPW NTPFMLESWKLAPALASGCTVVLKPAEFTPLSAGLWADIFRDAGVPDGVFNLVNGIGEEAGDALVKHPDVRVISFTGESA TGEIIFRNCATGLKGMSMELGGKSPAVVFADADLDAALDSTLFGVFSLNGERCTAGSRILVEEEIYDEFVERFAARAAGI VVGDPQDPRTEVGALVHPEHFAKVMSYIDVGKTEGRLLCGGGRPAHLPQGNFVAPTAFADVEPNARIFQEEIFGPVVALS RFQTEEQALALANGVKYGLAAYIWTNDLKRAHRFAQNVDSGMVWVNSHNVRDLRTPFGGVKASGLGHEGGYRSLDFYTDQ QAVHITLGDVHTPRFGITAR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 7e-93 | 49 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-64 | 41 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-64 | 41 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-64 | 41 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-64 | 41 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 3e-64 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Mkms_2657 | YP_938642.1 | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase | VFG0082 | Protein | 8e-65 | 41 |
