Gene Information

Name : nrdF (Mkms_1875)
Accession : YP_937865.1
Strain : Mycobacterium sp. KMS
Genome accession: NC_008705
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1989112 - 1990074 bp
Length : 963 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAGCTGATTGACCGCGTCTCGGCGATCAACTGGAACCGTCTGCAGGACGACAAGGACGCCGAGGTGTGGGACCGGCT
CACGGGCAACTTCTGGCTGCCCGAGAAGGTGCCGGTGTCCAATGACATCCCGTCCTGGAACACGCTGACCGCCCACGAGA
AGCAGCTCACGATGCGGGTGTTCACCGGTCTGACGCTGCTGGACACCATCCAGGGCACCGTCGGCGCGGTCAGCCTCATC
CCCGACGCGCTCACCCCGCACGAGGAGGCGGTGTACACCAACATCGCGTTCATGGAGTCGGTGCACGCCCGCAGCTACAG
CAACATCTTCTCCACGCTGTGCTCGACGGCCGAGATCGACGATGCGTTCCGCTGGTCGGAGGAGAACCCGAACCTGCAGC
GCAAGGCCGAGATCGTCATGCAGTACTACAAGGGTGACGAACCGCTCAAGCGCAAGGTCGCCTCGACGCTGCTGGAGAGC
TTCCTGTTCTACTCGGGTTTCTACCTGCCGATGTACTGGAGCAGCCGCGCCAAGCTGACCAACACCGCCGACATGATCCG
GCTGATCATCCGCGACGAGGCCGTGCACGGCTACTACATCGGCTACAAGTTCCAGAAGGGACTGGCGCTGCAGGATCCCG
CGACCCAGGCCGAGCTCAAGGACTACACCTACGAGCTGCTCTTCGAGCTGTACGACAACGAGGTCGAATACACCCAGGAC
CTCTACGACAGCGTCGGCCTGACCGAGGACGTCAAGAAGTTCCTGCGCTACAACGCCAACAAGGCCTTGATGAACCTCGG
GTACGAGGCGCTGTTCCCGCGCGACGAGACCGACGTCAACCCGGCGATCCTGTCCGCACTGAGCCCCAACGCCGACGAGA
ATCACGACTTCTTCTCCGGTTCGGGGTCGAGCTACGTGATCGGCAAGGCCGTGGTCACCGAGGACGAGGACTGGGACTTC
TAG

Protein sequence :
MKLIDRVSAINWNRLQDDKDAEVWDRLTGNFWLPEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLI
PDALTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQRKAEIVMQYYKGDEPLKRKVASTLLES
FLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQKGLALQDPATQAELKDYTYELLFELYDNEVEYTQD
LYDSVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-113 75