Gene Information

Name : dnaB (azo0722)
Accession : YP_932226.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Unknown
Product : DnaB protein
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 768968 - 770377 bp
Length : 1410 bp
Strand : +
Note : Replicative DNA helicase (EC 3.6.1.-). PARTICIPATES IN INITIATION AND ELONGATION DURING CHROMOSOME REPLICATION; IT EXHIBITS DNA-DEPENDENT ATPASE ACTIVITY AND CONTAINS DISTINCT ACTIVE SITES FOR ATP BINDING DNA BINDING AND INTERACTION WITH DNAC PROTEIN PRIM

DNA sequence :
ATGAGTAGTACTTCCCGCCGGTTTCAGGATGGACCGCATGATCCCGAAATGGCCTCGATCAAGCTTCCTCCGCATTCGCT
GGAGGCCGAGCAGTCACTGATCGGTGGCATCCTGATCGACAACGCGGCCTGGGAGCGCATCGCCGACCTGGTGAACGAGG
CGGACTTCTACCGCGACGATCATCGCCGCATCTACCGCCATATCACCCGCCTCATTGACCTCGGCAAGCCGGCCGACGTC
GTCACTGTTTTCGAATCGCTCGAGAAGAACGGCGAAGCGGAGCAGGCTGGCGGACTGGTGTATCTGGCAGAGATCGCCAA
CAACACGCCGTCGGCGGCGAACATCCGGCGCTACGCCGAAATCGTTCGGGAGCGCGCGATCCTGCGTAAGCTGGTCGCGG
TGGGCGACGAGATCGCGGCGTCCGCGCTGACGCCCTCGGGCAAGGACGCCAAGTCGCTGCTCGATGAGGCGGAGGCGAAG
GTATTCGAGATCGCAGAGGCGGGGGCCCGTCACGCAAGCGGTTTCATTTCGATCCAGCCCATCCTGAAGCAGGTGGTCGA
CCGCGTGCAGGAGCTGTACGACCGCGACAGCCCCTCGGAGGTAACGGGTATTCCGTCCGGTTTCGTCGATCTCGACGACA
AGACGTCCGGCCTGCAGCCGTCGGATATGTTGATCGTCGCCGGGCGGCCGGCCATGGGCAAGACGACGTTTGCGCTTAAC
GTGGCTGAACACGTCGCGGTGGAAGCCCGTTTGCCGGTAGCGATCTTCTCGATGGAAATGCCCGGCACCCAGCTTGCGAC
CCGCTTCATCTCGTCGGTCGGCCGTATCGACATGCAGAAGATCCGCAGCGGGCGGCTCACCGACGAGGACTGGCAGCGCC
TCACCGTTGCAATGGGAAAGCTGTACGACGCGCCGCTCTATATTGATGAAACGCCCGGCCTGAATCCGATTGACCTGCGC
GCACGTGCGCGCCGGCTTGCCCGACAGTGCGGCAAGCTGGGGCTGATCGTGATCGACTACCTGCAGCTGATGACGGGGAG
CAAGGATAGCGATAACCGTGCCGCCGAGCTTTCCGAGATTTCCCGCTCGATCAAGGCGCTGGCAAAAGAGCTGCACGTTC
CTATCATTGCCCTGTCGCAGCTGAATCGAAGCCTGGAACAACGGCCGAACAAACGCCCCGTGATGTCCGACTTGCGTGAG
TCGGGTGCAATTGAGCAGGACGCGGACATCATCATGTTCATTTACCGGGATGAGGTTTACAACCCTGATTCGCCGGACAA
GGGAACTGCAGAGCTGATTATCGGCAAGCACCGTAATGGCCCGACGGGTGTGATTCGCATGACCTTCCTGGGCCAATACA
CGCGCTTCGAGAATTTCGCCGGCGGCGGCTTCTACACAGCGGATGAGTAA

Protein sequence :
MSSTSRRFQDGPHDPEMASIKLPPHSLEAEQSLIGGILIDNAAWERIADLVNEADFYRDDHRRIYRHITRLIDLGKPADV
VTVFESLEKNGEAEQAGGLVYLAEIANNTPSAANIRRYAEIVRERAILRKLVAVGDEIAASALTPSGKDAKSLLDEAEAK
VFEIAEAGARHASGFISIQPILKQVVDRVQELYDRDSPSEVTGIPSGFVDLDDKTSGLQPSDMLIVAGRPAMGKTTFALN
VAEHVAVEARLPVAIFSMEMPGTQLATRFISSVGRIDMQKIRSGRLTDEDWQRLTVAMGKLYDAPLYIDETPGLNPIDLR
ARARRLARQCGKLGLIVIDYLQLMTGSKDSDNRAAELSEISRSIKALAKELHVPIIALSQLNRSLEQRPNKRPVMSDLRE
SGAIEQDADIIMFIYRDEVYNPDSPDKGTAELIIGKHRNGPTGVIRMTFLGQYTRFENFAGGGFYTADE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-96 48
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 4e-91 46
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 8e-92 46
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-83 46
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 6e-84 46
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 2e-81 45
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 6e-83 44
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 6e-83 44
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 8e-72 43