Name : folA (azo3198) Accession : YP_934700.1 Strain : Azoarcus sp. BH72 Genome accession: NC_008702 Putative virulence/resistance : Resistance Product : FolA protein Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 3519505 - 3519999 bp Length : 495 bp Strand : + Note : Dihydrofolate reductase. catalytic activity: 5,6,7,8-tetrahydrofolate + nadp(+) = 7,8- dihydrofolate + nadph. pathway: essential step for de novo glycine and purine synthesis, dna precursor synthesis, and for the conversion of dump to dtmp. Pfam: Dihydrof DNA sequence : ATGACGACTCCACGCTCCCTCACCTTCGTCGTCGCGATCGCCTCCAACGGCGTGATCGGCCGAAACAACGCGCTGCCCTG GCGGCTGAAGGCCGACCTGGCGCACTTCAAGGCTGTCACCCTGGGTCACCCGATCGTGATGGGTCGCAAGACCTGGGAAT CGCTCGGCCGCCCATTGCCGGGTCGGCGCAACATGGTGGTCACGCGCAACGCGGATTACCGGGCGATCGGCGCGGAGGTC TTTGCGACGCCGGAGGCCGCGGTTAATGCGGTGGCGGAGGGCCCCCTGTTCGTGATCGGAGGCGCCCAGTTGTACAAGGA ACTGCTGCCGATGGCTGACCGGCTGCTGATCACCGAGGTCCTCGCCGACGTAGAAGGCGATGCCTACTTTCCGCCCTTCA ACCTCGACACATTCCGCGAATGCAGCCGCGAACACCACCCCGCGGATGCCGACAACCAATTCGCGTTCGACATCGTCGAC TACCGCCGCCGCTAA Protein sequence : MTTPRSLTFVVAIASNGVIGRNNALPWRLKADLAHFKAVTLGHPIVMGRKTWESLGRPLPGRRNMVVTRNADYRAIGAEV FATPEAAVNAVAEGPLFVIGGAQLYKELLPMADRLLITEVLADVEGDAYFPPFNLDTFRECSREHHPADADNQFAFDIVD YRRR |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
dfrA12 | ACF06156.1 | dihydrofolate reductase | Not tested | Tn5036-like | Protein | 1e-20 | 41 |