Gene Information

Name : folA (azo3198)
Accession : YP_934700.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Resistance
Product : FolA protein
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 3519505 - 3519999 bp
Length : 495 bp
Strand : +
Note : Dihydrofolate reductase. catalytic activity: 5,6,7,8-tetrahydrofolate + nadp(+) = 7,8- dihydrofolate + nadph. pathway: essential step for de novo glycine and purine synthesis, dna precursor synthesis, and for the conversion of dump to dtmp. Pfam: Dihydrof

DNA sequence :
ATGACGACTCCACGCTCCCTCACCTTCGTCGTCGCGATCGCCTCCAACGGCGTGATCGGCCGAAACAACGCGCTGCCCTG
GCGGCTGAAGGCCGACCTGGCGCACTTCAAGGCTGTCACCCTGGGTCACCCGATCGTGATGGGTCGCAAGACCTGGGAAT
CGCTCGGCCGCCCATTGCCGGGTCGGCGCAACATGGTGGTCACGCGCAACGCGGATTACCGGGCGATCGGCGCGGAGGTC
TTTGCGACGCCGGAGGCCGCGGTTAATGCGGTGGCGGAGGGCCCCCTGTTCGTGATCGGAGGCGCCCAGTTGTACAAGGA
ACTGCTGCCGATGGCTGACCGGCTGCTGATCACCGAGGTCCTCGCCGACGTAGAAGGCGATGCCTACTTTCCGCCCTTCA
ACCTCGACACATTCCGCGAATGCAGCCGCGAACACCACCCCGCGGATGCCGACAACCAATTCGCGTTCGACATCGTCGAC
TACCGCCGCCGCTAA

Protein sequence :
MTTPRSLTFVVAIASNGVIGRNNALPWRLKADLAHFKAVTLGHPIVMGRKTWESLGRPLPGRRNMVVTRNADYRAIGAEV
FATPEAAVNAVAEGPLFVIGGAQLYKELLPMADRLLITEVLADVEGDAYFPPFNLDTFRECSREHHPADADNQFAFDIVD
YRRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 1e-20 41