Gene Information

Name : aldA (azo2939)
Accession : YP_934442.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3223255 - 3224775 bp
Length : 1521 bp
Strand : -
Note : Aldehyde dehydrogenase (NAD+). Homology to aldA of X. autotrophicus of 76% (trembl|O50203). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase fam

DNA sequence :
ATGATTTACGAGATGCCCGGCAAGGCAGGCGCCAAAGTCCAGTTCAAGAGCCGCTACGACAACTTCATCGGCGGCAAGTG
GGTTGCGCCGGTCCGTGGCCAGTACATGGACAACATCACGCCGATTACCGGCAAGCCCTTCTGCCAGGTGGCCCGTTCGA
CCGAGGAAGACATCAACCTCGCGCTCGATGCCGCCCACGCCGCCGCCGACAAGTGGGGCCGCACCTCGGTCATCGAGCGC
GCCAACACGCTGTGCCGCATCGCCGACCGCCTGGAACAGAACCTCGAACTGATCGCCTACGCCGAGACCGTCGATAACGG
CAAGCCGATCCGCGAGACCATGGCCGCCGACATCCCGCTGGCCATCGATCACTTCCGCTACTTCGCCGGCTGCATCCGCG
CCCAGGAAGGCTCGCTCGCCGAACTCGACGAGAACACCGTCGCCTACCACTTCCACGAGCCGCTGGGCGTTGTCGGCCAG
ATCATTCCGTGGAACTTCCCGATCCTGATGGCGGCATGGAAGCTGGCGCCGGCGTTGGCCGCGGGCAACGTGGTGGTGCT
GAAGCCCGCCGAATCGACCCCGGTCGGCATCCTGGTGATCGCAGAACTGATCGCCGACCTGCTGCCCGCCGGCGTGCTCA
ACATCGTCAATGGCCTCGGCCGCGAAGCCGGCGTGCCGCTGGCCACCAGCAGCCGCATCGCCAAGATCGCCTTCACCGGC
TCCACCACCACCGGCCGCCTGATCATGCAGGCCGCGTCGCAGAACATCATCCCGGTGACGCTGGAACTGGGCGGCAAGTC
GCCCAACATCTTCTTCCAGGACGTGGCCGCGGCCGACGACGAGTTTTTCGACAAGGCGGTGGAAGGCTTCGTGCTGTTCG
CGCTCAACCAGGGTGAAGTGTGCACCTGCCCGTCGCGCGCGCTGATCCACGAATCCATCTACGACCGTTTCATGGACCGC
GCGCTGGCCCGCGTCAAGGCGATCAAGCAGGGCAACCCGCTCGACACCGAGACCATGATCGGCGCCCAGGCCTCCACCGA
GCAGATGAAGAAGATCCTGTCCTACATCGAACTCGGCAAGGAAGAAGGCGCGCAGCTGCTGGCCGGTGGCGGCGAAGCCA
AGTTCGGCGGCGAACTCGCCGAGGGCTACTACGTCCAGCCGACGGTGTTCAAGGGCCACAACAAGATGCGCATCTTCCAG
GAGGAAATCTTCGGGCCGGTGCTGTCGGTGACCACCTTCAAGGACGAGGCCGAGGCGCTCTCCATCGCCAACGACACGCT
GTACGGCCTGGGCGCCGGCGTGTGGTCGCGCGACGGCTCCACCGCCTACCGCATGGGCCGCAACATCAAGGCCGGCCGCG
TGTGGACCAACTGCTACCACCTGTACCCGGCGCACGCCGCGTTCGGTGGCTACAAGCAGTCCGGCATCGGCCGCGAAACC
CACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACAGCCCGAAGGCGCTCGGCTTCTTCTG
A

Protein sequence :
MIYEMPGKAGAKVQFKSRYDNFIGGKWVAPVRGQYMDNITPITGKPFCQVARSTEEDINLALDAAHAAADKWGRTSVIER
ANTLCRIADRLEQNLELIAYAETVDNGKPIRETMAADIPLAIDHFRYFAGCIRAQEGSLAELDENTVAYHFHEPLGVVGQ
IIPWNFPILMAAWKLAPALAAGNVVVLKPAESTPVGILVIAELIADLLPAGVLNIVNGLGREAGVPLATSSRIAKIAFTG
STTTGRLIMQAASQNIIPVTLELGGKSPNIFFQDVAAADDEFFDKAVEGFVLFALNQGEVCTCPSRALIHESIYDRFMDR
ALARVKAIKQGNPLDTETMIGAQASTEQMKKILSYIELGKEEGAQLLAGGGEAKFGGELAEGYYVQPTVFKGHNKMRIFQ
EEIFGPVLSVTTFKDEAEALSIANDTLYGLGAGVWSRDGSTAYRMGRNIKAGRVWTNCYHLYPAHAAFGGYKQSGIGRET
HKMMLDHYQQTKNLLVSYSPKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-133 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-143 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-143 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-143 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-142 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 6e-56 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_934442.1 aldehyde dehydrogenase VFG0082 Protein 1e-133 64