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Name : thmS1 (azo2250) Accession : YP_933754.1 Strain : Azoarcus sp. BH72 Genome accession: NC_008702 Putative virulence/resistance : Virulence Product : succinate semialdehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.16 Position : 2465256 - 2466758 bp Length : 1503 bp Strand : - Note : probable succinate semialdehyde dehydrogenase [NAD(P)+). Homology to thmS of Pseudonocardia sp. K1 of 55% (trembl|Q9F3V7). Is capable of oxidizing substrates using NADP as cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydr DNA sequence : GTGACCCTGTACCCCGACCAACTCATCAGCCCCGCCACCCGCGCCTTCCTCGCCCGCCCCAAACGTATGCTGATCGGCGC CGAATGGTCCGCCGCCGTCAGCGGTGAAACCCTGGCGGTGCTCGATCCGGCGACCGGGCAGGCTTTCGCCACGGTGCCGG CTGGCGGTGCCGCCGACATCGACCGCGCGGTGGCCGCTGCCCGCCGTGCCTTCGAATCCGGCGAGTGGCCGAAGATGCGG CCGGTGGACCGCGAGCGCCTGCTGCTCAAGTTCGCCGACCTGATCGAAGCCAACGCCCAGGAACTCGCCGAGATCGAGGC GCTGGACAACGGCAAGCCGGTGATGATGGCGCGCCATGTGGATGTGGCGCTGGTGGTCGATTTCCTGCGCTACATGGCGG GCTGGGCGACCAAGATCGAAGGCTCGACGATGGACGTGTCGGTGCCGCTGATGCGCGACCGCGAACTCTTCGGCTTTACC CGCCGCGAGCCGGTGGGCGTGGTCGGCGCCATCATCCCGTGGAATTTCCCGCTGCTGATGGCGGCGTGGAAGGTTGGCCC GGCGCTGACCTCCGGCTGCACCATGGTGTTGAAGCCGGCCGAAGAAACGCCGCTCACCGCGTTGCGCTTCGCCGAACTCG CGCTGGAAGCCGGCTACCCGGCCGGCGTGCTCAACGTCGTCACTGGCCACGGCGACACCGCCGGCGCGGCGCTCGCCAGC CACAAGGGCATCGAGAAGGTGGCCTTCACCGGCTCCACCGAGATCGGCAAGCTGGTCGGCAAGGCGGCGATCGACAACAT GACGCGGGTGTCGCTGGAACTGGGCGGCAAGAGCCCGGTGATCGTGCTCGACGATGCCGATCCCGCGATGGCCGCGGCCG GCGCGGCGCAGGCGATCTTCTTCAATCAGGGCCAGGTGTGCACCGCCGGCTCGCGGCTATTCATCCACAAGAGCCGCTTC GAGAAGGTGGTGGAGGGGCTGTCCGGCATTGCGGCGTCGATGAAGCTCGGGCCGGGCATCGATCCCTCCACCCAGATCGG TCCGCTGGTGTCGGCGGTGCAGCAGCAGCGCGTGCTCGGCTACATCGAGAGCGGGCTTGCGGAAGGCGCCAGGGCGGCCA CCGGCGGCGGAGCGGGCGGCGAGGCCGGCTACTTCGTCAAGCCGACGGTACTGGTGAACGCCCACGACGCGATGAAGGTG GTGCGCGAGGAGATCTTCGGCCCGGTGGTGGTGGCGATGCCCTACGAGGACCTCGATGAAGTTGCCCACCGCGCCAACGA CACGCCCTACGGCCTGGCGGCGAGCATCTGGTCCAACGACCTGACCCGGGTGCACCGGCTGATCCCCAAGATCAAGGCCG GCACCGTGTGGGTGAACTGCCACAACATCCTCGACAACGCGATGCCCTTCGGCGGTTACAAGCAGTCCGGTATCGGCCGC GAGATGGGCCGGGCGGTGCTCGACATGTACACCGAATCCAAGTCGGTGATCATGGCGCTCTAA Protein sequence : MTLYPDQLISPATRAFLARPKRMLIGAEWSAAVSGETLAVLDPATGQAFATVPAGGAADIDRAVAAARRAFESGEWPKMR PVDRERLLLKFADLIEANAQELAEIEALDNGKPVMMARHVDVALVVDFLRYMAGWATKIEGSTMDVSVPLMRDRELFGFT RREPVGVVGAIIPWNFPLLMAAWKVGPALTSGCTMVLKPAEETPLTALRFAELALEAGYPAGVLNVVTGHGDTAGAALAS HKGIEKVAFTGSTEIGKLVGKAAIDNMTRVSLELGGKSPVIVLDDADPAMAAAGAAQAIFFNQGQVCTAGSRLFIHKSRF EKVVEGLSGIAASMKLGPGIDPSTQIGPLVSAVQQQRVLGYIESGLAEGARAATGGGAGGEAGYFVKPTVLVNAHDAMKV VREEIFGPVVVAMPYEDLDEVAHRANDTPYGLAASIWSNDLTRVHRLIPKIKAGTVWVNCHNILDNAMPFGGYKQSGIGR EMGRAVLDMYTESKSVIMAL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 5e-77 | 46 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-74 | 43 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-76 | 42 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-76 | 42 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-76 | 42 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-76 | 42 |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 5e-63 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| thmS1 | YP_933754.1 | succinate semialdehyde dehydrogenase | VFG0082 | Protein | 6e-75 | 43 |
