Gene Information

Name : gabD1 (azo0222)
Accession : YP_931726.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Unknown
Product : succinate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.16
Position : 245317 - 246789 bp
Length : 1473 bp
Strand : +
Note : Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of R. eutropha of 68% (AAF19796). Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide

DNA sequence :
ATGCCTCTCACCCTCACCCGCCCCGACCTCCAGCGCCAGCACAACTTCATCGCCAACGCCTGGCACGACGCAACCGACGG
CCGCTTGCTGCCGGTCAGCGACCCGGCTACGGACACCGTGTTCGCCCACGTCCCCGACAGCGCCGCCGCCGATGCGCGCG
CCGCGGTCGATGCCGCCCATGCCGCCTTCCCGGCATGGCGCGCGCTCACCGGCCGCGAGCGCGCCCAGTACCTGAAGCGC
TGGCACGCGCTCATCCTCGCCTACCAGGACGACCTCGGCCGGCTGATCTCGCGCGAGCAGGGCAAGCCGCTGGCCGAAGG
CCGTGGGGAGGTGCTGTATGCCGCGAGCTATGTCGAGTGGTTCGCGGAGGAGGCGGCGCGCAGCCACGGCGAGGTCATTC
CCGAGCCGGTGCGCGGGCGCAAGATGCTGATGGTGAAGGAGCCGGTCGGTGTGGTCGCGGCGATCACGCCGTGGAATTTT
CCGGCGGCGATGATCGCCCGCAAGATCGCACCGGCGCTCGCCGCCGGCTGCACCGTGGTCGCCAAGCCGGCCGAGGACAC
GCCGCTGACCTCGCTGGCGCTGGTACGGCTGGCCGAAGAGGCCGGGCTGCCGGCAGGCGTGCTCAACATGGTCACCGCCT
CGCGCGAGCGTGCGGCCGAGGTGGTCGACGTGTGGCTGGCCGACAGCCGGGTGCGCAAGATCACCTTCACCGGCTCCACC
CCGGTGGGCAAGCACTTGGTGCGCGAATCGGCGGCCACGCTGAAGCGGGTGTCGATGGAGCTGGGCGGCAACGCGCCCTT
CATCGTGTTCGAGGATGCCGACCTCGACGCCGCGGTCGCCGGCCTGATGGCGGCCAAGTTCCGCAACGGCGGCCAGACCT
GCGTCTGCCCCAACCGGGTGTTCGTGCACGACGCGGTGCATTACGACTTCGTCGCCCGCCTGTCGGCGCGGGTGGCCGCG
CTCAAGGTCGGGCCGGCGAGCGCGCCGGACAGCCAGATCGGGCCGATGATCAACGCTCGCGCGGTGGACAAGATCGCCGC
CCACGTCGCCGACGCGGTGGAGCGGGGCGCCTGCGTCGTGACCGGCGGCGAGCGGCTCGCCGCGCTTGGCGCCAACTACT
TCGCGCCCACCATCCTGGTCGGGGTGGATGCCGGCATGCGTTGTACGCAGGAAGAAACCTTCGGTCCGGTGGTGCCGGTG
ACCCGCTTCGAGCATGAAGACGAGGTCGTTGCCGCCGCCAACGACACCCCGTTCGGGCTCGCCGCCTACTTCTACACCCG
CGACATGGCGCGCGCCTGGCGGGTGGCCGACCGGCTGGAAAGCGGCATCGTCGGCATCAACGAAGGCGCGCTCGCCGCCG
AGGTCGCGCCCTTCGGCGGCATCAAGGAGTCTGGCTACGGTCGAGAGGGCTCGCGCCATGGCCTGGACGACTACACGCAG
ATGAAGTACCTGTGCCAGGGCGGGCTGGGCTGA

Protein sequence :
MPLTLTRPDLQRQHNFIANAWHDATDGRLLPVSDPATDTVFAHVPDSAAADARAAVDAAHAAFPAWRALTGRERAQYLKR
WHALILAYQDDLGRLISREQGKPLAEGRGEVLYAASYVEWFAEEAARSHGEVIPEPVRGRKMLMVKEPVGVVAAITPWNF
PAAMIARKIAPALAAGCTVVAKPAEDTPLTSLALVRLAEEAGLPAGVLNMVTASRERAAEVVDVWLADSRVRKITFTGST
PVGKHLVRESAATLKRVSMELGGNAPFIVFEDADLDAAVAGLMAAKFRNGGQTCVCPNRVFVHDAVHYDFVARLSARVAA
LKVGPASAPDSQIGPMINARAVDKIAAHVADAVERGACVVTGGERLAALGANYFAPTILVGVDAGMRCTQEETFGPVVPV
TRFEHEDEVVAAANDTPFGLAAYFYTRDMARAWRVADRLESGIVGINEGALAAEVAPFGGIKESGYGREGSRHGLDDYTQ
MKYLCQGGLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 3e-126 55
cur_1509 YP_001800903.1 NAD-dependent aldehyde dehydrogenase Not tested Not named Protein 5e-79 41