Gene Information

Name : lapE (azo1853)
Accession : YP_933357.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Unknown
Product : 2-oxopent-4-enoate hydratase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3971
EC number : 4.2.1.80
Position : 2036713 - 2037510 bp
Length : 798 bp
Strand : +
Note : Conversion of 2-hydroxypent-2,4-dienoate into 4-hydroxy-2-oxopentanoate, involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. Belongs to the todj/xyli/xylj/hpcg family, TREMBL:Q93JW5 (62% identity); SWISSPROT:P23107 (58%

DNA sequence :
ATGAACGAGGAAAAGATCCAGCACTACGGCGACGCGCTCTACGAAGCGTGGCTGGCGCGCCGCACCATTCCGCCGCTGCT
CGAGCAGGAGCCGGACATCACCCTGGACGATGCCTACCGCATCCAGCGGCGCTACGTGGCGCGGCGGGTGCAGGCCGGCG
AGACCATCGTCGGCAAGAAGATCGGCGTGACCAGCAAGCCGGTGCAGGACTTCCTGGGCGTGTTCCAGCCGGATTTCGGC
CAGCTCACCTCGGGCATGGTCTATCAGGAAGGCGACACGTTGCCGCTGGATACGCTGATCCAGCCCAAGGCCGAGGCCGA
GCTGGCCTTTGTGCTGAAGGAAGACCTGCAGGGGCCGGGCGTGACGGCGATGGACGTGATCCGCGCCACCGACTACGTGG
TGCCCTGCTTCGAGATCGTCGACTCGCGCATTACGGACTGGAATATCCGCATCCAGGACACGGTGGCGGACAACGCCTCC
TGCGGGGTGTATGTGCTCGGCAAGACCAAGGGCGACCCGCGCAAGCTGGACATCACGCTGGCCGGCATGGTGCTGGAGAA
GAACGGCGAGCTGTTCTCCACCGGCGTTGGCGCCGCGGTGCAGGGTTCGCCTGCCAATGCGGTGGCCTGGTTGGCCAACA
CGCTGGGCGAGCTGGGGATTCCGTTCAAGGCCGGCGAGGTGATCTTGTCGGGTTCGCAGTCGGCGCTGGTGCCGGTGGCC
GATGGCGACGAACTGGTGTGCACCGTGGGCGGGCTTGGCAGCTGTCGGGTGAAGTTCGCGGGGAGGAGTGCGGTATGA

Protein sequence :
MNEEKIQHYGDALYEAWLARRTIPPLLEQEPDITLDDAYRIQRRYVARRVQAGETIVGKKIGVTSKPVQDFLGVFQPDFG
QLTSGMVYQEGDTLPLDTLIQPKAEAELAFVLKEDLQGPGVTAMDVIRATDYVVPCFEIVDSRITDWNIRIQDTVADNAS
CGVYVLGKTKGDPRKLDITLAGMVLEKNGELFSTGVGAAVQGSPANAVAWLANTLGELGIPFKAGEVILSGSQSALVPVA
DGDELVCTVGGLGSCRVKFAGRSAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaH AAO17184.1 HpaH Not tested tcd island Protein 3e-32 42