Gene Information

Name : lysS (azo1487)
Accession : YP_932991.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1624335 - 1625837 bp
Length : 1503 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCGACCATAACGCCACCCCTGCCGCCCAGGACGAAAACCACATCATCGCGGAGCGCCGCGAAAAACTCGCCCAATG
GCGCCAGGCAGGCCGGGCCTTCCCCAACGACTTCTCGCGCGAGAACACCGCCGGCAAGCTCGACGAGGTGTATGGCGACA
AAGAGCCGGAAGCGCTGGAAGCCAGCCCGGTGGAAGTCCGCGTAGCGGGCCGCGTGATGCTCAAGCGCGTGATGGGCAAG
GCCAGCTTCATCACCATCCAGGACCTCTCCGGCCGCATCCAGCTGTACGTGCAGCGCGACGGCGTCGGCGAAGACGTCTA
TGCCGACTTCAAGCACTGGGACATCGGCGACATCGTGGGCTGCGTCGGCACGCTGTTCAAGACCAAGACCGGCGAACTCA
CGGTCAAGGCGAGCGAAATCCGCCTGCTCACCAAGAGCCTGCGCCCGCTGCCGGACAAGTTCCACGGCCTCACCGACGTC
GAGCAGAAGTACCGCCAGCGCTACCTCGACCTGATCATGAGCGAGCAGACCCGCTTCACCTTCGTGGCCCGCAGCCGCAT
GGTGCAGTCGATCCGCAACTACATGATCAACCACGGCTTCCTCGAAGTCGAAACGCCGATGATGCACCCCATCCCCGGCG
GCGCCGCGGCCAAGCCCTTCGTCACCCACCACAACGCGCTCGACATGGAACTCTTCCTGCGCATCGCGCCGGAGCTGTAC
CTCAAGCGCCTGGTGGTCGGCGGGCTGGAGAAGGTGTTCGAGGTGAACCGCAACTTCCGCAACGAAGGCCTCTCGCCGCG
CCACAACCCCGAATTCACGATGATGGAGTTCTATGAGGCCTACGCGGACTACCGCAGCCTGATGAACTTCACCGAAGGCC
TCATCCGCCAGGCCGCACGCGAAGCGCTCGGCGCCGAAAGCTTCGTCTACCAGGGCCGCGAACTCGATCTCTCCAAGCCC
TTCCACCGCCTCACCATCGTGCAGGCCATCCGCAAGTACCACCCGGGCTTCTCCGAAGCCCAGCTGGCCGACGCGGAATG
GGTCAAGGAAAAGATCCAGGCCTTCGGCGAGAAGGTGAAGCCGGGCGGCCTCGGCAGCCTGCAGCTGCAACTCTTCGAAG
CCTGCGCCGAAGCCGAGCTGTGGGAACCGACCTTCATCATCGACTACCCGGTTGAAGTCTCGCCGCTCGCCCGCGCCTCC
GACAGCAACCCGGAAATCACCGAACGCTTCGAACTCTTCATCGTCGGCCGCGAGATCGCCAACGGCTTTTCCGAGCTCAA
CGACCCCGAAGACCAGGCCGCGCGCTTCCTCGCCCAGGCCCAGGCCAAGGAAGCCGGCGACGAAGAAGCGATGTACTACG
ACGCCGACTACATCCGCGCGCTCGAATTCGGCCTGCCGCCCACCGGCGGCTGCGGCATCGGCATCGACCGTCTGGTGATG
CTGCTGACCGACAGCGCCTCGATCCGCGACGTGATCCTGTTCCCGCAGATGCGTCCGGAATAA

Protein sequence :
MSDHNATPAAQDENHIIAERREKLAQWRQAGRAFPNDFSRENTAGKLDEVYGDKEPEALEASPVEVRVAGRVMLKRVMGK
ASFITIQDLSGRIQLYVQRDGVGEDVYADFKHWDIGDIVGCVGTLFKTKTGELTVKASEIRLLTKSLRPLPDKFHGLTDV
EQKYRQRYLDLIMSEQTRFTFVARSRMVQSIRNYMINHGFLEVETPMMHPIPGGAAAKPFVTHHNALDMELFLRIAPELY
LKRLVVGGLEKVFEVNRNFRNEGLSPRHNPEFTMMEFYEAYADYRSLMNFTEGLIRQAAREALGAESFVYQGRELDLSKP
FHRLTIVQAIRKYHPGFSEAQLADAEWVKEKIQAFGEKVKPGGLGSLQLQLFEACAEAELWEPTFIIDYPVEVSPLARAS
DSNPEITERFELFIVGREIANGFSELNDPEDQAARFLAQAQAKEAGDEEAMYYDADYIRALEFGLPPTGGCGIGIDRLVM
LLTDSASIRDVILFPQMRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-136 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_932991.1 lysyl-tRNA synthetase VFG1668 Protein 3e-136 56