Gene Information

Name : kdsB (azo1472)
Accession : YP_932976.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1603733 - 1604506 bp
Length : 774 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGTCCGCCTTCCGCATCGTCATTCCCGCCCGTTTCGCCTCCAGCCGGCTGCCGGGCAAGCCGCTCGCCGACATTGCCGG
CAAGCCGATGATCGTCCGCGTGCTCGAACGCGTGCAGGACGCCGGCGCCGCAGAGGTGTGGGTGGCCACCGACCACGATG
GCGTGCGCGAGGCGGTTGAGGCGGCCGGCGGCAAGGTGGTCATGACCCGCGCCGACCATCCCAGCGGCACCGATCGCCTC
GCCGAGGTCGCGTGCGCGCTCGGCTGGCAGGACGAGGACATCGTCGTCAACGTGCAGGGCGACGAGCCGCTGATCGACCC
CGCCATCATCACCGCGGTGGCGGCCGAACTCGCGGCCGACGGCGAAGCCGCCATCGCCACCGCGGCGCATCCGATCCACG
ACGCCGACGAAGTCTTCAACCCCAACGTCGTCAAGGTGGTGTGCGACGCCCGGCAGCGCGCGCTGTATTTCTCCCGCGCG
CCGATTCCCTGGGCCCGCGATGCCTGGGCGCAACCCGGCGAGCGCGCCGTCCTGCCGGCCGGACTTCCGGTGCTGCGCCA
TGTCGGGCTGTATGCCTACCGAGTCAGCTTCCTGCGCCGCTACACCGCGCTGGCGCCCGCGCCGATCGAGCAGTGGGAAG
CGCTGGAGCAGCTGCGGGCGATGTGGCACGGCTACCGCATCCGCGTGCTCGGGCTGCAGGCCGCGCCGGCCGCGGGGGTC
GATACCGTGGAAGACCTGGAGCGGGTGCGGGCGGTATTCGCCGGCGCTGCTTGA

Protein sequence : 
MSAFRIVIPARFASSRLPGKPLADIAGKPMIVRVLERVQDAGAAEVWVATDHDGVREAVEAAGGKVVMTRADHPSGTDRL
AEVACALGWQDEDIVVNVQGDEPLIDPAIITAVAAELAADGEAAIATAAHPIHDADEVFNPNVVKVVCDARQRALYFSRA
PIPWARDAWAQPGERAVLPAGLPVLRHVGLYAYRVSFLRRYTALAPAPIEQWEALEQLRAMWHGYRIRVLGLQAAPAAGV
DTVEDLERVRAVFAGAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 9e-42 52
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-41 51
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-41 51