Gene Information

Name : tpx (azo0105)
Accession : YP_931610.1
Strain : Azoarcus sp. BH72
Genome accession: NC_008702
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 123626 - 124126 bp
Length : 501 bp
Strand : +
Note : Probable thiol peroxidase. Homology to E. coli of 62% (sprot:TPX_ECOLI) Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity). Pfam: AhpC/TSA family no signal peptide no TMHs; High confidence in function and specificity

DNA sequence : 
ATGGCTACCGTCACCCTGGGCGGCAACCCGATTTCCATCGCCGGCCGCTTTCCGCAAGTGGGCGAAAGCGCACCGGCCTT
TGCGCTGACCACCCCGGAGCTGGCCGATGTCGGCCTCGACACCTGGGCCGGCAAGCGCAAGGTGCTCAACATCGTGCCCA
GCCTCGACACCCCGACCTGCGCGACCTCCACCCGGCGCTTCAACGCCGAGGCCGGCGCGCTGGCCAACACCGTGGTGCTG
GTGATCTCGGGCGACCTGCCCTTTGCCGCCAAGCGCTTCTGCGCGGCCGAGGGGCTCGACAACGTCAAGACGCTGTCGAC
CTTCCGCAACCCCGGTTTTGCCCGTGACTACGGCGTCGCGATCAGCTCCGGTCCGCTCGCCGGCCTCACCGCGCGCGCGG
TGGTCGTGGTCGACGAGAACGACAAGGTCATCCATGCCGAGCTGGTGTCGGAGATCAAGAACGAACCGGACTACGCCGCC
GCGCTCGCGGTGCTGAAGTAA

Protein sequence : 
MATVTLGGNPISIAGRFPQVGESAPAFALTTPELADVGLDTWAGKRKVLNIVPSLDTPTCATSTRRFNAEAGALANTVVL
VISGDLPFAAKRFCAAEGLDNVKTLSTFRNPGFARDYGVAISSGPLAGLTARAVVVVDENDKVIHAELVSEIKNEPDYAA
ALAVLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-34 45
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-34 45
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-34 45
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-34 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_931610.1 thiol peroxidase VFG0087 Protein 5e-35 45