Gene Information

Name : hemC (Pisl_0050)
Accession : YP_929577.1
Strain : Pyrobaculum islandicum DSM 4184
Genome accession: NC_008701
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 44350 - 45255 bp
Length : 906 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAGATCCGAGTTGCGACTAGGGGGTCGAAGCTCAGCCTTATCCAGACGGAGGAGCTCTTGGCGCAGATAAAGGCGGT
GGAGCCAGACGTCCAGTTCGAGATCGTGGTGGTGAAGACCACTGGCGACTTGATACAAGACAAGCCCCTCTTCCAGATAG
GGGTCAAGGGCATCTTCGAAAAAGAGGTGAACCTCGCCGTCTTGAGGGGCGAGGCTGACATGGCAGTACACAGTCTAAAG
GACCTCCCCTCTGAGCTCACCCCAGGCCTCGTCTTAGCTGGCTTCTCTAAGAGAGCTCCGCCGCATGACGTACTTATAAG
CCGCGGGGGCTACACGCTGGAGACTCTGCCGAAAGGCGCGGTGGTGGGGACCTCTAGCGTTAGGAGGGCAGAGTTTTTAA
AGGCTGTGAGACCTGACGTAGAAGTTAAACCCCTCCGGGGGAATGTAGATACAAGAGTGGGGAAGGTGTTGTCTGGTCAA
TACGACGCAGCTGTTATGGCAGCTGCGGGGCTCCAAAGGCTATATGGGAGCTCTCCCCCCGTCTCTATAGTGCCGCTCCG
CGTAGAGGAGGTGCCGCCGCCCCCCGGCCAAGGCATTGTCGTCGCTGTAGTGAAAGAGGAAGATAGCTGGCTGATAGACC
TTTTGAAAAAAGCTAGTGACAAAACTGCGGCAATTGAGGCAACTGCAGAGAGAGCCTTCTTGGCGGGGGTAGGCGCCGGC
TGCCACGTCGCAATCGGCGGCGTGGCGAAACTCACCCCCCAGGGGTCTCTGGAGTTTACCGCAGGATACGCCGCAGGCGG
AGCTAAATATGTGGTGAAGGTATTCGGAGAGGATCCCGTCGAGGTGGGGAAGAGGGCCGCACAGCTGATTGCCGAAGTGC
GTCAAAAATTTAAACAGAGAGACTAA

Protein sequence :
MKIRVATRGSKLSLIQTEELLAQIKAVEPDVQFEIVVVKTTGDLIQDKPLFQIGVKGIFEKEVNLAVLRGEADMAVHSLK
DLPSELTPGLVLAGFSKRAPPHDVLISRGGYTLETLPKGAVVGTSSVRRAEFLKAVRPDVEVKPLRGNVDTRVGKVLSGQ
YDAAVMAAAGLQRLYGSSPPVSIVPLRVEEVPPPPGQGIVVAVVKEEDSWLIDLLKKASDKTAAIEATAERAFLAGVGAG
CHVAIGGVAKLTPQGSLEFTAGYAAGGAKYVVKVFGEDPVEVGKRAAQLIAEVRQKFKQRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-30 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-30 42