Gene Information

Name : thyA (Sama_0867)
Accession : YP_926744.1
Strain : Shewanella amazonensis SB2B
Genome accession: NC_008700
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1058241 - 1059035 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGCAGTATCTCGACTTAATGAAGCACATCCTCGATAAGGGGACAGATAAAAGTGACAGAACCGGTACAGGCACCCG
TTCGGTTTTCGGTTATCAGATGCGCTTTGACCTCAATGAGGGGTTTCCGCTGGTTACCACCAAGAAGTGCCACCTGCGCT
CCATCATTCATGAACTGCTGTGGTTCCTGAAAGGTGAAACCAATGTGGATTATCTGCACGAAAACAAGGTGTCGATTTGG
GACGAGTGGGCCGATGAAAAGGGCAATCTGGGACCTGTCTATGGCGCCCAATGGCGCAGCTGGCCAACCCCTGATGGCCG
CCATATTGATCAGATTTCTCAAGTTATTGAGCAGATTAAAGCCACGCCGGACTCTCGCCGGTTAATCGTATCAGCCTGGA
ACGTGGGAGAGCTGGATAAAATGGCGCTGGCACCCTGCCATGCGTTTTTCCAATTTTACGTGGCCGATGGCAAACTGAGC
TGCCAGCTCTATCAGCGTTCCTGTGATGTGTTCCTGGGCCTGCCGTTTAATATTGCCAGTTATGCGCTGCTGACCATGAT
GGTGGCGCAGCAGTGTAATCTTGGCTTGGGCGATTTCGTTTGGACCGGTGGGGATACCCACCTCTACAGCAACCACATGG
AGCAGACTCAATTGCAGCTCTCACGGGAGCCTCGTCCTCTGCCCACCATGAAGATCCTCCGCCATCCAGAGTCGATTTTT
GATTACCGTTTCGAAGACTTTGAACTCAGTGGTTACGACCCCCATCCCCACATCAAGGCGCCCGTTGCTATCTAA

Protein sequence :
MKQYLDLMKHILDKGTDKSDRTGTGTRSVFGYQMRFDLNEGFPLVTTKKCHLRSIIHELLWFLKGETNVDYLHENKVSIW
DEWADEKGNLGPVYGAQWRSWPTPDGRHIDQISQVIEQIKATPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLTMMVAQQCNLGLGDFVWTGGDTHLYSNHMEQTQLQLSREPRPLPTMKILRHPESIF
DYRFEDFELSGYDPHPHIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-85 66
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-57 45