Gene Information

Name : cvrA; nhaP2; ycgO (Sama_0729)
Accession : YP_926607.1
Strain : Shewanella amazonensis SB2B
Genome accession: NC_008700
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 896674 - 898392 bp
Length : 1719 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGATTGCAGAAAACATGAATTTGTTGTTTTTGGTCGGCGCCTTGCTGGTGGGACTCAGTGTGGTGTTAAGCCCACTGTC
TTCGCGCTTGGGGGTACCCATATTGCTGGTATTCCTCGGCGTGGGGATCCTCGCCGGAGAGGATGGCCCCGGCGGTATAC
AATTCAACGATTATTCCACGGCCTATCTGGTGAGCAACCTGGCGCTGGCGGTTATCCTGTTGGATGGTGGCCTTCGAACC
AAGATGAGCAGCTTCAGGCTGGCGCTCTGGCCTTCGCTTTCCCTGGCGACACTTGGTGTGGCCATTACCACTGTATTAAC
CGGCTTGCTGGCTGCCTGGCTGTTCGACCTGAATTTGCTTATGGGGCTGCTGATTGGCGCCATTGTTGGCAGTACCGATG
CGGCTGCCGTGTTTTCGCTGCTTAAGGGCAGGGCACTGAACGAGCGCGTGGGTTCGACCCTTGAAATTGAGTCGGGCAGT
AACGACCCCATGGCCGTGTTTCTCACTGTTAGCCTGATTGCCATGATAGCCGCAGGCGGGAACTTTGATGGTCCCGGGCT
GATGCGCGACCTGGCGCTTCAGGCCGGTATGGGGTTGGCCGCGGGTTTTGGTGGTGGGTACCTGATATGGCATCTCGTCA
ATCGCAGCGTGTTGGCAGATGGGCTCTATCCCATTTTGGTGCTGGCGGGCGGCCTGTTGCTGTTTGCCCTGTCCAGTTTG
GCCGGTGGCAGCGGTATCCTGTCTATCTACCTCTATGGTCTGTTTCTTGGTAATCGTGGCATGCGCGGTAAGCACAGTAC
CCTGGCGGTGATGGACGGCCTGACCTGGTTGGCACAGATTGGCATGTTCCTGGTGCTGGGACTACTGCTGACGCCTTCAT
CATTGCTCGAGGTCCTGTTGCCCGGGTTGGTGCTGGCGCTGGGGATGATATTTATTGCCCGGCCACTGGCAGTGTGGATA
AGCCTGGCGCCCTTCAAGCGTTTTGTGGCGCGGGAGCGCTGGTTTATCAGTTGGGTGGGGCTCAGGGGAGCTGTGCCCAT
TATTCTGGCGGTATTCCCCATGATGGCCGGTCTACCCAATGCCGAGCTCTACTTCAACCTGGCCTTTTGTGTGGTGCTGG
TATCTTTACTGCTCCAGGGGTCTACCTTGCCGCTGGCGATGAAGCTCGCCAGGGTAGGGTTGCCGCCCAAGCCAGAGCCC
ATCAGCCGCGCGGGTGTCGACATCTTTCCAGCCAGCGAGTGGGAAATTTTTGTCTATCGCCTCAAACCCAATAAGTGGTG
TGTGGGCGAGCCCTTAAGGCGTTTGTCTATGCCGGAAGGAACCCGCATCGCGGCGCTGTTCAGGGAACATAATTTGCTGC
ACCCCTCGGGCAGTACCGAGCTTGCTGCCGACGATGTGCTGTGCGTGCTGGGCCAGGCCAAAGACTTGCCCGCCCTCAGT
CAGCTCTTCAGTGAGGCGCCGGAAAACCCTGCCATGGCAGGCTTTTTTGGTGACTTTATGTTGGCTACTTCGGTACGTCT
TGCGGATTTGGCGCCGCTTTATGGCTTTGGCCTGCATGAAGACGAAGTGGGGCTGACTCTGGAAGACCTGATGCACCAAA
AGCTGGGTCGCAACCCGGTAGAGGGTGACAGCTTTGAGTGGCAGGGCTGTGATTGGGTGGTGCGTACCATGGAAGGGGAT
TGTCCAACCTGCCTTGGTTTGAAGCTCAAGGCAGGCTGA

Protein sequence :
MIAENMNLLFLVGALLVGLSVVLSPLSSRLGVPILLVFLGVGILAGEDGPGGIQFNDYSTAYLVSNLALAVILLDGGLRT
KMSSFRLALWPSLSLATLGVAITTVLTGLLAAWLFDLNLLMGLLIGAIVGSTDAAAVFSLLKGRALNERVGSTLEIESGS
NDPMAVFLTVSLIAMIAAGGNFDGPGLMRDLALQAGMGLAAGFGGGYLIWHLVNRSVLADGLYPILVLAGGLLLFALSSL
AGGSGILSIYLYGLFLGNRGMRGKHSTLAVMDGLTWLAQIGMFLVLGLLLTPSSLLEVLLPGLVLALGMIFIARPLAVWI
SLAPFKRFVARERWFISWVGLRGAVPIILAVFPMMAGLPNAELYFNLAFCVVLVSLLLQGSTLPLAMKLARVGLPPKPEP
ISRAGVDIFPASEWEIFVYRLKPNKWCVGEPLRRLSMPEGTRIAALFREHNLLHPSGSTELAADDVLCVLGQAKDLPALS
QLFSEAPENPAMAGFFGDFMLATSVRLADLAPLYGFGLHEDEVGLTLEDLMHQKLGRNPVEGDSFEWQGCDWVVRTMEGD
CPTCLGLKLKAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 2e-99 60
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 2e-99 60