Gene Information

Name : guaA (Sama_2358)
Accession : YP_928232.1
Strain : Shewanella amazonensis SB2B
Genome accession: NC_008700
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2832531 - 2834108 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCAACATTCATGAGCACAAGATACTTATTCTGGATTTCGGCTCTCAGTACACTCAGCTGATCGCCCGCCGTATTCG
TGAAATCGGCGTGTACTGCGAACTCTGGGCCTGGGATGTGACCGAAGCGCAAATCCGTGAATTTGCCCCTAACGGTATTG
TTCTGGCCGGTGGTCCCGAGTCGGTAACCGAAGATAACTCTCCCCGCGCTCCCGAGTACGTGTTCGACGCCGGTGTGCCT
GTGCTGGGGATTTGCTACGGCATGCAGACCATGAGCGAGCAGCTGGGCGGTAAGGTTATTCAGGGTGTTGGCGAGCGTGA
GTTCGGTTATGCCCAGGTGGAAGTACTCACCGACAGCGCACTGCTGCGTCATATCGAAGACGGTATCTCTGATGCCGGCA
AGCCAGTGCTGGACGTATGGATGAGCCACGGCGACAAGGTGTCTGCCATTCCTGAAGGCTTTGTGGCCGTTGCCAAGACT
GAAACCTGTCCGTTTGCCGTGATGGCCAACGAAGACAAGAAGTTTTACGGCGTACAGTTCCACCCTGAAGTGACCCACAC
CCGTCAGGGCAAGCGCATGCTCGAACACTTTGTGATGGACATCTGTGGCTGTGACAACAAATGGCAGCCAGCCTCCATCA
TCGAAGACGCCGTTGAGCGCATCAAAGCCCAGGTGGGTGACGATGAAGTGATCCTCGGCCTCTCAGGCGGTGTGGATTCA
TCCGTGACTGCCATGCTGCTGCACCGTGCCATCGGCGAGCGCCTGACCTGTGTGTTCGTTGACAACGGCCTTTTGCGTCT
CAATGAAGCCAAGCAGGTACTGGAAATGTTCGGTGACCACTTTGGTCTCAACATCGTCCACGTGGATGCCGAAAACCGCT
TCCTCGAAGCGCTCAAGGGCGAAAACGACCCAGAAGCCAAGCGTAAGATCATTGGCCGCGTATTCGTGGAAATCTTCGAC
GAAGAAGCCTCCAAGTGTGTTAACGCCAAGTGGCTGGCTCAGGGCACCATTTACCCTGACGTGATTGAATCTGCAGGCAG
CGCCACCGGCAAGGCCCATGTGATCAAGTCACATCACAACGTGGGCGGTCTGCCGGATGACATGGAGCTGGGCTTGGTTG
AGCCACTGCGGGAACTCTTCAAAGACGAAGTACGTAAGATTGGTCTGGAACTCGGCCTGCCTTACGACATGCTCTATCGC
CACCCATTCCCAGGCCCGGGCCTTGGGGTGCGTGTACTGGGCGAAGTGAAGAAAGAGTACTGCGACCTTTTGCGCCGCGC
TGATGCCATCTTCATCGAAGAGCTGCACCGCGCCGATCTGTACAACAAGGTCAGCCAGGCGTTCACCGTGTTCCTGCCGG
TTCGCAGTGTGGGCGTGATGGGCGATGGCCGTAAGTACGACTGGGTTGTGTCGCTGCGCGCCGTCGAAACCATCGACTTT
ATGACTGCACACTGGGCGCACCTGCCATATGATTTCCTTGGCCGCGTTTCCAACCGCATCATCAACGAAGTCGACGGCAT
CTCCCGCGTGGTGTATGACATCTCCGGCAAGCCACCTGCCACCATCGAGTGGGAATAA

Protein sequence :
MSNIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIVLAGGPESVTEDNSPRAPEYVFDAGVP
VLGICYGMQTMSEQLGGKVIQGVGEREFGYAQVEVLTDSALLRHIEDGISDAGKPVLDVWMSHGDKVSAIPEGFVAVAKT
ETCPFAVMANEDKKFYGVQFHPEVTHTRQGKRMLEHFVMDICGCDNKWQPASIIEDAVERIKAQVGDDEVILGLSGGVDS
SVTAMLLHRAIGERLTCVFVDNGLLRLNEAKQVLEMFGDHFGLNIVHVDAENRFLEALKGENDPEAKRKIIGRVFVEIFD
EEASKCVNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHRADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-125 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-125 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-125 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-112 48