Gene Information

Name : Noca_0976 (Noca_0976)
Accession : YP_922185.1
Strain : Nocardioides sp. JS614
Genome accession: NC_008699
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1024210 - 1025373 bp
Length : 1164 bp
Strand : +
Note : PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tfu:Tfu_0440 cystathionine gamma-synthase

DNA sequence :
ATGAGCAGCCAGCAGCACCGGACCAAGTCCGGCTTCGAGACGCGTGCGATCCACGCGGGGTACGAGCCCGACGCCGCGAC
CGGAGCGGTCATCCCGCCGATCTACGCGACCAGCACCTTCAAGCAGGACGGGGTGGGCGGCCTGCGCGGCGGGTACGAGT
ACAGCCGCTCCGCCAACCCCACCCGCACCGCGCTCGAGGCGAACATCGCGGCGTTGGAGGAGGGGGAGCGCGGCTTCGCG
TTCGCCTCCGGCCTGGCGGCCGAGGACACCCTGGTGCGGGCGCTGTGCCGACCCGGTGACCACGTGGTGATCCCCGACGA
CGCGTACGGCGGCACCTTCCGCCTCTTCGACAAGGTCGAGCAGGTCTGGGGCCTGGCGCACAGCCCAGCGCCGGTCTCCG
ACGCAGAGGCGGTCGCCGCGGCGATCCGGCCCGGGGAGACGCGGCTCGTCTGGGTCGAGACCCCGACCAACCCGCTGCTG
AACATCGGCGACCTCGAGGCGCTCGCCGCCGTCGCCCACGACGCGGGGGCGCTGCTGGTCGTGGACAACACCTTCGCCTC
GCCGTACCTCCAGCAGCCGCTGACCCTGGGCGCGGACGTCGTCGTACACTCGACCACCAAGTACTGCGGCGGGCACTCCG
ACGTCGTCGGCGGCGCCCTCGTGGTCAAGGACCTCGACCTCGCCGAGCGGGTCGGCTTCCACCAGAACGCGATGGGCGCG
GTCGCGGGGCCCTTCGACGCCTGGCTGACCCTGCGCGGCCTGAAGACGCTCGCGCTGCGCATGGAGCGGCACTGCGACAA
CGCCGAGCGGGTCGTCGACTTCCTCACCAGCCACCCCGCGGTCGGCGACGTGATCTACCCCGGCCTGGAGACCCACCCCG
GCCACGAGGTCGCACAGCGGCAGATGCGCCGCTTCGGCGGCATGGTGTCCTTCCGCGTGCACGGCGGGGAGGAGCAGGCG
CTCGCGGTGTGCGACCGCACCGAGATCTTCACGCTGGGCGAGTCGCTCGGCGGCGTCGAGTCGCTGATCGAGCACCCCGG
CCGGATGACCCACGCCAGCGTCGCCGGCACCGACCTGGAGGTCCCGCCGGACCTGGTCCGGCTCAGCGTCGGCATCGAGA
CCGCCGATGACCTGGTCGCCGACCTCGAGCGCGCGCTTGGCTGA

Protein sequence :
MSSQQHRTKSGFETRAIHAGYEPDAATGAVIPPIYATSTFKQDGVGGLRGGYEYSRSANPTRTALEANIAALEEGERGFA
FASGLAAEDTLVRALCRPGDHVVIPDDAYGGTFRLFDKVEQVWGLAHSPAPVSDAEAVAAAIRPGETRLVWVETPTNPLL
NIGDLEALAAVAHDAGALLVVDNTFASPYLQQPLTLGADVVVHSTTKYCGGHSDVVGGALVVKDLDLAERVGFHQNAMGA
VAGPFDAWLTLRGLKTLALRMERHCDNAERVVDFLTSHPAVGDVIYPGLETHPGHEVAQRQMRRFGGMVSFRVHGGEEQA
LAVCDRTEIFTLGESLGGVESLIEHPGRMTHASVAGTDLEVPPDLVRLSVGIETADDLVADLERALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-69 46
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-68 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Noca_0976 YP_922185.1 cystathionine gamma-lyase BAC0207 Protein 3e-58 43