Gene Information

Name : Noca_0846 (Noca_0846)
Accession : YP_922056.1
Strain : Nocardioides sp. JS614
Genome accession: NC_008699
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 884902 - 886383 bp
Length : 1482 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: bxe:Bxe_A3599 betaine-aldehyde dehydrogenase

DNA sequence :
ATGACGACCACGACGGACGCTTCGGACCTGGCGGTCTACGACCTCTTCGTGGACGGCCGCTGGCAGCCCTCGCGGACCGG
GCGCACCTCGGAACGGACCAGTCCGGGCGACGGCCGGCTCGTCGGCCGCTACGCCCGCGGGGACGGGGCGGACGTGGACC
TCGCCGTCGCCGCCGCCCGGCGCGCCTTCGACGAGGGCCCCTGGCCGACCATCGACGCGACCAAGCGCGCTGCCATCATG
CGGCGCGCCGCGGACCTGCTGCGCGAGCGCGCCGACACCATCGGCCGGCGGATCGCGCTCGAGCTGGGCAAGCCGATCTC
GATGGCCCGCAACGAGGTCGTGCTGACCGCCGAGGTCTTCGACTACTACGCCGCCCTGGCCCTCGACCAGCGCGGTGAGC
TGATCTCCCAGCACACGGCCTCCGCCCTCGGCATGATCGTGAAGGAGCCGGTCGGCGTGGTCGGCATGATCACGCCCTGG
AACTTCCCGCTGCTGCTGCTCTCCTGGAAGGTGGCCCCGGCCCTCGCCGCCGGGTGCACGATGGTCGCGAAGCCGGCCAG
CCTGACCCCGGGGAGCACGCTGGATCTCGCCTCGGTGCTGGCGGACGCGGGTGTGCCCGACGGCGTCTACAACGTCGTCA
CCGGCGGCGGCGCCGAGGTCGGCGACGCGCTCGCCCAGCACCCGGGCATCGACAAGATCGCGTTCACCGGGTCCACCGAG
GTGGGCCAGACCGTGATGCGCGCGGCGGTCGGCACGGTCAAGAAGGTGAGCATGGAGCTGGGCGGCAAGTCGCCCAACAT
CGTGTTCGCCGACGCCGATCTCAAGCAGGCCGTGCGTGGTGCCTACTGGGGCATCTTCCTCAACAGCGGCCAGGCCTGCC
AGGCCGGCAGCCGATTGCTCGTCCAGCGCGAGGTCCACGAGGAGTTCGTCTCCTCGCTGGTGGAGATGGCACGGTCCAGC
AAGGTCGGGGATCCCCTCGACGAGGGCACCCAGATCGGGCCCATGGTCGACCAGGCGCAGCTCGACACGGTGCTCGACTA
CATCGGGAAGGGTCGGGAGGCGGGGGCGGCGCTGGTCGCCGGCGGGAACCGGCTCGGCGGAGAGCTGGCCGACGGCCTCT
ACGTCGAGCCGACCATCTTCGACAACGCCGCGCCCGACCACGCGATCTCCCGCGAGGAGATCTTCGGACCGGTCCTGGCA
GTCACGCCCTTCGACACCCTCGACGAGGCGGTCCGCCTGGCCAACGACTCGCCGTACGGCCTCGCGTCCGCGGTGTGGAG
CACGAACATCGACACCGCGATCAAGACGTCCAAGCGCCTGCGCGCCGGCACGGTGTGGATCAACGCCTACCACGATGCGG
GACTGCCGTTCTGCATGCCGATGGGCGGCTACAAGTCGAGCGGGATCGGGCGTGAGCTCGGCCGCGAAGGCCTGGCGCAG
TACTTCGAGACCAAGGCGATCCACCTGCGACTCGGGCGCTGA

Protein sequence :
MTTTTDASDLAVYDLFVDGRWQPSRTGRTSERTSPGDGRLVGRYARGDGADVDLAVAAARRAFDEGPWPTIDATKRAAIM
RRAADLLRERADTIGRRIALELGKPISMARNEVVLTAEVFDYYAALALDQRGELISQHTASALGMIVKEPVGVVGMITPW
NFPLLLLSWKVAPALAAGCTMVAKPASLTPGSTLDLASVLADAGVPDGVYNVVTGGGAEVGDALAQHPGIDKIAFTGSTE
VGQTVMRAAVGTVKKVSMELGGKSPNIVFADADLKQAVRGAYWGIFLNSGQACQAGSRLLVQREVHEEFVSSLVEMARSS
KVGDPLDEGTQIGPMVDQAQLDTVLDYIGKGREAGAALVAGGNRLGGELADGLYVEPTIFDNAAPDHAISREEIFGPVLA
VTPFDTLDEAVRLANDSPYGLASAVWSTNIDTAIKTSKRLRAGTVWINAYHDAGLPFCMPMGGYKSSGIGRELGREGLAQ
YFETKAIHLRLGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-75 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-71 43
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-74 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-74 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-74 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Noca_0846 YP_922056.1 aldehyde dehydrogenase VFG0082 Protein 7e-72 43