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Name : guaA (Noca_3631) Accession : YP_924818.1 Strain : Nocardioides sp. JS614 Genome accession: NC_008699 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 3849134 - 3850717 bp Length : 1584 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACGCAGCCCGCGGAGCACGATCTGGTCCTGGTGGTCGACTTCGGGGCGCAGTACGCCCAGCTGATCGCCCGGCGGGT CCGCGAGGCGCGGGTCTACTCCGAGATCGTGCCGCACACGACCCCGGTGGCCGAGATCCTGGCCCGCGAGCCGAAGGCGA TCATCCTCTCCGGCGGCCCGTCCTCGGTCTACGAGCCCGACGCCCCGAGCATCGACCCCGCGATCTTCACCTCCGGCACC CCGGTGTTCGGGATGTGCTACGGCTTCCAGCTGATGGCCCAGGGCCTCGGGGGCGAGGTGGCCCACACCGGCGCCCGGGA GTACGGGCGTACGGCGGTCGCCGTGGCCCGACCCGGGACGCTGCTGGCGGACATCCCCGCGCACCACACCGTGTGGATGT CGCACGGCGACTCGGTGGCGGCCGCCCCGTCCGGCTTCGACGTGCTGGCCTCGACGGCCACGACGCCGGTGGCGGCGTTC GAGGACGTCGACCGCGGCCTGGCCGGCGTCCAGTGGCACCCCGAGGTGCTGCACACCGAGCACGGCCAGAAGGTGCTCGA GCACTTCCTGGTCCAGATCGCCCACTGCCGCCAGACCTGGACCATGGTCAACATCGTCGAGGAGCAGATCGAGGCCATCC GCGCGCAGATCGGCGATCGCGGCCAGGCGATCTGCGGGCTGTCCGGCGGCGTCGACTCCGCGGTCGCGGCCGCGATCGTG CAGCGGGCGATCGGCGACCGGCTCACCTGTGTGTACGTCGACCACGGGCTGATGCGCCAGGGCGAGACCGAGCAGGTCGA GCGCGACTTCGTGGCCGCGACCGGCGTCGACCTCAAGGTCGTCGACGCCGAGAAGCAGTTCCTCGACGCACTCGCGGGCG TCACCGACCCCGAGGAGAAGCGCAAGATCATCGGCCGCGAGTTCATCCGGGTCTTCGAGGCCGCGGAGGCGGACATCCTC GGCGGGAGTCTGCCGGACGATGGGGGGAGCAAGGTCGCGTTCCTCGTCCAGGGCACGCTCTACCCCGACGTGGTCGAGTC CGGCGGGGGAGCGGGGACCTCCAACATCAAGTCACACCACAACGTCGGCGGCCTGCCCGACGACCTCGAGTTCGAGCTGG TCGAGCCGCTGCGCACCCTGTTCAAGGACGAGGTCCGGCTGGTCGGCGAGCAGCTCGGCCTGCCGGCCGAGATCGTGTGG CGCCAGCCGTTCCCGGGCCCCGGGCTCGGCATCCGGATCATCGGCGAGGTCACCCGCGAGCGGCTCGACATCCTCCGCGA GGCCGACGCCATCGCCCGGGAGGAGCTCACCCGCGCCGGCCTGGACCGCGACATCTGGCAGTTCCCCGTCGTGCTCCTCG CCGACGTCCGCTCGGTCGGCGTCCAGGGTGACCACCGCACCTACGGACACCCCGTCGTGCTCCGTCCGGTCACCTCCGAG GACGCGATGACCGCCGACTGGGCGCGGCTGCCGTACGACGTGCTCGAGCGGATCTCGACCCGGATCACCAACGAGGTGCG GGAGATCAACCGGGTGACGGTCGACATCACCTCCAAGCCCCCGGGCACCATCGAGTGGGAGTGA Protein sequence : MTQPAEHDLVLVVDFGAQYAQLIARRVREARVYSEIVPHTTPVAEILAREPKAIILSGGPSSVYEPDAPSIDPAIFTSGT PVFGMCYGFQLMAQGLGGEVAHTGAREYGRTAVAVARPGTLLADIPAHHTVWMSHGDSVAAAPSGFDVLASTATTPVAAF EDVDRGLAGVQWHPEVLHTEHGQKVLEHFLVQIAHCRQTWTMVNIVEEQIEAIRAQIGDRGQAICGLSGGVDSAVAAAIV QRAIGDRLTCVYVDHGLMRQGETEQVERDFVAATGVDLKVVDAEKQFLDALAGVTDPEEKRKIIGREFIRVFEAAEADIL GGSLPDDGGSKVAFLVQGTLYPDVVESGGGAGTSNIKSHHNVGGLPDDLEFELVEPLRTLFKDEVRLVGEQLGLPAEIVW RQPFPGPGLGIRIIGEVTRERLDILREADAIAREELTRAGLDRDIWQFPVVLLADVRSVGVQGDHRTYGHPVVLRPVTSE DAMTADWARLPYDVLERISTRITNEVREINRVTVDITSKPPGTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 1e-177 | 71 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-142 | 53 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-142 | 52 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 2e-142 | 52 |
