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Name : Noca_2312 (Noca_2312) Accession : YP_923504.1 Strain : Nocardioides sp. JS614 Genome accession: NC_008699 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 2462156 - 2462638 bp Length : 483 bp Strand : + Note : PFAM: dihydrofolate reductase region; KEGG: tbd:Tbd_2039 dihydrofolate reductase DNA sequence : ATGACCCCCGGCGGCAAGCGCGTCGTCCTCGTCGCCGCCGTGGCGCGCAACGGCGTGATCGGCGACGGCCCCGACATCCC CTGGCAGCTGCCCGGGGAGCAGCGGCTGTTCAAGGGCCTGACCTGGGGGCACATCCTGGTGATGGGCCGGGCGACCTACG ACTCGATCGGCCGGCCGCTGCCCGGGCGCACCACGATCGTGCTCACCCGGTCCCCGGACTGGTCGGCCGAGGGGGTGCAT GTCGCCCACGACCTGCCGGCGGCCCTCGCGCTCGCCGACACGCTCGAGGGCGAGGTGATGGTCGCCGGAGGCGGCCAGGT GTACGCCGCCGCGCTGCCGGTCGCCGACGAGCAGGTGCTCAGCGAGGTGGACCTGGAGCCGCAGGGCGACGCGTTCTACC CCGAGTTCGACCGCAGCGAGTGGCGCGAGACCGCCCGCGAGCAGCACGACGGGTACGACCGCGTGGTGCTTGTCCGGGCC TGA Protein sequence : MTPGGKRVVLVAAVARNGVIGDGPDIPWQLPGEQRLFKGLTWGHILVMGRATYDSIGRPLPGRTTIVLTRSPDWSAEGVH VAHDLPAALALADTLEGEVMVAGGGQVYAAALPVADEQVLSEVDLEPQGDAFYPEFDRSEWRETAREQHDGYDRVVLVRA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA12 | ACF06156.1 | dihydrofolate reductase | Not tested | Tn5036-like | Protein | 6e-26 | 48 |
| dfrA5 | AET25387.1 | dihydrofolate reductase | Not tested | PAGI-2(C) | Protein | 9e-18 | 45 |
| dfrA5 | AFG30110.1 | dihydrofolate reductase | Not tested | PAGI-2 | Protein | 9e-18 | 45 |
| unnamed | AEL12695.1 | DfrA5 | Not tested | AbaR21 | Protein | 4e-19 | 44 |
| dfrA1 | ADZ05803.1 | trimethoprim-insensitive dihydrofolate reductase | Not tested | AbaR3 | Protein | 4e-19 | 44 |
| dfrA15 | AGK07099.1 | DfrA15 dihydrofolate reductase | Not tested | SGI1 | Protein | 5e-18 | 43 |
