Gene Information

Name : Noca_0174 (Noca_0174)
Accession : YP_921406.1
Strain : Nocardioides sp. JS614
Genome accession: NC_008699
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 187506 - 188780 bp
Length : 1275 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCCCGTGTCCTCCGGGACGAGCCCGACCGCGTGCGCGCCGCCCAGGTCAAGCGCGGTCTGTCCGACGAGGT
CGTGGACCACGCGCTGTCCGCGGACGGCGAGCGTCGCCGGGCGATCGCCGCGTTCGAGGCCAAGCGGGCCGAGCAGAAGC
AGCTCGGCAAGCTGATCCCGCAGGCCCAGGGTGAGGAGAAGCAGGCGCTGCTGGCGCAGACCAAGACCCTCGCTGCCGAG
GTCAAGCAGGCCGAGGCGGCCCAGGCCGTGGCCGAGGAGGCCTGGCAGGCGGCCCTGATGAGCATCCCGAACCTCGCGGC
CGACGAGGCGCCCGCCGGCGGCGAGGACGACTACGTCGTGCTCGAGGAGATCGGCACCCCCCGCGACTTCGCGGCCGACG
GCTTCGAGCCGCGCGACCACATCGAGCTGGGCCGGATGCTCGGCGCGATCGACCTCGACCGGGGCGCCAAGGTGTCCGGG
TCGCGGTTCTACTTCCTCACCGGCGCCGGGGCCGAGCTCGAGCTGGCGCTGGTCAACCTGGCCATGCAGCAGGCCCGCGA
GTCCGGCTTCACCCCGGTCATCGCCCCCTCGATGGTCAAGCCGCGCGCGATGGACGGCACCGGGTTCCTCGGCCAGGCGG
CCGACGACGTCTACCGGATCGAGGGCCAGGACATGTACCTCGTCGGGACGTCCGAGGTCCCGATGGCGGCGTACCACTCC
GACGAGATCCTCGACGGCGGCGCGCTGCCGCTGCGCTACGCCGCGTTCAGCCCGTGCTTCCGCAAGGAGGCCGGCTCGCA
CGGCAAGGACACCAAGGGCATCATCCGGGTGCACTGGTTCGACAAGGTCGAGATGTTCGTCTACACCACGACCGAGGAGT
CGTACGCCGAGCACCAGCGGCTGCTGGCGTGGGAGAAGGAGTTCCTCGAGAAGCTCGAGCTCGCCTACCGGGTGATCGAC
GTCGCCGCCGGTGACTTGGGCCTGTCCGCGCAGCGGAAGTTCGACTGCGAGGCCTGGATCCCCACCCAGGGCCGCTACCG
CGAGCTCACCTCGACGTCGAACTGCACCGAGTTCCAGACCCGCCGCCTCGACACCCGCGGCCGGTTCGGGTCGGAGATCA
GGCCGATCTCGACCCTCAACGGCACCCTGTGCGCGATCACCCGCACGATCGTGGCGGTGCTCGAGACCCACCAGCAGGCC
GACGGCTCGGTCCGGGTGCCGAAGGCGCTCCAGCCCTGGCTGGGCCGCGAGGTCCTGGAGCCGGTCACCACGTGA

Protein sequence :
MIDPRVLRDEPDRVRAAQVKRGLSDEVVDHALSADGERRRAIAAFEAKRAEQKQLGKLIPQAQGEEKQALLAQTKTLAAE
VKQAEAAQAVAEEAWQAALMSIPNLAADEAPAGGEDDYVVLEEIGTPRDFAADGFEPRDHIELGRMLGAIDLDRGAKVSG
SRFYFLTGAGAELELALVNLAMQQARESGFTPVIAPSMVKPRAMDGTGFLGQAADDVYRIEGQDMYLVGTSEVPMAAYHS
DEILDGGALPLRYAAFSPCFRKEAGSHGKDTKGIIRVHWFDKVEMFVYTTTEESYAEHQRLLAWEKEFLEKLELAYRVID
VAAGDLGLSAQRKFDCEAWIPTQGRYRELTSTSNCTEFQTRRLDTRGRFGSEIRPISTLNGTLCAITRTIVAVLETHQQA
DGSVRVPKALQPWLGREVLEPVTT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-54 45