Gene Information

Name : Noca_4946 (Noca_4946)
Accession : YP_919388.1
Strain :
Genome accession: NC_008697
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 281230 - 282660 bp
Length : 1431 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cjk:jk1442 putative mercuric reductase

DNA sequence :
ATGCCGAGGAAGGCCGACCTCGCGGTGATCGGCTCGGGTGGCGCGGCCTATGCCGCGGCGATCCACGCCACCACACTGGG
GAAGTCGGTGGTGATGGTGGAACGCGGCACCATCGGCGGGACATGCGTGAACACCGGCTGCGTGCCGTCCAAGGCGCTGA
TCGCGGCCGCCGAAGCTCGCCATGTCGCTGCCGATGCCGGCCGGTTCCCTGGGATCGCGGCCACCGCGGGCCCGGTGGAC
ATGCCCGCCCTGATCGGGGGCAAGCAGGCGCTGGTGGAGACGCTGCGGGCGGAGAGGTACGTCGACCTCGCTGAGTCCTA
CGGCTGGCCGGTGCTGCCCGGGGACGCGCGCTTCGATGCTACGCCGGACGCGCCGGTGCTGCAGGTGACCGCGGCCGACG
GCACGGTCGAGACGATCGAGGCGGAGCACTACCTGGTCGCCACCGGATCCCGACCTTGGGTCCCGCCGATCGACGGGCTC
GATGCGGTGGACTACCTGACCTCGACAACCGCGATGGAGCTGACCGAGGTGCCGGAGTCACTGCTGGTGCTCGGCGGCGG
CTACGTGGCGTTGGAGCAGGCGCAGCTGTTCGCCCGGCTGGGGTCCCAGGTCACGATGCTGGTGCGGTCCCGGCTCGCAT
CCCGGGAGGAGCCGGAGGCGTCGAGCACGTTGCAGCAGGTCTTTGCCGACGAGGGCATCCGGGTCGTGCGCCGGGCTGCA
GTCACCTCCGTCACGCTCGACGAGACGACCGGTCAGGTGGTGGCCACCGCGGCCGTGTCCGGCGGCGAGCAGGAGTTCCG
GGCCGAGCGGGTGCTGGTGGCGCTGGGTCGCCGCCCGGTCACCGAGGGTCTGAACCTGGACGCGGTGGAGGTGAAGACCG
GCGACCTCGGGGAGATCGTGGTCGACGACCGGCTGGCCTCCTCGAACCCGCGGATCTGGGCGGCCGGGGACGTCACCGGG
CACCGCGAGTTCGTCTACGTCGCCGCCAGCCACGGCGCTGTCGTGGTCGACAACGCCTTCAGCGGAGCAGAGCGGTCGGT
GGACTACGCCCGCCTGCCGCGGGTGACGTTCACCAGCCCTGCGGTCGGGTCGGTCGGGATGACCGACGCCGACGCGGTCG
CCGCCGGCTACCGGTGCGACTGCCGGGTGCTCCCGCTGCAGTACGTGCCCCGCGCGCTGGTGAACCGCGACACCCGCGGC
TTCATCAAGGTCGTCGCCGACGCCGACACCGGCCGGATCCTCGGCCTGACCGCGGTGGCCAAGGACGCCGGCGAGCTCGC
CGCCGCCGGCGTCTACCTCCTCGAGGGTGGAATGACGGTGCAACAGGTCGCCCACGCCTGGGCGCCGTATCTGACCATGG
CCGAAGGCATCAAGATCGCCTGCCAGTCCTATACCACCGACGTCTCCAAGCTGTCCTGCTGCGCCACATGA

Protein sequence :
MPRKADLAVIGSGGAAYAAAIHATTLGKSVVMVERGTIGGTCVNTGCVPSKALIAAAEARHVAADAGRFPGIAATAGPVD
MPALIGGKQALVETLRAERYVDLAESYGWPVLPGDARFDATPDAPVLQVTAADGTVETIEAEHYLVATGSRPWVPPIDGL
DAVDYLTSTTAMELTEVPESLLVLGGGYVALEQAQLFARLGSQVTMLVRSRLASREEPEASSTLQQVFADEGIRVVRRAA
VTSVTLDETTGQVVATAAVSGGEQEFRAERVLVALGRRPVTEGLNLDAVEVKTGDLGEIVVDDRLASSNPRIWAAGDVTG
HREFVYVAASHGAVVVDNAFSGAERSVDYARLPRVTFTSPAVGSVGMTDADAVAAGYRCDCRVLPLQYVPRALVNRDTRG
FIKVVADADTGRILGLTAVAKDAGELAAAGVYLLEGGMTVQQVAHAWAPYLTMAEGIKIACQSYTTDVSKLSCCAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 5e-71 45
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-69 44
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-69 44
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-69 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 7e-69 44
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 8e-69 44
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 1e-84 43
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 9e-85 43
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 4e-68 43
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-68 43
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-68 43
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-67 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Noca_4946 YP_919388.1 mercuric reductase BAC0652 Protein 2e-70 44
Noca_4946 YP_919388.1 mercuric reductase BAC0224 Protein 7e-82 44
Noca_4946 YP_919388.1 mercuric reductase BAC0651 Protein 6e-85 43
Noca_4946 YP_919388.1 mercuric reductase BAC0653 Protein 1e-67 42