Gene Information

Name : Pden_4941 (Pden_4941)
Accession : YP_918697.1
Strain :
Genome accession: NC_008688
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 445920 - 447416 bp
Length : 1497 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: sme:SMA2213 aldehyde

DNA sequence :
GTGACCATGCCCGCCGAAAGCCTGCCGAAACTGTCCATGTATATCGACGGCCAATGGGTCGCTCCGGCGTCGGGGGAATA
TCTCGAGACGGTGGACCCCTATACGGCCAAGCCCTGGGCGCTGGTTCCGCGCGGCAATGCCCAGGACGCCGACCGGGCCA
TCCAGGCCGCGCACCGCGCCTTCAGGGAGGGGCCCTGGGGCAGGATGCATCCCAGCGCGCGCGGCCGCATCATCTCGAAA
TTCGGCGATCTGATCGAGGCGAATGCCGATGCGCTGGCCGAGATCGAGGTGCGCGACAACGGCCGGCTGCTGGCCGAGAT
GCGCCACCAGATCCGCTATATCCCGCGCTGGTATCACTATTACGCCGGCCTGGCCGACAAGATCGAGGGGGCGGTCCATC
CCTGCGACAAGGAGGCGCTGAGCTTTTCGCGCCACGAGCCGCTGGGCGTCTGCGTCGGCATCGTGCCCTGGAACGCGCCG
CTGTTCCTGTTCTCGCTCAAGGCCGCGCCGGCGCTGGCGGCGGGCTGCACCCTGGTGATGAAGCCGGCCGAACATACCTC
GGCCACGGCGCTCAAGCTGATGGAACTGGTCGAGGAGGCGGGGTTTCCACCGGGCGTCATCAACGTCGTCACGGGCTACG
GCCCCGAGGTGGGCGAGCCCCTGGTCACCCATCCGCTGACGCGCCATGTCGGCTTTACCGGCTCGACCAAGACCGGCGCG
CATCTTTACTCGCTGGCGGCCAGGGACATCAAGCGCGTCAGCCTGGAACTGGGCGGCAAGTCCCCCAACATCGTCTTCGA
CGATGCCGACCTGGACAATGCCGTGCGCGGCGTGGTGGGCGGCATCTTCGGCGCCGTGGGCCAGACCTGCATCGCCGGCT
CGCGGCTTCTGGTGCATCGCAAGGTGCATGACCAGTTCCTGGAAAAGCTGGCCGCATTCACCAGGACCGCCCGCATCGGC
GACCCCAGGCACATGGACACCCGGATCGGCCCCATCGCCAACGCAATGCAATATCAAAAGGTGCTGGGCTATATCGACAT
CGCCCGCGATGAGGGTGCCGAACTGGTCCTGGGCGGCAAGCGCCCCGACATCGAGGAATGCGCAAGCGGCTTCTTCATCG
AGCCGACGATCTTTGCCGGCGTGAACAACGACATGCGCATCGCCCGGGAGGAGGTCTTCGGCCCCGTTCTGGCGGCCATC
CCCTTCGACGAGCCCGAAGAGGCCGTCGCCATCGCCAACGACAGCGAATTCGGGTTGGCTGCCGGGGTCTGGACCGCCGA
CATGCGCCGCGCGCTGCTGATGTCCCAGCGGATCGAGGCTGGCAGCGTCTGGGTCAACACCTATCGCGACGTCTCCTACA
CCACGCCCTTCGGCGGCTACAAGAAAAGCGGCATCGGCCGCGAGAACGGCATCGAGGGCATCCGCGAGTTCCTCCAGACC
AAGGCCGTCTGGCTTTCGACCGCCGAGGAAATCGCCAACCCCTTCGTCATCGGATGA

Protein sequence :
MTMPAESLPKLSMYIDGQWVAPASGEYLETVDPYTAKPWALVPRGNAQDADRAIQAAHRAFREGPWGRMHPSARGRIISK
FGDLIEANADALAEIEVRDNGRLLAEMRHQIRYIPRWYHYYAGLADKIEGAVHPCDKEALSFSRHEPLGVCVGIVPWNAP
LFLFSLKAAPALAAGCTLVMKPAEHTSATALKLMELVEEAGFPPGVINVVTGYGPEVGEPLVTHPLTRHVGFTGSTKTGA
HLYSLAARDIKRVSLELGGKSPNIVFDDADLDNAVRGVVGGIFGAVGQTCIAGSRLLVHRKVHDQFLEKLAAFTRTARIG
DPRHMDTRIGPIANAMQYQKVLGYIDIARDEGAELVLGGKRPDIEECASGFFIEPTIFAGVNNDMRIAREEVFGPVLAAI
PFDEPEEAVAIANDSEFGLAAGVWTADMRRALLMSQRIEAGSVWVNTYRDVSYTTPFGGYKKSGIGRENGIEGIREFLQT
KAVWLSTAEEIANPFVIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 6e-73 41
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-72 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-76 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-76 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-76 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Pden_4941 YP_918697.1 betaine-aldehyde dehydrogenase VFG0082 Protein 1e-72 41