Gene Information

Name : Pden_3008 (Pden_3008)
Accession : YP_916787.1
Strain :
Genome accession: NC_008687
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase/ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 180896 - 182563 bp
Length : 1668 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: bur:Bcep18194_B0670 AMP-dependent synthetase and ligase

DNA sequence : 
GTGGCAGATCACGCTCTGGACTGGCAGGCCCGCTGCCCGTTCTGGCCCCGGGACGTTGCTGACCGTTACCGCGAGGCCGG
GATCTGGCGATACGAGACATTCTTCGACCTTCTGGCGCGGCAAGCCGGGCGGCTGGGTCGGCGGATCGCCCTGATCGACG
GTGCGCGGCAGATCGGTTACGACCGGTTGCACTGCGATGCGCTGGCATTGGCGGGCGGGCTTTCGGCGCTGGGGCTGGTC
CGCGGCGACCGGGTGGTGGTGCAATTCCCCAATTGCGGGGAATTCGTCACGCTGTTCTTCGCGCTTTGCCGGCTGGGCGT
CGTGCCGGTGCTGGCCTTGCCCGGGCATCGCGACCTTGAGCTTGGCCAGTTTGCCGATTTCACCGGCGCCCGCGCGATCC
TGACGGCACAGGAGCCCAAGGGGTATGACATGGTCGCGCTGGCCCGGCGGGTGCAAGAGAGGGTTCCCTCGGTTCGGCAC
GTGGTGGCGCTGGGCGACGGCCGAGACGCGACGCCCTTCGACAGCCTGTTCCGTCCCGATCTCCCGTTGCCGGCCGGTCC
CAATGCCGAGGACGTGGCCTGTTTCCAGATCTCGGGCGGGACGACCGGCGTGCCCAAGCTGATCCCGCGCCGGCACATGG
AATATCTCTACAACATCCGGATGGCGGTGGCGGCCAGCGGGCTGGACGGCGATACGCGCTATCTGTGCGTTCTGCCGATG
ATGCACAACTTCCCGATGGCCTGTCCGGGTTTCCTGGGCACGCTGTGGGCCGGGGGCACGGTGGTCGTCGCACCCGAGCC
CGAGGCCGGGATCTGCTTCGACCTGATCGCCCGCCATCGCGTCACGATGACCGCGCTGGTGCCGCCGCTGGCGCTGCTGT
GGCTGGATGCGCAGGCCGGGCTGGGGGCGGACCTGTCGTCGCTGCAACTGCTGCAGGTCGGCGGCGCCAAGTTGAACCCG
TCCAGCGCCCGGCGCATCCGGCCGGAGCTGGGTTGCCAGCTGCAGCAGGTCTTCGGCATGGCCGAGGGGCTGGTCTGCTT
CACCGCGCTGACCGACAGCGAGGAGCGTATCGTGAACACCCAGGGCCGACCCATGTCGCCCTGGGACGAGCTGCGCATCA
TCCGCCCGGATGGGCGCGAGGCCGCCATCGGCGAGCCGGGCGAGCTGCAGGTCCGCGGCCCCTACACGATCCGCGGCTAT
TACGACATGGCCGGGCACAATGCCCAGGCCTTCACCGCCGACGGCTTCTATCGCTCGGGCGACATCGCGCGGCGCGACGC
CGACGGCGCGATTATCGTCGAGGGGCGGGCCAAGGACCAGGTGAACCGGGGCGGCGAAAAGATCGGCGTGGACGAGGTCG
AGGATCTGCTGGTCGCCCATGCCTCGGTGCTGGATGCGGCGGTGGTGGGGCGGCCCGATGCGCTGATGGGCGAAAGGCTT
TGTGCCTTCGTGCTGGCCGCGCCGGGCACCACGCCCCGGCCGGGTGCGCTGCGCCGCCATCTGGCCGAGGCCGGGCTTGC
CGCCTTCAAGATCCCCGACGAGGTGATCGTGCTGGATCGCTTTCCGCAAACCGGCGTCGGCAAGGTCAACAAGCGCCAGT
TGCGCGAGCAACTGCGCGAGGCGCATTTCCCCGATCCCGTCGCTGCCCGGCAGGAGGAGAGTGCATGA

Protein sequence : 
MADHALDWQARCPFWPRDVADRYREAGIWRYETFFDLLARQAGRLGRRIALIDGARQIGYDRLHCDALALAGGLSALGLV
RGDRVVVQFPNCGEFVTLFFALCRLGVVPVLALPGHRDLELGQFADFTGARAILTAQEPKGYDMVALARRVQERVPSVRH
VVALGDGRDATPFDSLFRPDLPLPAGPNAEDVACFQISGGTTGVPKLIPRRHMEYLYNIRMAVAASGLDGDTRYLCVLPM
MHNFPMACPGFLGTLWAGGTVVVAPEPEAGICFDLIARHRVTMTALVPPLALLWLDAQAGLGADLSSLQLLQVGGAKLNP
SSARRIRPELGCQLQQVFGMAEGLVCFTALTDSEERIVNTQGRPMSPWDELRIIRPDGREAAIGEPGELQVRGPYTIRGY
YDMAGHNAQAFTADGFYRSGDIARRDADGAIIVEGRAKDQVNRGGEKIGVDEVEDLLVAHASVLDAAVVGRPDALMGERL
CAFVLAAPGTTPRPGALRRHLAEAGLAAFKIPDEVIVLDRFPQTGVGKVNKRQLREQLREAHFPDPVAARQEESA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-95 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 47
ybtE CAA21394.1 - Virulence HPI Protein 3e-95 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-95 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-95 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-95 47
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-94 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-94 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Pden_3008 YP_916787.1 AMP-dependent synthetase/ligase VFG0168 Protein 5e-120 53
Pden_3008 YP_916787.1 AMP-dependent synthetase/ligase VFG0932 Protein 2e-100 47
Pden_3008 YP_916787.1 AMP-dependent synthetase/ligase VFG1817 Protein 1e-85 45