Gene Information

Name : tpx (Cpha266_0950)
Accession : YP_911422.1
Strain : Chlorobium phaeobacteroides DSM 266
Genome accession: NC_008639
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.5
Position : 1091765 - 1092265 bp
Length : 501 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTACTATTACCTTGAAAGGCAATCCGATCGAGACTTCCGGTTCTCTTCCTCCAGTGGGTTCGGATTCTCCTTTTTT
CTGTCTTGTGAAAACTGATCTTTCGGAGGCAGGCCCTGCTGATTTTGAGGGCAGACGGATGGTGTTCAACATTTTTCCGA
GCCTTGATACGCCGGTTTGCGCGGCTTCTGTAAGACGGTTCAATCAGGAGGCGGCTTCGTTTGATAATACGGTGGTACTT
TGTATTTCAGCCGATCTGCCGTTTGCCCACAGTCGTTTTTGTGAAACGGAGGGGCTGAAAAATGTTGTGTCGCTCTCTTC
TTTTCGCTCTCCGGATTTTGGCAGCAGTTTTGGCGTTTCGATTACGAACGGCCCGTTAAAGGGACTGCTTTGTCGTGCCG
TGGTTATTGTTGATGCTGAACATAAGGTTATCTATAGTGAACTGGTGCCTGAAATTGTTCAGGAACCGGATTATAGTGCG
GCGCTCAAGGCTCTTGCCTGA

Protein sequence : 
MATITLKGNPIETSGSLPPVGSDSPFFCLVKTDLSEAGPADFEGRRMVFNIFPSLDTPVCAASVRRFNQEAASFDNTVVL
CISADLPFAHSRFCETEGLKNVVSLSSFRSPDFGSSFGVSITNGPLKGLLCRAVVIVDAEHKVIYSELVPEIVQEPDYSA
ALKALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-31 47
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 5e-32 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 7e-32 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 4e-32 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_911422.1 thiol peroxidase VFG0087 Protein 2e-32 47