Gene Information

Name : guaA (Cpha266_0300)
Accession : YP_910786.1
Strain : Chlorobium phaeobacteroides DSM 266
Genome accession: NC_008639
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 331874 - 333415 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAATCGGTAACCGTTCTTGACTTTGGATCTCAATATACCCAGCTTATCGCCCGACGTATCCGCGAACTGGGTATCTA
TTCGGAAATACTGCCGTACAATGCCTCTCCTGAAACCATTCGGGAACATGACCCGAAAGCAATTATCCTCTCGGGAGGCC
CGACAAGCGTCTATGGCGATTCTGCCCTTTTACCTGACGGTGGAGTATTCATGCTGGGAGTACCGGTTCTCGGGATCTGC
TATGGTCTGCAGGCCATAGCAAAACATTTCGGAGGGGAGGTTGCCGGCTCTTCTAAACAGGAGTTTGGCAGGGCTAAAAT
GCTGGTCAGTCATAACGAAGAGTCTGAAAGCCCGCTTTTTCGAAACATTCCTGATTCGGATGTCTGGATGAGCCACGGAG
ACAAGGTGGTCAGACTCCCTGAAGGGTTCAGGGTCACCGCAAGCAGCGAAAACTCGGAAATGTGCGCTCTTGAAAGTTAT
GGGTCAAAAGCCGCTCTCAAGGTTTATGGTCTCCAGTTCCATCCTGAAGTACAGCATACCCTTTATGGCAAACAACTGCT
CTCCAACTTTCTCATCGATATTGCTGGCATTAAACCCGATTGGTCGCCGAAAAGCTTTATCGGTCACCAGATTGAGGAAA
TCAGGGCTCGCGCCGGAAAAGACAAGGTGATTTGCGGCATCAGCGGCGGCGTTGACTCAACAGTCGCAGCAGTGCTTGTA
AGCCAGGCTATAGGAAAACAGCTGCACTGCGTTTTTGTTGATAACGGGCTGCTTCGTAAAAATGAAGCGGTCAAAGTGAT
GAATTTTCTCAAACCACTCGGCCTCTCCGTCACCCTTGCCGATGCCTCGGATCTGTTTCTCAAAAGACTTGATAAGGTGG
CCTCTCCGGAAAAAAAGAGAAAGATTATCGGCAGAACCTTCATTCATGTATTCGAACAGCATCTGAACGAGGAGAAATAT
CTTGTTCAGGGCACGCTCTATCCCGATGTCATTGAGAGCGTCAGCGTCAAGGGTCCTTCAGAAACCATCAAGTCGCACCA
TAACGTTGGCGGCCTGCCGAAGCGCATGAAACTGAAACTCATAGAACCGCTCCGGGAGCTTTTCAAGGACGAGGTACGGG
CTGTGGGTCGTGAACTTGGTATTGCTGAAGATATTCTCATGCGCCACCCGTTCCCCGGTCCGGGTCTTGCCGTCAGGGTG
CTGGGCTCGGTAAGTCGCCCAAGGCTTGACATCCTTCGCGAGGCTGATGAAATTTTCATTGAGGAGCTTAAAACCAGCGG
CCTTTACCAGCATGTCTGGCAGGCGTTTTCAGTGCTTCTACCGGTACAGTCTGTCGGCGTCATGGGAGACAAGCGGACGT
ATGAAAATGTTCTGGCACTTCGGGCTGTTGAATCAACGGATGGCATGACCGCCGACTGGGCGCAACTGCCTCACGATTTC
CTCGCACGTGTCTCGAACCGCATCATCAACGAAGTTCGCGGCATCAACCGGGTTGCCTACGATATTTCCTCCAAACCGCC
AGCGACCATCGAGTGGGAGTAA

Protein sequence :
MQSVTVLDFGSQYTQLIARRIRELGIYSEILPYNASPETIREHDPKAIILSGGPTSVYGDSALLPDGGVFMLGVPVLGIC
YGLQAIAKHFGGEVAGSSKQEFGRAKMLVSHNEESESPLFRNIPDSDVWMSHGDKVVRLPEGFRVTASSENSEMCALESY
GSKAALKVYGLQFHPEVQHTLYGKQLLSNFLIDIAGIKPDWSPKSFIGHQIEEIRARAGKDKVICGISGGVDSTVAAVLV
SQAIGKQLHCVFVDNGLLRKNEAVKVMNFLKPLGLSVTLADASDLFLKRLDKVASPEKKRKIIGRTFIHVFEQHLNEEKY
LVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLAVRV
LGSVSRPRLDILREADEIFIEELKTSGLYQHVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAQLPHDF
LARVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-128 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-128 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-121 50