Gene Information

Name : Cpha266_2079 (Cpha266_2079)
Accession : YP_912515.1
Strain : Chlorobium phaeobacteroides DSM 266
Genome accession: NC_008639
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2413654 - 2414397 bp
Length : 744 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAGCAGTTATTCTTATTCCGGCCAGGCTTGATTCCAGTCGGCTTGAAAAAAAAATGCTCGCTGATCTTCAGGGCGA
GCCGCTCATTGTCCGCACCTGGCGTCAGGCGCTGAAATCCCGTCTGGCCGACAGGGTCGTTGTTGCTACCGACAACGATG
AAATCGCCTCGGTGCTGCAGGCATACGGAGCGGAGGTGGTGATGACCTCCCCGCATGCGCGGTGCGGAACAGAGAGGATT
GCAGAAGCGGCAAAAAGCATTGAGGGAGATATCTATGTCAACCTGCAGGGCGACGAGCCCCTCATCAGTCCGGAGAACAT
CGATCTTGCACTGGAGCCGTTTTTCACCGAGACCCCTCCCGATTGCTCGACGCTTGTCTTTCCCTTGCTCCCCGAAGATT
TCCGGCAACTGGAAGATATCAACACCGTCAAGGTTGTGATGGATAATGCGGGATACGCCCTCTATTTTTCGCGCAGCCCG
ATACCCTATCAGCGGCAGATCAGTACGAGCACCGAGTGTTATCGCCATATCGGCCTCTATGCGTTCAGGGCCGATGTCCT
TCATGCTTTTGCATCCCTTGCTCCTTCCATGCTCGAACTTGCCGAATCGCTTGAGCAACTCCGTCTTCTCGAAAACGGCT
ACCGGATCCGGTGCGTGAAAACCACCAGGGACGCGCCGGGAGTCAATACGTATGAAGACCTTGAGCTTGTGCGTCAACTG
CTCAGGAACGCACCGGTTCAGTAA

Protein sequence :
MKAVILIPARLDSSRLEKKMLADLQGEPLIVRTWRQALKSRLADRVVVATDNDEIASVLQAYGAEVVMTSPHARCGTERI
AEAAKSIEGDIYVNLQGDEPLISPENIDLALEPFFTETPPDCSTLVFPLLPEDFRQLEDINTVKVVMDNAGYALYFSRSP
IPYQRQISTSTECYRHIGLYAFRADVLHAFASLAPSMLELAESLEQLRLLENGYRIRCVKTTRDAPGVNTYEDLELVRQL
LRNAPVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-38 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-37 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-38 43