Gene Information

Name : leuS (BAD_0864)
Accession : YP_909727.1
Strain : Bifidobacterium adolescentis ATCC 15703
Genome accession: NC_008618
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1078131 - 1081103 bp
Length : 2973 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTGACACTGAGAAAAGCGCGCAGGCGCAACCGAACGAATCCGCCGAACCGTCGTTCCGCTACAACGCGAAGCTGGC
GCAGGGCATCGAAGAGAAATGGCAGAAGATCTGGGATGACGAAGGCACCTTCTGGGCCGCCAACGTCAACGGCGACCTGA
AGGACGGCAAGGGCCATAACGCAGAAGGCCGCCCGTCCTACTTCGCGATGGACATGTTCCCGTACCCGTCCGGCAAGGGC
CTGCACGTCGGCCACCCGCTGGGCTACCTCGCCACCGACGTGGTCAGCCGCTACCACCGCATGAAGGGTGAGAACGTGCT
GCACGCCATGGGCTACGACGCCTTCGGCCTGCCGGCCGAGCAGTATGCCGTGCAGACCGGCCAGCATCCGCGCATCACCA
CCGAACAGAACATCGCCAACATGCGCCGCCAGCTGCACCGCATGGGCCTGAGCTTCGACAACCGTCGTTCCTTCGCCACC
ATCGACCCCGGCTACGTGCGTTGGACCCAGTGGATCTTCTCCCGCATCTACGACGCCTGGTACGACGAGGACGCCACCAA
CCCGTCCGGCTCCAGGGGCTGCGCCCGCCCGATCAGCACGCTCGTCGAACAGTTCGAATCCGGCAAGCGCGCCATCCCGG
GCTTCGAAGGCAAGGCCTGGGCCGACCTGAGCGAAGCCGAGCAGGCCGACGTGCTCAACGACTTCCGTCTGGCCTACATT
TCCAAGTCCCCGGTCAACTGGTGCCCAGGCCTGGGCACCGTGCTCGCCAACGAGGAGGTCACCGCCGAAGGCAAGTCCGA
ACGCGGCAACTTCCCGGTGTTCCAGCGCGAACTGCGTCAGTGGTCCATGCGCATCACCGCATACGGCCACCGTCTGATCG
AAGACCTCGACACCATCGACTGGCCTGAGAAGGTCAAGCTCATGCAGCGCAACTGGATCGGCGAATCCCACGGCGCTTCC
GTGCATTTCGACGTCGAGACCCCGAACGGCGTCAAGGACATGGAGATCTACACCACCCGTCCCGACACCCTCTTCGGCAC
CACCTTCGCAGTCGTCTCCCCGGAACACCACCTGCTTGAGGACGTGCCTGCCGAATGGCCGGCGGAAACCCCCGAGGATT
GGAAGGGCGGCTACGCCACCCCGGTCGAGGCCGTGAAGGCGTACCGTCTGGCCGCCGAAGCCAAGACCGCCAAGGACCGC
GTGGACGAGGCGGGCGAGAAGACCGGCCTGTTCACCGGCCTGTACGCCATCAACCCGATCACCGGCGCTAAGCTGCCGCT
GTTCACCGCCGACTATGTGCTCATGGACTACGGCACCGGCGCGATCATGGCAGTGCCGGGCGGCGATCAGCGCGATTACG
ATTTCGCCGTCAAGTTCGGCCTGCCGGTCATCTACACCGTCAAGCCGCTGCCGGAATCCGGCGACGACCTCGCCAACTAT
GAGGGCAAGGCGCCGTTCGTCTCCCATGACGGCATCGTCATCAACTCCTCCATCGACGCGACCAAGGCCAAGGGCGATTC
CCTAAGCCTCGACGGCCTGCGCGTGGACGAGGCCATCGACAAGGTCAACGCCTGGCTCGAATCCGCCGGCGTCGGCAAGG
GCACCGTCAGCTACCGTCTACGCGACTGGCTGTTCAGCCGCCAGCGCTACTGGGGCGAGCCGTTCCCGATCGTCTACGGC
GAGGACGGCACTCCGCACCTGCTTCCCGACGAGCAGCTGCCGATCAACCTGCCGGACGTGCCGGACTACAGTCCGAAGAC
CTTCGACCCGGAGGACGCCGAATCCGACCCGGAGGCTCCGCTGAGCCGCAACGAGGACTGGGTCAAGGTCGAGCTCGACC
TGGGCGACGGCAAGAAGACCTACTACCGCGACACCAACACCATGCCGAACTGGGCCGGCTCCTGCTGGTACTACATGCGT
TACCTCGACCCGACCGACACCAAGCACATGGTGGAGAAGGACGAGTTCGACTACTGGATGGGTCCGGACCACAACAAGAC
CGCCGGCAAGTCCGGCGGCGTGGACTTGTACATCGGCGGCGTCGAACACGCCGTGCTGCACCTGCTGTACTCCCGCTTCT
GGCACAAGGTGCTGTTCGACCTCGGCTACGTCGACTCCATGGAACCGTTCCACAAGCTGTTCAACCAGGGCATGATCCAG
GCATACGCCTACACCGACGACCGCGGCCAGTACGTGCCGGCCGCCGAAGTGGTGGAAGGTCCCGCCGACGCCAACGGCGA
GCCGACGTTCACATGGAACGGCCAGCATGCCAACCGCGAGTTCGGCAAGATGGGCAAGAGCCTGAAGAACATCATCACGC
CTGACGACATGTATGAGAACTACGGCGCGGACACCTTCCGCCTGTACGAGATGGGCATGGGCCCGCTGGCCGAATCCCGT
CCATGGAACACCCGCAACGTGGTCGGCTCCATGCGTTTCCTGCAGCGCCTGTGGCGTAACGTCATCGACGAGACCACCGG
CGAGGTGCGCGTCACCGACGGCGAGCTTGACACGAAGACGCTGAAGCTGCTTAACAACACGATCGCCGACGTGACCGTCG
AGATGGAGGCCATGCGTCCGAACACGGCCATCGCCAAGCTCATCGTGCTCAACAACCATCTGACCAGCCTCGACGCCGTG
CCGCGCGCCGCCGTCGAACCGCTGATCCTGATGCTCTCTCCGATCGCCCCGCACATCTGCGAGGAACTGTGGAGCAAGCT
CGGCCACACCGAATCCCTGGCGCACGCCGACTGGCCGAAGGCCGACGAACGTTACGTCGGACAGGATTCCGTCACCGCGG
TCGTGCAGATCAAGGGCAAGGTGCGCGCCAAGCTCGAGGTCTCCCCGGACATCGATCCGAAGGAGCTGGAGAAGATGGCG
CTCGAAGCCGTCGCCGACCGACTGGGCGGCAAGGAGCCACGCAAGGTCATCGTCAAGGCTCCGAAGATCGTCTCCATCGT
TCCCGCGGAATGA

Protein sequence :
MSDTEKSAQAQPNESAEPSFRYNAKLAQGIEEKWQKIWDDEGTFWAANVNGDLKDGKGHNAEGRPSYFAMDMFPYPSGKG
LHVGHPLGYLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLHRMGLSFDNRRSFAT
IDPGYVRWTQWIFSRIYDAWYDEDATNPSGSRGCARPISTLVEQFESGKRAIPGFEGKAWADLSEAEQADVLNDFRLAYI
SKSPVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITAYGHRLIEDLDTIDWPEKVKLMQRNWIGESHGAS
VHFDVETPNGVKDMEIYTTRPDTLFGTTFAVVSPEHHLLEDVPAEWPAETPEDWKGGYATPVEAVKAYRLAAEAKTAKDR
VDEAGEKTGLFTGLYAINPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPESGDDLANY
EGKAPFVSHDGIVINSSIDATKAKGDSLSLDGLRVDEAIDKVNAWLESAGVGKGTVSYRLRDWLFSRQRYWGEPFPIVYG
EDGTPHLLPDEQLPINLPDVPDYSPKTFDPEDAESDPEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMR
YLDPTDTKHMVEKDEFDYWMGPDHNKTAGKSGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSMEPFHKLFNQGMIQ
AYAYTDDRGQYVPAAEVVEGPADANGEPTFTWNGQHANREFGKMGKSLKNIITPDDMYENYGADTFRLYEMGMGPLAESR
PWNTRNVVGSMRFLQRLWRNVIDETTGEVRVTDGELDTKTLKLLNNTIADVTVEMEAMRPNTAIAKLIVLNNHLTSLDAV
PRAAVEPLILMLSPIAPHICEELWSKLGHTESLAHADWPKADERYVGQDSVTAVVQIKGKVRAKLEVSPDIDPKELEKMA
LEAVADRLGGKEPRKVIVKAPKIVSIVPAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-137 45