Gene Information

Name : metB (BAD_0491)
Accession : YP_909354.1
Strain : Bifidobacterium adolescentis ATCC 15703
Genome accession: NC_008618
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 612700 - 613968 bp
Length : 1269 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
CTGTCCGGCAGCCCGATCGCACCTTTGAAACCAATGCCCATCATCCGAACGACCCAAACCATCCGCTACTTCCAAGGAGT
TCCCATCATGACCATCTCGACCAACACCGAAGCCCTCAACGCCACCGCTCTCGCCACCCGCGCCATCCACGCAGGCCAGG
AACCCGACCCGACCACCGGAGCCGTGGTCACCCCCATCTACATGACCTCCACCTTCAAGCAGGACGGCGTCGGCGGCCTG
CGCAACGGCTACGACTACAGCCGTTCCATCAACCCGACCCGCAACAGCTTCGACGAGCAGCTCGCCGCCGTGGAAGGCGC
GAAATACGCGTTAAGCTTCTCCTCCGGACTTGCCGCCATCGACGTGCTGCTGCGCTCCACCCTGAAGCCCGGCGACAACA
TCCTGCTCGGCAACGACGTGTACGGCGGCACCTACCGTCTGCTGTCCAAGGTGTTCGTGCCGTGGGGCATCGGCCTCGAC
GTGGTGGACATCACCGACACGGCCGCCGTCTCAGCCGCGCTCGCCAAGAAGCAGTACGCGTACATCTGGGTGGAAACCCC
GTCCAACCCGCTGCTCAACATCACCGACATCGCCGCCACCGCGGCCGTGGCGCACGCGCACGGCACCAAAGTGGTCGTGG
ACAACACCTTCGCATCCCCGGTATTGCAGCATCCGCTCGCAGACGGCGCCGACGTGGTCGTCTACTCCACCACCAAGTAC
ATCGGCGGCCACTCTGACGTGGTCGGCGGCGCGGTGGTCCTGAACGACAAGGAAACACGCGACGCGGTGGCCTTCCTGCA
GAACGCGGCCGGCGCGGTGCCCTCCCCGTTCGACTCCTGGCTTGACATCCGAGGCCTCAAAACCCTCGACCTGCGCGTCA
AGCAGCACAGCCGCAACGCCATGAAAGTGGCCCAGTGGCTCGAAACCCGCCCCGAAGTGGAACGCGTATGGTATCCGGGG
CTCGAATCCCACCCGGGCCACGACATCGCGGCACGCCAGATGCACGGCGGTTTCGGCGGCATGATCTCCATCCAGATCGC
CGCCGGTTTCGAAGCGGCCAAGAAGTTCGCCGGAGCCACCGAAGTGTTCACCCTGGCCGAATCCCTGGGCGGCGTGGAAT
CCCTGATCGAGCATCCGGGCGCCATGACCCACGCCTCCGTGGCCGGCACCACGCTCGAAGTGCCCGCCAACCTGATCCGC
CTGTCCGTCGGCCTTGAGGACGCGGACGATCTGATCGCTGACCTGGAGCAGGCGTTCCGCCAGATCTGA

Protein sequence :
MSGSPIAPLKPMPIIRTTQTIRYFQGVPIMTISTNTEALNATALATRAIHAGQEPDPTTGAVVTPIYMTSTFKQDGVGGL
RNGYDYSRSINPTRNSFDEQLAAVEGAKYALSFSSGLAAIDVLLRSTLKPGDNILLGNDVYGGTYRLLSKVFVPWGIGLD
VVDITDTAAVSAALAKKQYAYIWVETPSNPLLNITDIAATAAVAHAHGTKVVVDNTFASPVLQHPLADGADVVVYSTTKY
IGGHSDVVGGAVVLNDKETRDAVAFLQNAAGAVPSPFDSWLDIRGLKTLDLRVKQHSRNAMKVAQWLETRPEVERVWYPG
LESHPGHDIAARQMHGGFGGMISIQIAAGFEAAKKFAGATEVFTLAESLGGVESLIEHPGAMTHASVAGTTLEVPANLIR
LSVGLEDADDLIADLEQAFRQI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-61 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-63 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-46 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_909354.1 cystathionine gamma-synthase BAC0207 Protein 2e-46 41