Gene Information

Name : thyA (BAD_0388)
Accession : YP_909251.1
Strain : Bifidobacterium adolescentis ATCC 15703
Genome accession: NC_008618
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 488153 - 488953 bp
Length : 801 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCCTTACGAGGATCTGGTACGCAAAATCCTTACGGAAGGCACACTGAAATCCGACCGCACGGGCACGGGCACTATTTC
CCTGTTCGGCCAGCAGATGCGTTTCAATCTCAAAGACAGCTTCCCACTGCTCACCACGAAGACGGTGTTCTTCAAAGGCC
TGGCCTACGAGCTGCTGTGGTTCCTCAAAGGCTCCACGAACGTACGTTGGCTGCAGGAGCACAACGTGCACATTTGGGAC
GAATGGGCCGACGAGAACGGCGATTTGGGGCCGGTCTACGGCGCGCAGTGGCGTAGCTGGCCGGCGCCGACGCCGGACGA
TCCGAACCGCACGATCGACCAGATCTCCAATGTGCTCGACCTGATCCGTAACCACCCCGATTCGCGCCGCATGGTGGTTT
CCGCATGGAATCCGGCGGAAGTGGAGAATATGGCATTGCCGCCATGCCACGCCCTATTCCAGTTCTACGTGGCCGACGGC
CGCCTGAGCTGCCAGCTGTACCAGCGTTCCTGCGACATATTCCTCGGCGTGCCGTTCAACATCGCCTCCTATTCGCTGCT
CACCCTCATGATGGCCCAGCAGACGGGACTCGAGCCCGGCGAATTCGTTTGGACCGGCGGCGACTGCCACGTCTACGACA
ACCACATCGACCAGGTGTTGGAACAGCTGAGCCGTACGCCGTACCCGTATCCGCAGATCCGCATCAGGAAGGCCGATTCG
CTGTTCGACTACGATTACAGCGATTTCGAAATCGTGAATTACCAGCATCATCCGACCATCAAGGCACCGGTGGCGGTCTG
A

Protein sequence :
MPYEDLVRKILTEGTLKSDRTGTGTISLFGQQMRFNLKDSFPLLTTKTVFFKGLAYELLWFLKGSTNVRWLQEHNVHIWD
EWADENGDLGPVYGAQWRSWPAPTPDDPNRTIDQISNVLDLIRNHPDSRRMVVSAWNPAEVENMALPPCHALFQFYVADG
RLSCQLYQRSCDIFLGVPFNIASYSLLTLMMAQQTGLEPGEFVWTGGDCHVYDNHIDQVLEQLSRTPYPYPQIRIRKADS
LFDYDYSDFEIVNYQHHPTIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-89 68
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-59 45