Gene Information

Name : clpB (BAD_1464)
Accession : YP_910327.1
Strain : Bifidobacterium adolescentis ATCC 15703
Genome accession: NC_008618
Putative virulence/resistance : Virulence
Product : chaperone clpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1845569 - 1848286 bp
Length : 2718 bp
Strand : -
Note : Orthologue of Rv0384c_BL1250; Probable clpB(alternate gene name: htpM)_ endopeptidase ATP-bindingprotein_ chain B (EC 3.-.-.-)

DNA sequence :
ATGGAACAGAAGTTCACGCAGATGGCGCAGGAAGCGCTTTCGGACGCCGTTCAGAACGCGGCGGCGCTGGGCAATCCGCA
GGTAGACACCCTGCACCTGCTGGACGCGATGCTGCGTCAGGAAAACAGCATGGCCCGCGCGCTCATCGAAGCGGCAGGCG
GCAACGCGCAAAACGTGAGCGCCGAAGTGCATCAGGCGATGCAATCGCTGCCGAGCGCCAGCGGATCGACCACAACGCAG
CCGGACGTCAGCAGGCAGCTGTCGGCGGTGCTATCGCAAGCCGAAAAAGAAATGCAACGGAGGGGAGACGAGTACGTCAC
CGTCGACCTCATGCTGGTCGCAATCGCGGCCGCGAAACCTAATCAAAGCGCGGACATCTTGGAAAAGAACGGTCTTACCG
CGGATAAGCTGCGTAACGCCCTGACCGCCGCGCGCGGCAGCGACCGCAAGGTGACCAGCGCCGACGCGGAAGGCTCGTAT
AAAGCTTTGGAGAAGTACTCCACCGATTTGACGGCCGCCGCGAAGGAAGGCAAGCTCGACCCGGTGATCGGCCGCGACCA
GGAAATCCGCCGCGTCATCCAGATCCTGTCCCGCCGTACCAAGAACAATCCTGTGCTGATCGGCGAGCCTGGCGTCGGCA
AAACCGCCGTCGTCGAAGGCCTGGCGCAGCGCATCGTCGCCGGCGACGTGCCGACCACCCTGCAGAACAAGAAGCTTATC
TCGCTTGACCTGGGCTCCATGGTGGCTGGTTCCAAGTACCGTGGCGAATTCGAGGAACGTCTGAAGAGCGTGCTTGAGGA
GATCAAGAAGGCCGACGGGCAGATCATCACCTTCATCGACGAGATCCACACCATCGTCGGCGCGGGCGCGGCCGAAGGCT
CCATGGACGCGGGCAATATGCTCAAGCCCATGCTGGCCCGTGGCGAACTGCGCCTGATCGGCGCCACCACACTGGACGAA
TACCGTGAGAACATCGAAAAGGATCCGGCGCTCGAACGTCGTTTCCAGCAGGTGTTCGTCGGCGAGCCGAGCGTGGAGGA
CACCGTCGCCATCCTGCGCGGCATCGCGCCGAAGTATGAGGCCCACCACAAGGTGACCATCGGCGACGACGCGCTGGTCG
CGGCGGCAACCCTGTCGAACCGCTACATTTCCGGACGCCAGCTGCCGGACAAGGCCATCGATCTGGTGGACGAGGCCGCA
GCGCACCTGCGCATGGAACTCGACTCCTCGCCTGAGGAAATCGACGAACTGCGCCGCCAGGTGGACCGTCTCAAGATGGA
GAAGTCGTACCTGCTGGGCAATCCGAAGAACGACAAGGCCACGGAAAAGGCCGAAGCGGAACTGGACGACAGCGCCAAGG
ACCGTCTCGCCGATTTGAACCAGGAAATCGCCGACAAAAGCGAAAAGCTCAACGGGCTGAAAGCGCGTTGGGACGCCGAA
AAGAACGGCCACAACCGTATCGGCGACCTGCGCAAGAAGCTCGACGAGCTGCGTACGCAAGCCGAAAAGTACGAGCGCGA
AGGCGACCTGGCGAAATCGTCAGCCATCAACTACGGCGAAATCCCGGCCATCCAGAAGGAAATCGCCCAAGCCGAGAAGA
ACGAGGCGGAATCGGGCGGAGCCGACAATGCCAACGCCGACGTGCCGATGGTCCCCGACCGCGTCGACGCCGACTCCATC
GCCGAAATCGTCTCCGACTGGACCGGCATCCCCGTGGGCCGTCTTATGCAGGGCGAAAACGAGAAGCTCCTGCACATGGA
GGAGTACCTCGGCAAGCGTGTGATCGGCCAGAAGGAAGCCATCCAAGCGGTTTCCGACGCCGTGCGTCGCTCGCGTGCCG
GCATCTCCGACCCGAACCGTCCGACCGGATCGTTCCTGTTCCTCGGCCCCACCGGCGTGGGCAAGACCGAACTGGCCAAG
GCGCTCGCCGACTTCCTATTCGATGACGAGAAGGCCATGGTGCGCATCGACATGAGCGAATACATGGAGAAGGCCTCCGT
GTCCCGCCTGATCGGCGCCGCGCCGGGCTACATCGGCTACGAAGAGGGTGGCCAGCTTACCGAAGCCGTGCGTCGCCGTC
CGTATTCGGTGGTGCTGTTCGACGAGGTGGAGAAGGCCAATCCGGAAGTCTTCGACGTGCTGCTGCAGGTGCTTGACGAC
GGTCGCCTGACCGACGGCCAGGGCAGGACCGTGGACTTCAAGAACACGATTCTGATCATGACCTCCAACCTGGGCTCGCA
GTTCCTCGTCAATCCCGACATGGACGCGGACGCCAAGAAGAAGGCCGTGATGGACGCCGTGCACATGCAGTTCAAGCCGG
AATTCATCAACCGTCTGGACGAACTGGTCATGTTCCACCCGCTGACCCGCGAGGAGCTCGGCGGCATCGTGGACATTCAG
GTCGCGCAGGTGTCCGCACGTCTGACCGACCGCCGCATCACGCTCGACGTGACCGATTCGGCGCGCGAATGGCTTGCCAA
CACCGGTTACGATCCGGCGTACGGCGCACGTCCGCTGCGTCGCCTGGTGCAGACCGAAGTCGGCGACCAGCTTGCCCGCA
TGCTGCTGGCCGGCGAAGTGCACGACGGCGACACCGTGCTGGTGGACCAGACCGGCGGCGACCACCTGGAGCTGTCCGCG
TGGGCCGCGGACCAGCTGGAGGATATGGGCGAGGGGAAGACGGACGATTCCGCCGACGTCCCGAACCCGGCTGAGTGA

Protein sequence :
MEQKFTQMAQEALSDAVQNAAALGNPQVDTLHLLDAMLRQENSMARALIEAAGGNAQNVSAEVHQAMQSLPSASGSTTTQ
PDVSRQLSAVLSQAEKEMQRRGDEYVTVDLMLVAIAAAKPNQSADILEKNGLTADKLRNALTAARGSDRKVTSADAEGSY
KALEKYSTDLTAAAKEGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNKKLI
SLDLGSMVAGSKYRGEFEERLKSVLEEIKKADGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATTLDE
YRENIEKDPALERRFQQVFVGEPSVEDTVAILRGIAPKYEAHHKVTIGDDALVAAATLSNRYISGRQLPDKAIDLVDEAA
AHLRMELDSSPEEIDELRRQVDRLKMEKSYLLGNPKNDKATEKAEAELDDSAKDRLADLNQEIADKSEKLNGLKARWDAE
KNGHNRIGDLRKKLDELRTQAEKYEREGDLAKSSAINYGEIPAIQKEIAQAEKNEAESGGADNANADVPMVPDRVDADSI
AEIVSDWTGIPVGRLMQGENEKLLHMEEYLGKRVIGQKEAIQAVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAK
ALADFLFDDEKAMVRIDMSEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEVEKANPEVFDVLLQVLDD
GRLTDGQGRTVDFKNTILIMTSNLGSQFLVNPDMDADAKKKAVMDAVHMQFKPEFINRLDELVMFHPLTREELGGIVDIQ
VAQVSARLTDRRITLDVTDSAREWLANTGYDPAYGARPLRRLVQTEVGDQLARMLLAGEVHDGDTVLVDQTGGDHLELSA
WAADQLEDMGEGKTDDSADVPNPAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-107 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-109 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-109 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_910327.1 chaperone clpB VFG2084 Protein 4e-113 43