Gene Information

Name : katE (MUL_4291)
Accession : YP_907779.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Unknown
Product : catalase KatE
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0753
EC number : -
Position : 4763200 - 4764648 bp
Length : 1449 bp
Strand : -
Note : Also detected in the membrane fraction by proteomics (LC-MS/MS); cytoplasmic protein; protects against oxidative stress. converts hydrogen peroxide to water and molecular oxygen.

DNA sequence :
ATGGCGGAACGCTACACCACCACCGACGCCGGCAATCCCGCGCCCAGTGACGACCAATCGCTGACCATCGGCCCCGACGG
ACCGATCCTGCTGCAGGATCACTACCTGATCGAACAGATGGCGATGTTCAACCGGGAACGCATCCCGGAACGCCAGCCAC
ACGCCAAAGGTGGCGGCGCGCACGGCCACTTCGAGGTGACCCACGACGTCAGCAAGTACACCCGGGCGGCGGTGTTCGCG
CCAGGTGCCAAGACGGACACGCTGATCCGCTTCTCCACCGTTGCCGGCGAGCGCGGCAGCCCGGACACCTGGCGGGACCC
GCGTGGTTTCGCGTTGAAGTTCTATACCTCAGAGGGAAACTTCGACATGGTCGGCAACAACACGCCGGTCTTCTTCATGC
GCGACCCGTTGAAATTCCAGCACTTCATCCGGTCCCAGAAGCGCATGCAGGCAACGAATCTGCGTGACCACAACATGCAA
TGGGACTTCTGGAGCCTGTCGCCGGAGTCCGCGCACCAGGTGACCTGGCTGATGGGTGATCGGGGGATTCCCAAGAGCTG
GCGCCAGATGAACGGCTACAGCAGCCACACCTACAGCTGGATCAATGCCGCCGACGAGATCTTCTGGGTGAAGTACCACT
TCATCACCGATCAGGGCATCGACTTCCTCACCCAAGAGGACGCCGACCGGTTGGCCGGTACGGACGGCGACTACCACCAG
CGCGACCTCTACGAAGCGATCGAGCGCGGTGACTTTCCCAGTTGGACACTCAAAATGCAGATCATGGGGTTCGAAGAGGC
CAAGAGCTATCGGTTCAATCCCTTCGATCTGACCAAGGTCTGGCCACACAGCGACTATCCGTTGATCGATGTCGGCAAGT
TGACCTTGGACCGCAACGTCACCGACTACCACACCGAGATCGAGCAAGCGGCGTTCGAGCCCAACAACATCGTGCCCGGT
ACCGGGCTGAGCCCGGACAAGATGCTCTTGGCCCGAGGGTTCTCCTACTCCGACGCGCACCGGGCCCGGTTGGGCACCAA
TTACCGCCAGATCCCGGTGAATTCGCCGATAGTGCAGGTCAATAGCTACTCCAAGGATGGCGCGATGCGGGTGCGCAACG
CGTCGGATCCGGTATACGCGCCCAACTCCTATGGTGGCCCCCAGGCCGATCCGGCCCGCGCCGCGGAGGTGCGCTGGCAC
GCCGATGGGCAGATGATGCGCGCCGCGTACACGCCGCACCCCGAAGACGACGACTGGGGCCAGGCCGGCACCATGGTCCG
CGAAGTTCTCGACGATTCAGCACGGGATCGGTTGGCCAGCAACATCATTGGGCATATTTGCAAAGGTGTGAAGGAGCCGG
TGCTCTCGCGCGTCTTCGAGTATTGGCGCAATGTCGATCCCGATCTGGGCAAGGCGGTTGAGGAAGGGGTGCGGGCCAAT
TCCAGTTGA

Protein sequence :
MAERYTTTDAGNPAPSDDQSLTIGPDGPILLQDHYLIEQMAMFNRERIPERQPHAKGGGAHGHFEVTHDVSKYTRAAVFA
PGAKTDTLIRFSTVAGERGSPDTWRDPRGFALKFYTSEGNFDMVGNNTPVFFMRDPLKFQHFIRSQKRMQATNLRDHNMQ
WDFWSLSPESAHQVTWLMGDRGIPKSWRQMNGYSSHTYSWINAADEIFWVKYHFITDQGIDFLTQEDADRLAGTDGDYHQ
RDLYEAIERGDFPSWTLKMQIMGFEEAKSYRFNPFDLTKVWPHSDYPLIDVGKLTLDRNVTDYHTEIEQAAFEPNNIVPG
TGLSPDKMLLARGFSYSDAHRARLGTNYRQIPVNSPIVQVNSYSKDGAMRVRNASDPVYAPNSYGGPQADPARAAEVRWH
ADGQMMRAAYTPHPEDDDWGQAGTMVREVLDDSARDRLASNIIGHICKGVKEPVLSRVFEYWRNVDPDLGKAVEEGVRAN
SS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
katA YP_005126717.1 catalase Not tested Not named Protein 1e-122 52
katA YP_003782575.1 catalase Not tested PiCp 3 Protein 6e-121 52
katA YP_005684630.1 catalase Not tested PiCp 3 Protein 6e-121 52
katA YP_005680448.1 catalase Not tested PiCp 3 Protein 6e-121 52
katA YP_005682539.1 catalase Not tested PiCp 3 Protein 6e-121 52
katA ABD94664.1 catalase isozyme A Not tested ExoU island A Protein 1e-101 48