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Name : clpC1 (MUL_4178) Accession : YP_907684.1 Strain : Mycobacterium ulcerans Agy99 Genome accession: NC_008611 Putative virulence/resistance : Virulence Product : ATP-dependent protease ATP-binding subunit ClpC1 Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 4648646 - 4651195 bp Length : 2550 bp Strand : - Note : Also detected in the extracellular matrix by proteomics.; cytoplasmic protein; hydrolyses proteins in presence of ATP. may interact with a ClpP-like protease involved in degradation of denatured proteins. DNA sequence : ATGTTCGAACGCTTTACCGACCGTGCCCGCCGGGTCGTTGTCCTGGCGCAAGAAGAGGCCCGGATGCTGAACCACAACTA CATCGGCACCGAGCACATTCTGCTGGGGCTAATCCATGAAGGCGAAGGCGTTGCGGCCAAGTCGCTGGAGTCGCTCGGGA TCTCGCTGGAAGGTGTGCGCAGCCAGGTCGAAGAGATCATCGGCCAGGGCCAGCAGGCACCGTCCGGGCACATCCCGTTC ACTCCGCGCGCCAAGAAGGTGCTCGAACTCAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGTACCGAGCA CATCCTGCTCGGCCTGATTCGCGAGGGCGAGGGTGTGGCCGCCCAGGTGCTGGTCAAGCTGGGCGCCGAACTGACCCGGG TGCGCCAGCAGGTGATCCAGCTGCTGAGCGGCTACCAGGGCAAGGAGGCCGCCGAGGCAGGCACCGGCGGCCGGGGAGGG GAGTCCGGCTCTCCCTCCACGTCGCTGGTTCTCGACCAGTTCGGCCGCAACCTGACCGCGGCTGCCATGGAAGGCAAGCT GGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTCTCCCGGCGCACCAAGAACAACCCGGTGC TCATCGGCGAGCCCGGCGTGGGCAAGACCGCTGTGGTCGAGGGCCTGGCGCAGGCCATCGTGCACGGCGAGGTGCCCGAG ACGCTGAAGGACAAGCAGCTCTACACGCTGGACCTCGGCTCGCTGGTCGCGGGTTCGCGCTACCGTGGTGACTTCGAGGA ACGCCTGAAGAAGGTGCTCAAGGAGATCAATACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCG GGGCGGGTGCCGCCGAGGGCGCGATCGATGCCGCAAGCATCCTCAAGCCCAAGCTGGCTCGCGGCGAGCTGCAGACGATC GGTGCCACCACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCGCTGGAGCGCCGTTTCCAGCCGGTGCAGGT GGGGGAGCCGACGGTCGAGCACACCATCGAGATCCTCAAGGGCCTGCGGGACCGCTACGAGGCGCACCACCGCGTGTCGA TCACCGATTCCGCGATGGTGGCCGCCGCGACGCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC GACCTGATCGACGAGGCGGGCGCCCGGATGCGGATCCGTCGCATGACCGCGCCGCCAGACCTGCGCGAGTTCGACGAGAA GATCGCCGACGCGCGCCGGGAGAAGGAATCGGCGATCGACGCCCAGGACTTCGAGAAGGCGGCGAGCCTGCGCGACCGGG AGAAGCAACTGGTGGCGCAGCGTGCCGAGCGTGAAAAGCAATGGCGTTCGGGCGATCTCGACGTGGTCGCCGAAGTCGAT GACGAACAGATCGCCGAAGTGCTGGGCAACTGGACTGGCATCCCGGTGTTCAAGCTCACCGAGGCGGAAACCACCCGCCT GCTGCGGATGGAAGATGAGCTGCACAAGCGGATCATCGGCCAGGAAGACGCGGTCAAGGCGGTCTCCAAGGCGATCCGCC GCACCCGCGCCGGGCTGAAGGACCCGAAGCGCCCGTCGGGATCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC GAGCTGTCCAAGGCGCTGGCCAACTTCTTGTTCGGTGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA CCGGTTCACCGCGTCCCGGCTCTTCGGTGCTCCGCCCGGATATGTCGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGG TGCGGCGCAAGCCGTTCAGCGTGGCGCTCTTCGATGAGATCGAGAAGGCACACCAGGAGATCTCCAACAGTCTGTTGCAG GTCCTCGAGGACGGCCGGCTCACCGACGGCCAGGGCCGCACGGTCGACTTCAAGAACACCGTGCTGATCTTCACGTCGAA TCTGGGGACATCCGATATTTCCAAGCCCGTCGGCCTCGGGTTCAGCCAGACTGGCGGCGAGAACGACTACGAGCGGATGA AGCAGAAGGTCAACGACGAGCTCAAGAAGCACTTCCGGCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC CAGCTGACTCGCGACGAGATCATCCGGATGGTCGACCTGATGATCGGCCGCGTCGCCAACCAGCTCAAGAGCAGCAAGGA CATGGCGCTCGAGCTGACCGACAAGGCAAAGTCGCTGCTGGCCAAGCGCGGTTTCGACCCGGTCTTGGGTGCTCGTCCGC TGCGGCGAACCATTCAGCGTGAGATCGAGGACCAGCTCTCGGAGAAGATCCTCTTCGAGGAGGTCGGTCCGGGACAGGTC GTCACCGTCGACGTCGACAACTGGGACGGCGAGGGCGCCGGTGAGGACGCGAAATTTACGTTCACCGGTACCCGCAAGCC GCCGAGTGAGCCGGACCTGGCAAAGGCCGGAGCACACAGCGCCGGGGGACCTGGGCCCACCGAGCAGTAA Protein sequence : MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVALFDEIEKAHQEISNSLLQ VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFH QLTRDEIIRMVDLMIGRVANQLKSSKDMALELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV VTVDVDNWDGEGAGEDAKFTFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 0.0 | 81 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpC1 | YP_907684.1 | ATP-dependent protease ATP-binding subunit ClpC1 | VFG0079 | Protein | 0.0 | 60 |
| clpC1 | YP_907684.1 | ATP-dependent protease ATP-binding subunit ClpC1 | VFG0080 | Protein | 8e-148 | 51 |
