Gene Information

Name : pncB (MUL_3932)
Accession : YP_907472.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Unknown
Product : nicotinate phosphoribosyltransferase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1488
EC number : 2.4.2.11
Position : 4387128 - 4388444 bp
Length : 1317 bp
Strand : +
Note : catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate

DNA sequence :
GTGAACCACTCGGTCCTGGCTGGGCTGCTGACCGACAAGTACGAGATGACCATGCTGGCGGCCGCGCTGCGCGACGGCAC
CGCCGAGCGCCGGACGTCCTGGAAGGTCTTCGCCCGTCGGCTGCCCGCCGGCCGCAGATACGGGGTGGTGGCCGGGACCG
GCCGCCTCCTGGAACTCTTGCCCCGGTTCGGCTTCGACGACCAAGCATGCGAGTTGCTGGCCCAATTCCTGGGTCCAGAC
ACCGTGGCTTACCTGCGCGACTTCCGGTTCAGCGGCGACATCGACGGCTATGCCGAAGGCGAGCTTTACTTCCCCGGGTC
CCCCGTGCTCTCGGTACACGGCAGCTTCGCCGAATGCGTGCTGCTGGAGACTCTGGTGCTGTCGGTCTTGAATCACGACT
CAGCGATCGTCTCGGCCGCGGCCCGGATGGTCAGTGCCGCCGGCGATCGCCCCTTGATCGAAATGGGTTCGCCACGCACC
CACGAGTGCGCCGCGGTCGCTACCGCCCGAGCCGCATACATTGCCGGGTGCACCGGCTCCTCCAATCTGGAAGCCCGGCA
ACTCTACGGCGTCCCCGCCGAGGGCACCGCCGCGCACGCGTTCACCATGGTGCATATCAACCAGGACCGCACACCGGCCT
TGGCCGAGCTGGCCGCGTTCCGGGCCCAGATCGACGCGCTCGGGCCGGACACCACGCTGCTCGTCGATACCTATGACGTG
ACGACCGGGGTGGCCAACGCCGTGGCCGCCGCGGGTACGGCTCTGGGCGCGGTCCGCATCGACTCCGGCGAGCTGGGTGT
ACTCGCCTGGCAGGCGCGCCAGCAACTCGACGCCTTGGGCGCCACCGAAACCCAAATCATGGTCTCGGGCGATCTGGACG
AGTTCTCCATCGCCGCGCTGCGCGCGGAGCCGGTCGATCGCTACGGCGTCGGCACCTCGCTGGTCACCGGCTCGGGCGCA
CCAACGGCGAGCATGGTTTACAAACTTGTTGAGGTCGAAGGCATTCCGGTGCAGAAGCGCAGCAGCCAGAAGGAATCCCG
CGGTGGTCGCAAGGAGGCGCTGCGGCTGGCGCGACCGACGGGAACCGTCACCGAGGAGATCGTGCACCCGGCCGGTCGAC
CGCCGGCCACCACGGGGCTACACCGGGTGTTGACGACACCGCTGGCTCGCAGCGGAAAGCCGATGGTCACCACCGATCCA
GATACTCTCGCCGCAGCCCGAAAGCTGGTGGCGTCTGGGCTACGCAGCTTGCCTTGGGAGGGACTGAAATTGGCACCCGG
CGAACCCGCCATCCCGACCCAGACCATCTCGGCCTGA

Protein sequence :
MNHSVLAGLLTDKYEMTMLAAALRDGTAERRTSWKVFARRLPAGRRYGVVAGTGRLLELLPRFGFDDQACELLAQFLGPD
TVAYLRDFRFSGDIDGYAEGELYFPGSPVLSVHGSFAECVLLETLVLSVLNHDSAIVSAAARMVSAAGDRPLIEMGSPRT
HECAAVATARAAYIAGCTGSSNLEARQLYGVPAEGTAAHAFTMVHINQDRTPALAELAAFRAQIDALGPDTTLLVDTYDV
TTGVANAVAAAGTALGAVRIDSGELGVLAWQARQQLDALGATETQIMVSGDLDEFSIAALRAEPVDRYGVGTSLVTGSGA
PTASMVYKLVEVEGIPVQKRSSQKESRGGRKEALRLARPTGTVTEEIVHPAGRPPATTGLHRVLTTPLARSGKPMVTTDP
DTLAAARKLVASGLRSLPWEGLKLAPGEPAIPTQTISA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1473 YP_001800867.1 nicotinate phosphoribosyltransferase Not tested Not named Protein 9e-95 60