Gene Information

Name : mmr (MUL_3425)
Accession : YP_907069.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Resistance
Product : multidrug-transport integral membrane protein Mmr
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2076
EC number : -
Position : 3796102 - 3796425 bp
Length : 324 bp
Strand : +
Note : membrane protein; involved in transport of multidrugs (tetraphenylphosphonium, erythromycin, ethidium bromide, acriflavine, safranin O, pyronin Y, etc) across the membrane (export): multidrugs resistance by an export mechanism (conferes resistance to toxi

DNA sequence :
GTGGCTTACCTACTGTTGTTGGGCGCGATCGCCATGGAGGTGATGGCGACCAGCTTCCTGAAGAGCACCGAGGGCTTCAC
CCGACTGTGGCCCACGGTGATCTGCTTGACGATCTATGGCTTCTCCTTCGCGATGCTGGCGATGTCGACCGCGCGCGGCA
TGCAAACCGACGTCGCATACGCGCTGTGGTCGGCCATCGGCACCGGCGCCATCGTCCTCATCGTCGTGCTCTTCCTCGGC
TCACACTTGTCGCTGACCAAGGTCCTCGGAGTGGGGCTGATCATCGGCGGCGTGCTCACGCTGAACCTGACCGGCGCCCA
TTGA

Protein sequence :
MAYLLLLGAIAMEVMATSFLKSTEGFTRLWPTVICLTIYGFSFAMLAMSTARGMQTDVAYALWSAIGTGAIVLIVVLFLG
SHLSLTKVLGVGLIIGGVLTLNLTGAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
qacEdelta1 AGK36647.1 QacEdelta1 Not tested AbaR26 Protein 3e-06 41
qacEdelta1 AGK06933.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacE-deltal ACF06159.1 quartenary ammonium compound resistance protein Not tested Tn5036-like Protein 3e-06 41
qacEdelta1 AAK02047.1 quaternary ammonium compound and disinfectant protein Not tested SGI1 Protein 3e-06 41
qacEdelta1 AGK06970.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacE-delta1 ACY75523.1 QacE-delta1 Not tested Tn6060 Protein 3e-06 41
qacEdelta1 AAK02056.1 quaternary ammonium compound and disinfectant protein Not tested SGI1 Protein 3e-06 41
qacEdelta1 AGK06979.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacE-delta1 ACY75532.1 QacE-delta1 Not tested Tn6060 Protein 3e-06 41
qacEdelta1 ABB48428.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacEdelta1 AGK07016.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacE-delta1 AET25389.1 QacE-delta1 Not tested PAGI-2(C) Protein 3e-06 41
qacEdelta1 ABZ01839.1 QacEdelta1 Not tested SGI2 Protein 3e-06 41
ACICU_00227 YP_001844886.1 membrane transporter Not tested AbaR20 Protein 4e-06 41
qacEdelta1 AGK07074.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacE-delta1 AFG30112.1 QacE-delta1 Not tested PAGI-2 Protein 3e-06 41
qacEdelta1 CAJ77030.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 3e-06 41
qacEdelta1 YP_005797134.1 quaternary ammonium compound-resistance protein Not tested AbaR4e Protein 4e-06 41
qacEdelta1 AGK07100.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacEdelta1 AGF34989.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacEdelta1 CAJ77049.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 3e-06 41
qacEdelta1 YP_005797150.1 quaternary ammonium compound-resistance protein Not tested AbaR4e Protein 4e-06 41
qacEdelta1 AGK07109.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacEdelta1 AGF35028.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacEdelta1 CAJ77052.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 3e-06 41
ebr YP_006098377.1 putative ethidium bromide resistance protein Not tested Tn2411 Protein 4e-06 41
qacEdelta1 AFV53123.1 QacEdelta1 multidrug exporter Not tested AbGRI2-1 Protein 3e-06 41
qacEdelta1 AGF35063.1 QacEdelta1 Not tested SGI1 Protein 3e-06 41
qacEdelta1 CAJ77088.1 Quaternary ammonium compound-resistance protein Not tested AbaR1 Protein 3e-06 41
qacEdelta1 ACN81026.1 QacEdelta1 Not tested AbaR5 Protein 4e-06 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mmr YP_907069.1 multidrug-transport integral membrane protein Mmr BAC0249 Protein 6e-23 74
mmr YP_907069.1 multidrug-transport integral membrane protein Mmr AE000516.2.gene3301. Protein 6e-23 74
mmr YP_907069.1 multidrug-transport integral membrane protein Mmr NC_002695.1.913273.p Protein 7e-08 44
mmr YP_907069.1 multidrug-transport integral membrane protein Mmr BAC0150 Protein 6e-08 44
mmr YP_907069.1 multidrug-transport integral membrane protein Mmr BAC0322 Protein 1e-06 41
mmr YP_907069.1 multidrug-transport integral membrane protein Mmr BAC0323 Protein 1e-06 41