Gene Information

Name : guaB1 (MUL_3036)
Accession : YP_906759.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.205
Position : 3360151 - 3361587 bp
Length : 1437 bp
Strand : +
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
ATGAGGTTCTTGGACGGGCATCGGCCCGGGTACGACCTGACGTACAACGACGTATTCATCATGCCGAATCGCTCCCTGGT
GGCGTCCCGGTTCGACGTGGATCTGTCGACCGCCGACGGTTCGGGTACCACCATTCCCGTGGTGGTGGCCAACATGACCG
CGGTGGCCGGGCGGCGGATGGCCGAGACCGTGGCCCGCCGCGGTGGCATCGTGGTTCTGCCGCAGGATCTGCCCATCCCG
GCGGTGCACCAAACCGTGGAGTTCATCAAGAGCCGCGACCTGGTGCTAGACACGCCGGTGACGCTGGCCCCCGAGGATTC
GGTATCCGATGCGATCGCGTTGATCCACAAACGTGCCCATGGGGTCGCCGTTGTGGTCTCCGAGGGCCGCCCAATCGGCT
TGGTGACCGAAGCGTCCTGCGTGGGCGTGGACCGCTTCGCCCGGGTGCGCGATATCGCCGCCCTGGACTTTGTCAGCGCT
CCGGTGGGCACCGAGCCGCGAAAGGTCTTCGATCTGCTCGAGCACTCGCCCATCGAGGTTGCGGTGCTGACCCGGCCCGA
TGGCACGCTCGCCGGCGTGCTGAGCCGGACCGGGGCGATCCGCGCCGGGATCTACACGCCGGCCACCGACGCGGCCGGCC
GGCTGCGCATCGCGGCGGCCGTCGGTATCAATGGCGACGTGGCCGCCAAAGCGGGCGCCCTGGCCGAGTCAGGGGTGGAC
CTGCTGGTCATCGACACCGCCCACGGGCACCAGGTCAAGACACTGGATGCGATCAGTGCGGTCGCATCGCTGGATCTGGG
CCTTCCGTTGGCGGCGGGCAACGTGGTGTCTGCCGAGGGCACGCGGGACCTTCTGGGCGCCGGTGCCGACATCGTCAAGG
TGGGCGTTGGTCCCGGCGCCATGTGCACGACCCGGATGATGACCGGTGTCGGGCGGCCGCAGTTTTCCGCCGTGCTCGAA
TGCTCCGCTGCGGCAAGGGAGCTTGGCGGGCACGTATGGGCCGACGGCGGGATCCGTCATCCTCGCGACGTCGCACTGGC
GCTGGCAGCAGGCGCGTCCAACGTGATGATCGGATCCTGGTTCGCGGGCACCTATGAGTCCCCCGGCGATCTCATGCGCG
ACCGCGAAGACCAGCCCTACAAGGAGAGCTACGGCATGGCTTCCAAGCGTGCGGTAGTCGCTCGGACCACCACCGACAGC
GCGTTCGATCGGGCCCGAAAGTCGCTGTTCGAGGAAGGCATTTCGACGTCGCGGATGGGGCTCGACCTCGATCGCGGCGG
AGTGGAGGACTTGATCGACCACATCACATCCGGCGTGCGCAGCACTTGCACCTACGTCGGCGCGTCGAATCTGGCCGAAC
TTCATGAACAGGTGGTCATCGGCGTGCAGTCAGCGGCCGGCTTTGCCGAGGGGCATCCCCTACCCGCCGGCTGGTGA

Protein sequence :
MRFLDGHRPGYDLTYNDVFIMPNRSLVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVVLPQDLPIP
AVHQTVEFIKSRDLVLDTPVTLAPEDSVSDAIALIHKRAHGVAVVVSEGRPIGLVTEASCVGVDRFARVRDIAALDFVSA
PVGTEPRKVFDLLEHSPIEVAVLTRPDGTLAGVLSRTGAIRAGIYTPATDAAGRLRIAAAVGINGDVAAKAGALAESGVD
LLVIDTAHGHQVKTLDAISAVASLDLGLPLAAGNVVSAEGTRDLLGAGADIVKVGVGPGAMCTTRMMTGVGRPQFSAVLE
CSAAARELGGHVWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDREDQPYKESYGMASKRAVVARTTTDS
AFDRARKSLFEEGISTSRMGLDLDRGGVEDLIDHITSGVRSTCTYVGASNLAELHEQVVIGVQSAAGFAEGHPLPAGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 1e-136 58
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 5e-137 58
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-136 57
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-136 57