Gene Information

Name : ureG (MUL_3027)
Accession : YP_906750.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Virulence
Product : urease accessory protein UreG
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0378
EC number : -
Position : 3352590 - 3353261 bp
Length : 672 bp
Strand : -
Note : cytoplasmic protein; UreG is required for functional incorporation of the urease nickel metallocenter. it is not known whether UreG binds GTP or some other nucleotide.

DNA sequence :
ATGGCCAAGCATTCCCATGATCACACCCACGATCATCACGACCGGCCACGGCGGGTTCGAAAGCCGGGGGAGCCGTTGCG
GATCGGGGTCGGGGGCCCAGTTGGATCCGGCAAGACCGCACTGGTGGCGGCGATATGTCGGCAGTTGCGAGACGAGCTGT
CGCTCGCGGTGCTGACCAATGACATCTACACCACCGAGGACGCCGACTTTCTGCGCAAGCATGCGGTATTGCCAGACAGC
CGGATAATCGCGGTGCAAACCGGTGGCTGTCCGCACACCGCGATCCGCGACGACATCACCGCCAACCTGGATGCGATCGA
CGACTTGATCGCCGCACACGACGCGCTGGACTTGATCTTGGTCGAATCCGGTGGCGACAACCTCACCGCCACCTTCTCGT
CGGGCCTGGTGGATGTGCAGATCTTCGTCATCGATGTAGCCGGCGGCGACAAGGTTCCCCGCAAGGGCGGGCCCGGTGTG
ACCTTTTCAGACTTGTTGGTGGTCAACAAGACCGATCTGGCCCCGTTGGTGGGCGCCGATCTGAAGGTGATGGCTCGCGA
CGCCGAAGCGGTACGCGACGGACGTCCGACCGTGTTGCAGTCGTTGACCGAGGACCCCGCCGCGACGAAGGTACTGGACT
GGGTGCGCAGTCAGTTGGCCGCCGCAGGCTGA

Protein sequence :
MAKHSHDHTHDHHDRPRRVRKPGEPLRIGVGGPVGSGKTALVAAICRQLRDELSLAVLTNDIYTTEDADFLRKHAVLPDS
RIIAVQTGGCPHTAIRDDITANLDAIDDLIAAHDALDLILVESGGDNLTATFSSGLVDVQIFVIDVAGGDKVPRKGGPGV
TFSDLLVVNKTDLAPLVGADLKVMARDAEAVRDGRPTVLQSLTEDPAATKVLDWVRSQLAAAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureG YP_005682171.1 urease accessory protein UreG Not tested PiCp 7 Protein 3e-44 57
ureG YP_005684263.1 urease accessory protein UreG Not tested PiCp 7 Protein 3e-44 57
ureG YP_003784322.1 urease accessory protein Not tested PiCp 7 Protein 3e-44 57
ureG YP_005686355.1 urease accessory protein UreG Not tested PiCp 7 Protein 3e-44 57
ureG_2 NP_287091.1 urease accessory protein G Not tested TAI Protein 2e-35 56
ureG NP_286683.1 urease accessory protein G Virulence TAI Protein 2e-35 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureG YP_906750.1 urease accessory protein UreG VFG0274 Protein 1e-44 55