Gene Information

Name : smpB (MUL_2407)
Accession : YP_906231.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2690078 - 2690584 bp
Length : 507 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAGCGCAGTCGAAGCAGGCGAAACCGTCCGGCAAGCAGGGTGGCAAGAAGATCATCGCCACCAATCGCAAGGCTCG
GCACAACTACTCGATCATCGAGGTGTTCGAGGCCGGTGTCGCACTGCAGGGGACCGAGGTGAAGAGCCTGCGGGAGAGGC
ACGCGTCGCTGGTCGACGCCTTCGCCACCGTCGACGACGGCGAAGTCTGGCTGCGCAACCTGCACATCCCGGAGTACCTG
CACGGCACCTGGACCAACCACGAACCGCGGCGCAACCGCAAGCTGCTGTTGCATCGCCGCCAGATCGACACCCTGTTCGG
CAAGATTCGCGAAGGCAATTTCGCGCTGGTTCCGCTGTCGATGTATTTCCTCGACGGCAAGGTCAAGGTCGAACTCGCGT
TGGCGCGCGGTAAGCACGCCCACGACAAGCGTCAGGACCTGGCCCGGCGTGATGCCCAGCGTGAGGTGATTCGCGAACTG
GGTCGCCGGGCCAAGGGCATGGGCTGA

Protein sequence :
MAAQSKQAKPSGKQGGKKIIATNRKARHNYSIIEVFEAGVALQGTEVKSLRERHASLVDAFATVDDGEVWLRNLHIPEYL
HGTWTNHEPRRNRKLLLHRRQIDTLFGKIREGNFALVPLSMYFLDGKVKVELALARGKHAHDKRQDLARRDAQREVIREL
GRRAKGMG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-49 65
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-30 49
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-23 41