Name : thyA (MUL_2178) Accession : YP_906057.1 Strain : Mycobacterium ulcerans Agy99 Genome accession: NC_008611 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 2430948 - 2431748 bp Length : 801 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : GTGCCGATCGCGACGCCTTACGAGGATCTGTTGCGCAGGGTGCTCGAAACGGGCACCGCCAAATCCGACCGCACCGGCAC CGGGACCCGCAGCCTGTTCGGCCAGCAGATCCGGTACGACCTCGGTTGCGGTTTCCCCTTGCTGACCACCAAGAAGGTGC ACTTCAAGTCGGTCGTTTATGAGTTGCTGTGGTTTCTGCGCGGCGACTCCAACGTGGGCTGGTTGCAGCAGCACGGTGTG ACCATCTGGGACGAATGGGCCAGCGAAACAGGCGATCTCGGCCCAATCTACGGAGTTCAGTGGCGATCCTGGCCGACTCC GTCGGGTGAGCACATCGACCAGATCAGTGCCGCATTGGAACTGCTGCGTACCGACCCCGATTCGCGGCGCATCATCGTGT CGGCCTGGAATGTCGGCCAGATCCCGCAAATGGCGCTGCCGCCGTGTCACGCCTTTTTCCAGTTCTACGTCGCCGACGGC CGCCTGAGCTGCCAGCTGTATCAGCGCAGTGCCGACCTGTTTCTGGGGGTGCCTTTCAACATCGCCAGCTACGCCTTGCT CACCCACATGATGGCCGCTCAGGCCGGTCTTTCGGTCGGCGAGTTCATCTGGACCGGCGGCGATTGCCACATCTATGACA ACCACGTCGAACAGGTCACCGAGCAACTGCGTCGCGAGCCTCGGCCCTATCCGAAACTAAGCTTGTCGCAACGGGATTCG ATCTTCGACTACACCTACGAGGACGTCGTCGTGCAGGATTATGATCCCCATCCCGCGATCAAAGCTCCCGTCGCTGTATG A Protein sequence : MPIATPYEDLLRRVLETGTAKSDRTGTGTRSLFGQQIRYDLGCGFPLLTTKKVHFKSVVYELLWFLRGDSNVGWLQQHGV TIWDEWASETGDLGPIYGVQWRSWPTPSGEHIDQISAALELLRTDPDSRRIIVSAWNVGQIPQMALPPCHAFFQFYVADG RLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVTEQLRREPRPYPKLSLSQRDS IFDYTYEDVVVQDYDPHPAIKAPVAV |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 6e-96 | 73 |