Gene Information

Name : nrdF (MUL_1883)
Accession : YP_905816.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 2084047 - 2085021 bp
Length : 975 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
GTGACTGGAAATGCAAAGCTGATCGACCGCGTCTCCGCGATCAACTGGAACCGCGTCCAAGACGAGAAAGACGCCGAGGT
CTGGGACCGGTTGACCGGCAACTTCTGGCTGCCAGAGAAGGTCCCGGTATCCAACGACATCCCCTCCTGGGGCACGCTGA
CCGCCGGTGAAAAGCAGCTGACCATGCGGGTGTTCACGGGTCTGACGATGCTGGACACGATTCAGGGCACCGTGGGTGCG
GTCAGCTTGATCCCCGACGCGCTGACTCCCCACGAGGAGGCGGTGCTGACCAACATCGCGTTCATGGAGTCGGTGCACGC
CAAGAGCTACAGCCAGATTTTCTCCACCCTGTGCTCGACCGCCGAGATTGACGACGCGTTCCGCTGGTCGGAGGAAAACT
CCAACCTGCAGCGCAAGGCGGAGATCGTGCTCGAGTACTACCGGGGCGATGACCCGCTCAAGCGCAAGGTGGCCTCCACG
CTGCTGGAAAGCTTCCTGTTCTACTCGGGCTTCTACCTGCCGATGTACTGGTCGAGCCGGGCCAAGCTGACCAACACGGC
TGACATGATCCGGCTGATCATCCGCGATGAGGCCGTGCACGGCTACTACATCGGCTACAAGTTCCAGCGCGGGCTTGCGG
CCGCCGACGAGGCCCGGCGTACCGAGCTCAAGGACTACACCTACGAGCTGCTCTTCGAGCTATATGACAACGAAGTCGAG
TACACCCAGGATCTCTACGACGAGGTCGGGCTGACCGAGGATGTCAAGAAGTTCTTGCGCTACAACGCAAACAAGGCGTT
GATGAACCTCGGCTACGAGGCCCTGTTCCCGCGCGATGAGACCGACGTGAACCCGGCGATCCTTTCGGCGCTGTCGCCCA
ATGCCGACGAGAACCACGACTTCTTCTCCGGCTCGGGGTCGAGCTACGTGATCGGCAAGGCCGTGGCCACTCAAGACGAG
GACTGGGACTTCTAG

Protein sequence :
MTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGA
VSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQRKAEIVLEYYRGDDPLKRKVAST
LLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDNEVE
YTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVATQDE
DWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-116 74