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Name : tkt (MUL_1844) Accession : YP_905786.1 Strain : Mycobacterium ulcerans Agy99 Genome accession: NC_008611 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 2039913 - 2042015 bp Length : 2103 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : GTGACCACTCTCGAGGAGATCTCTGCGCTCACCCAACCGCGCCATCCCGACGACTGGACCGAGATCGATTCGGCTGCGGT CGACACGGCCCGAGTGCTGGCAGCCGACGCCGTGCAAAAGGTCGGCAATGGACACCCGGGAACGGCGATGAGCCTGGCCC CGCTGGCCTACACGTTGTTTCAGCGCGCGATGCGCCACGACCCCAGCGACACCACTTGGTTGGGCCGGGACCGGTTCGTC CTGTCCTGCGGACACAGCAGCCTGACCCTCTACATACAGCTCTACCTGGGCGGCTTCGGGCTTGAATTGTCCGACATCGA GTCGCTGCGCACCTGGGGGTCCAAGACTCCCGGGCATCCCGAGTTCCGCCACACCGCCGGGGTGGAGATCACCACGGGTC CGCTGGGCCAGGGCCTGGCTTCAGCGGTGGGCATGGCTATGGCGGCACGCTATGAGCGTGGCCTGTTCGACCCCGACGCC GAACCCGGAACCAGCCCCTTCGACCATCACATTTACGTGATCGCCTCCGACGGTGACATCGAAGAGGGAGTCACCTCCGA GGCGTCGTCTCTTGCGGCCGTTCAACAGCTGGGCAACCTCATCGTCTTCTACGACCACAACAAGATCTCGATCGAGGACG ACACCAACATCGCGCTGTGCGAAGACACCGCTGCTCGCTACCGCGCCTACGGCTGGCACGTGCAAGAGGTGGAGGGCGGC GAGAACGTCACCGGCATCGAGGAGGCGATCGCCAACGCGAAGGCGGTCACCGATCGGCCCTCGTTCATCTCGCTGCGCAC CATCATCGGCTACCCGGCGCCGAACATGATGAACACGGGCAAGGTGCATGGTGCGGCGCTTGGTGACGAGGAAGTGGCGG CCGTCAAGACAGTCCTCGGATTCGATCCCAACAAGGCGTTCGAAGTGCGCGAAGACGTCATCACGCACACCCGCGGGATG GTGGCGCGCGGCAAGGAGGCGCACGAAAGCTGGCAGGCCGACTTTGAGGCCTGGGCGCAGCGGGAACCGCAGCGCAAGGC CTTGCTGGACCGTCTGACGGCCCAGCAGCTGCCCGACGGCTGGGATGCCGACATGCCGCGCTGGGAGCCCGGTTCCAAAG CACTGGCCACGCGGGCAGCGTCCGGACAGGTGCTGGCCGCGATCGGCCCCAAACTCCCCGAGTTGTGGGGCGGTTCGGCT GACCTTGCCGGCAGCAACAACACCACCATCAAGGGCGCGGACTCATTCGGCCCGCCAGCGATCTCTATCGATGACTACAC CGCGCACTGGTACGGCCGCACGCTGCACTTCGGTGTTCGCGAGCACGCGATGGGCGCCATCCTCTCCGGGATCGCGCTGC ACGGACCCACCCGCGCCTACGGTGGCACGTTCCTGCAGTTCTCCGATTACATGCGCCCGGCAGTGCGGCTGGCGGCACTG ATGGACATCGACCCCATTTACGTCTGGACCCACGATTCGATCGGACTGGGTGAAGACGGCCCGACCCACCAGCCGATCGA GCACCTTTCGGCGTTGCGCGCGATCCCCCGGCTCGCGGTGGTGCGCCCGGCCGACGCCAATGAGACGGCGTACGCCTGGA GCACGATCCTGGCCCGGGGCGCCACCAGCGGTCCGGTCGGGCTGATCCTGACCCGGCAGGGAGTGCCGGTGCTAGCGGGC ACCAACGCCGAGGGCGTTGCCCGCGGTGGCTACGTGCTCAGCGATGGCGCCGATGGTGACTCGTCCGAAGACCCCGACGT CGTTTTGATCGCCACCGGTTCCGAGGTGCAGCTTGCGGTCGAAGCACGGAAGTTGTTGGCGGATAACGACATCATCGCGC GAGTGGTATCGATGCCGTGCGTGGAGTGGTTTGAGTCCCAGCCTGAGGAATACCGCGACAGTGTGTTGCCGCCGTCGGTT TCGGCCCGGGTGGCCGTCGAGGCCGGCATCGCACAGTGCTGGCACAAGCTGGTCGGTGACACCGGCAAGATCGTTTCGAT CGAGCACTACGGAGAGTCCGCCGACTACAAGACATTGTTCCGCGAGTACGGCTTTACCGCCGAAGCTGTTGCCGCTGCCG CGGAACGAGCATTGGAAAATTGA Protein sequence : MTTLEEISALTQPRHPDDWTEIDSAAVDTARVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRAMRHDPSDTTWLGRDRFV LSCGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTAGVEITTGPLGQGLASAVGMAMAARYERGLFDPDA EPGTSPFDHHIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNKISIEDDTNIALCEDTAARYRAYGWHVQEVEGG ENVTGIEEAIANAKAVTDRPSFISLRTIIGYPAPNMMNTGKVHGAALGDEEVAAVKTVLGFDPNKAFEVREDVITHTRGM VARGKEAHESWQADFEAWAQREPQRKALLDRLTAQQLPDGWDADMPRWEPGSKALATRAASGQVLAAIGPKLPELWGGSA DLAGSNNTTIKGADSFGPPAISIDDYTAHWYGRTLHFGVREHAMGAILSGIALHGPTRAYGGTFLQFSDYMRPAVRLAAL MDIDPIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLAVVRPADANETAYAWSTILARGATSGPVGLILTRQGVPVLAG TNAEGVARGGYVLSDGADGDSSEDPDVVLIATGSEVQLAVEARKLLADNDIIARVVSMPCVEWFESQPEEYRDSVLPPSV SARVAVEAGIAQCWHKLVGDTGKIVSIEHYGESADYKTLFREYGFTAEAVAAAAERALEN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 1e-119 | 43 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 4e-122 | 43 |
