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Name : MUL_1416 (MUL_1416) Accession : YP_905426.1 Strain : Mycobacterium ulcerans Agy99 Genome accession: NC_008611 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 1522423 - 1523946 bp Length : 1524 bp Strand : + Note : cytoplasmic protein; interconversion aldehyde and acid [catalytic activity: an aldehyde + NAD+ + H2O = an acid + NADH] DNA sequence : ATGACCGTGTTTGCACGTCCGGGTTCGGCCGGGGCGCTGATGTCGTTTGAGTCCCGGTACGGAAATCTCATCGGGGGTGA GTGGGTTGCCCCGGCGCGGGGCCGTTACTTCGAAGACCTGACCCCGGTGACCGGCCAGCCATTTTGCGAGATACCGCGCT CTGATGAGGCCGATGTCGAGATGGCGCTCGACGCCGCACATGCGGCGGCCCCGGCCTGGGGCAAGATGGCCCCGGCCGAG CGAGCCGCGATCCTGAACAAGATCGCCGACCGGATCGATGAAAACAGGGCCGCGCTGGCGGTGGCCGAAGTCTGGGACAA CGGCAAACCGGTCCGAGAGGCAATAGCCGCTGACATCCCGCTGGCGGCGGATCACTTCCGCTACTTCGCAGCGGCGATCC GGGCCCAGGAAGGTTCGCTGTCGCAGATCGATCAGGACACGGTCGCGTACCAGTTTCACGAGCCGCTCGGGGTGGTGGGG CAGATCATTCCGTGGAACTTCCCGATCCTGATGGGTGCTTGGAAGCTGGCGCCGGCGCTGGCGGCCGGTAACGCGGTGGT GCTCAAACCCGCGGAGCAGACGCCCGCGTCGGTGCTGTACCTGATGTCGCTGATCGGCGACCTATTGCCGCCCGGGGTGG TCAACGTCGTCAATGGTTTCGGCGCCGAAGCGGGCAGGCCGCTGGCGTCCAGCAACCGAATTGCCAAGGTCGCGTTCACC GGAGAGACCACCACCGGGCGCCTGATCATGCAGTACGCCTCACAAAACCTGATCCCGGTAACCCTGGAACTCGGCGGCAA GAGCCCCAACATCTTCTTTTCTGATGTGATGGCCAAGCCCGACGACTTCCAGGACAAGGCGCTGGAGGGTTTCACGATGT TCGCCCTCAACCAGGGCGAGGTGTGTACCTGTCCGTCGCGCAGCCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG CTGGCGGCGATCCGGACCAAGGCGGTTCGGCAGGGCGATCCCTTGAACATCGAGACGATGCTGGGGTCACAGGCCTCCAA CGACCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGGAAGAGGGCGCCAAGGTCATTACCGGCGGCGAGCGCG CCGAACTCGGCGGTGACCTGTCCGGCGGCTTTTACATGCAGCCGACGATCTTCAGCGGCACCAACAAGATGCGGATCTTC CAGGAGGAGATATTCGGTCCGGTGGTGGCGGTCACGCCGTTCACCGACTACGACGACGCGATGGGTATCGCCAACGACAC CCTCTACGGGTTGGGGGCGGGGGTGTGGAGCCGCGACGGCAACACGGCCTACCGGGCCGGCCGGGACATCCAGGCGGGCC GGGTGTGGGTCAACTGCTATCACGTCTACCCGGCGCACTCGGCGTTCGGTGGCTACAAGCAGTCCGGCATTGGCCGGGAA GGCCATCAGAAGATGCTGGGCCACTATCAGCAGACCAAGAACCTGTTGGTGTCCTACTCGGATAAGCCTTTGGGGTTGTT CTGA Protein sequence : MTVFARPGSAGALMSFESRYGNLIGGEWVAPARGRYFEDLTPVTGQPFCEIPRSDEADVEMALDAAHAAAPAWGKMAPAE RAAILNKIADRIDENRAALAVAEVWDNGKPVREAIAADIPLAADHFRYFAAAIRAQEGSLSQIDQDTVAYQFHEPLGVVG QIIPWNFPILMGAWKLAPALAAGNAVVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGRPLASSNRIAKVAFT GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAKPDDFQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE LAAIRTKAVRQGDPLNIETMLGSQASNDQLEKVLSYIEIGKEEGAKVITGGERAELGGDLSGGFYMQPTIFSGTNKMRIF QEEIFGPVVAVTPFTDYDDAMGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHVYPAHSAFGGYKQSGIGRE GHQKMLGHYQQTKNLLVSYSDKPLGLF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-133 | 59 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-139 | 58 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-139 | 58 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 1e-139 | 58 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 5e-139 | 58 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 1e-63 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| MUL_1416 | YP_905426.1 | aldehyde dehydrogenase | VFG0082 | Protein | 7e-134 | 59 |
