Gene Information

Name : glnA1 (MUL_1340)
Accession : YP_905364.1
Strain : Mycobacterium ulcerans Agy99
Genome accession: NC_008611
Putative virulence/resistance : Virulence
Product : glutamine synthetase GlnA1
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : -
Position : 1444670 - 1446106 bp
Length : 1437 bp
Strand : -
Note : Detected in the membrane fraction by proteomics (LC- MS/MS); cytoplasmic protein; involved in glutamine biosynthesis [catalytic activity: ATP + L-glutamate + NH(3) = ADP + glutamine + orthophosphate]

DNA sequence :
GTGACGGATAAGACGCCCGACGACGTCTTCAAACTCGCCAAAGACGACGGCGTCGAGTTTGTCGATGTGCGGTTCTGCGA
TCTGCCCGGTGTCATGCAGCACTTCACGATTCCGATCTCCTTCTTCGATGAGGCCGTTTTCGAGGACGGCCTGGCCTTCG
ACGGCTCCTCGATCCGCGGATTCCAGTCGATCCACGAGTCCGACATGCTCCTGCTCCCGGACCCCGATACCGCGATCATC
GACCAGTTCCGCGAAGCCAAGACGCTGAACCTGAACTTCTTTGTGCATGACCCGTTCACCCTTGAGCCCTACTCCCGCGA
CCCGCGCAACGTCGCCCGCAAGGCCGAGAACTACCTGATCAGCACCGGCATCGCCGACACCGCCTACTTCGGCGCCGAGG
CCGAGTTCTACATTTTCGACTCGGTGGCCTTCGACTCGCGCACCAACGGGTCGTTCTACGAGGTGGACGCCATCTCCGGG
TGGTGGAACACCGGCGCAGCCAACGAAGCCGACGGCGGCCCCAACCTCGGCTACAAGGTCCGCCCCAAGGGCGGGTACTT
CCCGGTGGCGCCGGTCGACCACTACGTCGACCTGCGCGACAAGATGCTGACCAACCTGATCAACGCCGGCTTCAGCCTGG
AAAAGGGTCACCACGAGGTGGGCACCGGCGGGCAGGCCGAGATCAACTACAAGTTCAACACGCTGCTGCACGCCGCGGAC
GACATGCAGCTCTACAAGTACATCGTCAAGCAGACCGCATGGCAGGCCGGCAAGACCGTGACCTTCATGCCCAAGCCGCT
CTTCGGTGACAACGGATCGGGTATGCACACCCACCAGTCGCTGTGGAAGGACGACACCCCGATGATGTACGACGAGACCG
GGTACGCCGGCCTGTCGGACACGGCTCGCCACTACATCGGTGGCCTGTTGCACCACGCGCCTTCGCTGCTGTCCTTCACC
AACCCCACGGTGAACTCCTACAAGCGGCTGGTGCCCGGCTACGAGGCCCCGATCAACCTGGTCTACAGCCAGCGCAACCG
CTCGGCCTGTGTGCGTATCCCGATCACCGGCAGCAACCCGAAGGCCAAGCGCCTCGAGTTCCGCTGCCCCGACTCGTCGG
GCAACCCGTACCTGGCGTTCGCGGCGATGTTGATGGCCGGCCTGGACGGCATCAAGAACAAGATCGAGCCGCAGGCGCCG
GTCGACAAGGACCTCTACGAGCTGCCGCCGGAGGAAGCCGCAAACATCCCGCAGGCCCCGACCCAGCTGGCTGCGGTGAT
CGACCGGCTCGAGGCTGACCACGAATACCTCACGGAGGGTGGCGTATTCACCCCCGACCTGATCGAGACGTGGATCAGCG
TCAAGCGCGAGAACGAGATCGAGCCGGTCAACCTGCGGCCGCACCCGTACGAGTTCGCGCTCTACTATGACTGCTAG

Protein sequence :
MTDKTPDDVFKLAKDDGVEFVDVRFCDLPGVMQHFTIPISFFDEAVFEDGLAFDGSSIRGFQSIHESDMLLLPDPDTAII
DQFREAKTLNLNFFVHDPFTLEPYSRDPRNVARKAENYLISTGIADTAYFGAEAEFYIFDSVAFDSRTNGSFYEVDAISG
WWNTGAANEADGGPNLGYKVRPKGGYFPVAPVDHYVDLRDKMLTNLINAGFSLEKGHHEVGTGGQAEINYKFNTLLHAAD
DMQLYKYIVKQTAWQAGKTVTFMPKPLFGDNGSGMHTHQSLWKDDTPMMYDETGYAGLSDTARHYIGGLLHHAPSLLSFT
NPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRCPDSSGNPYLAFAAMLMAGLDGIKNKIEPQAP
VDKDLYELPPEEAANIPQAPTQLAAVIDRLEADHEYLTEGGVFTPDLIETWISVKRENEIEPVNLRPHPYEFALYYDC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 9e-91 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA1 YP_905364.1 glutamine synthetase GlnA1 VFG1399 Protein 0.0 91