Gene Information

Name : hemC (Rmag_0783)
Accession : YP_903979.1
Strain : Candidatus Ruthia magnifica Cm
Genome accession: NC_008610
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 829347 - 830261 bp
Length : 915 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAACAAAACTCTAAAAATTGCAACTCGACAATCTCCATTGGCGTTATGGCAAGCTCAGAATGTTAAAATTAGACTGGA
AAAACACCATCCTGATCTAACAGTTATTCTAGTGGAAATGACAACTAAGGGTGATCAAATTCTAAACTCACCTTTGTCAA
AAATTGGTGGTAAGGGTTTGTTTATTAAAGAATTAGAAGTTAGTATGATGAAGGGTATAACTGATATTGCCGTGCATTCT
ATGAAAGATGTGCCTTATGAAATACCACAAGGATTTAAGTTAGGGGCAATTTTAAAACGTGAAAATCCCTTTGATGCCTT
TGTTTCCAATGATTTTTCAAGTATTGATGATTTACCACAAAATGCTAAAGTTGGTACTTGTTCAATACGTCGTATTGTGC
AACTTAAAGCTATTCGACCTGATTTAAAAATTCTAGATTTACGTGGCAATGTTAATACTCGATTAAAAAAATTAGATAAA
GGTGGATTTGATGGCATTATTCTTGCTTGTGCAGGGCTTATTCGTCTAGGATTTGAGAGTCGAATCAAGCAACAAATTTC
TGACCAGCAAAGCTTGCCTGCCGTAGGGCAAGGAGTAGTGGGTATTGAAATTCGTGAAAACGATACAGAAATTTTAGATT
TAATTAAGCCTTTGATTGATGTTGAAACCACCTACATGGTAAGCGCAGAGAGAGCTATGAATGCACGCCTTGAGGGTGGT
TGTTCGGTACCGATTGCAGGTTTTGCTTTGATTGATAATGAGCAAATAATGTTAACAGGTTTGGTGGGTAATGTTGATAC
TGGTGTGATATTAAAAGAACAGATTTTGAGTCATGTTTCTCAAGCAGAGGCTTTGGGTGTTGAATTGGCAAATAAACTCA
TATCATTAGGTGCTAAAGATATTTTAAAAAACTAA

Protein sequence : 
MNKTLKIATRQSPLALWQAQNVKIRLEKHHPDLTVILVEMTTKGDQILNSPLSKIGGKGLFIKELEVSMMKGITDIAVHS
MKDVPYEIPQGFKLGAILKRENPFDAFVSNDFSSIDDLPQNAKVGTCSIRRIVQLKAIRPDLKILDLRGNVNTRLKKLDK
GGFDGIILACAGLIRLGFESRIKQQISDQQSLPAVGQGVVGIEIRENDTEILDLIKPLIDVETTYMVSAERAMNARLEGG
CSVPIAGFALIDNEQIMLTGLVGNVDTGVILKEQILSHVSQAEALGVELANKLISLGAKDILKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-78 57
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-78 57