Gene Information

Name : thyA (Rmag_0616)
Accession : YP_903836.1
Strain : Candidatus Ruthia magnifica Cm
Genome accession: NC_008610
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 670751 - 671545 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGAAACAATACTTAGATTTTTTAAGGCTGGTTAAAAATACTGGCACCAATAAAACCGATAGAACAGGCATAGGAACAAC
CAGCTTGTTTGGATACCAAATGCGTTTTGATTTATCTGATGGATTTCCACTTATAACCACCAAACGTGTACACTTACCTT
CAGTTGTGCACGAGTTGTTGTGGTTTCTTAGCGGTGCTACTAATATTAAATACTTACAAGAAAATGGTGTGCGAATTTGG
AATGAATGGGCAGATAAAAACGGGGATTTAGGCCCAATTTATGGTGTACAGTGGCGAAATTGGCAAAATGTTAGAGGTGA
AAGTATTGACCAAATTATGCAAGTGATAGAGCAAATTAAGAATACGCCAGATTCTCGTAGAATTATTGTTTCAGCTTGGA
ATGTTGGTGAATTGGAAAATATGGCATTACCACCTTGTCATGCATTTTTTCAGTTTTACGTTGCGCTTGGGAAGCTATCT
TGTCAGTTGTATCAAAGAAGTGCAGATGTTTTCCTTGGTGTACCATTTAATATTGCTTCATATGCATTACTAACCCACAT
GATGGCGCAACAGTGTGATTTGGAAGTGGGTGATTTTATTTGGAGTGGCGGTGATTGTCATATTTATTCCAATCATACTA
AACAAGTAGAAATACAATTAGCTCGCACTCCAAAAACACTAGCAACACTTAAAATCAATAACAAGCCTGACAGTATTTTT
GATTACAATTTTGAGGATTTTGAGTTTATAAATTACGTGTTTGATGCATACATTAAAGCGACAGTTGCAATTTAA

Protein sequence :
MKQYLDFLRLVKNTGTNKTDRTGIGTTSLFGYQMRFDLSDGFPLITTKRVHLPSVVHELLWFLSGATNIKYLQENGVRIW
NEWADKNGDLGPIYGVQWRNWQNVRGESIDQIMQVIEQIKNTPDSRRIIVSAWNVGELENMALPPCHAFFQFYVALGKLS
CQLYQRSADVFLGVPFNIASYALLTHMMAQQCDLEVGDFIWSGGDCHIYSNHTKQVEIQLARTPKTLATLKINNKPDSIF
DYNFEDFEFINYVFDAYIKATVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-85 65