Gene Information

Name : guaA (Ppro_2010)
Accession : YP_901676.1
Strain : Pelobacter propionicus DSM 2379
Genome accession: NC_008609
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2157679 - 2159241 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAACTGACATCCACAGCCAGAAGATCCTGATCCTCGATTTCGGCTCCCAGTACACCCAGCTGATCGCCCGGCGGGT
GCGCGAGGCCCACGTGTTCTGCGAACTGCACCCCTTTGACATGGAGATGGCGGCCATCCGCGCCTTCAATCCCTCGGGCA
TCATCCTGTCCGGCGGCCCCAAATCGGTCTACGAGCCGGGAGCGCCGGCAGTTGCCGAGGAGCTGTTCGAGCTGGGAGTT
CCGGTGCTGGGGATCTGCTACGGCATGCAGCTCATGAGCCGCCACTTCGGCGGAGAAGTGGTGCCTGCCGGCAAGCGCGA
GTTCGGCCACGCCGAGTTGCTTTGTTCCGGCCAGCCCGGCCAGCTGTTCGACGGCTTCTTCGTGGGGGGGGCGAGCCCGG
TCTGGATGAGTCATGGCGACCACGTCTCCCGCGTGCCGGACGGATTCCAGGTGGTGGCCTACACGGAGAACGCCCCGGTC
TGCGCCATCCAGGATGTGAGCCGCAACCTGTACGGGGTGCAGTTCCATCCCGAGGTCAACCACACCCCCCGCGGCGACCA
GCTGATCGACACCTTTGTGCGTGCCATCTGCGGCTGCACCGGTCACTGGACACCCGGCCAGATCATCGAGGATGCCGTTA
CCCGCATCCAAGAACAGGTGGGCAGCGAACGGGTGATCCTGGGGCTTTCCGGCGGGGTGGACTCGTCGGTGGCTGCCGCA
TTGATCCATCGGGCCATTGGCGACCAGCTGACCTGCGTCTTCGTGGACAACGGCCTGCTGCGCCTGGAGGAGGGTGACCA
GGTGATGCGCACCTTTGCCGAAAACCTGGGGGTCAAGGTGATCCGGGTCAACGCCGAGGAGCGTTTCCTAAGCGCCCTGG
CCGGGGAGAGCGATCCGGAGAAAAAGCGCAAGATCATCGGCAGCCTGTTCGTGGAGATCTTCGACGAGGAGTCCAACCGC
ATCGAGGACGCCCGCTGGCTGGCCCAGGGGACCATCTACCCGGACGTTATCGAGTCGGCCGGGGCCAAGACCGGCAAGGC
CCACAACATCAAGAGCCACCACAACGTGGGCGGGCTTCCGGAGTACATGAAGCTCAAGCTCCTGGAACCGCTGCGCGAAC
TGTTCAAGGACGAGGTGCGCGCCATCGGCGAGGAGCTGGGGCTCCCCCATCAGATGGTCTGGCGCCACCCTTTCCCCGGG
CCGGGACTGGCCGTGCGCATCCTGGGAGAGGTGAAGAAGGAGTACGCCGACATCCTTCGCAGGGCGGATGCCATCTTCAT
CGAGGAGCTCTACTCCTCCGACCATTACCACAAGATCAGCCAGGCTTTTGCCGTGTTCCTGCCGGTGAAGAGCGTGGGGG
TCATGGGCGACGGCCGCACCTACGAGTATGTGGTGGCCCTGCGGGCGGTGGAAACCAAAGACTTCATGACCGCCAGCTGG
TACCCGCTCCCCTACGAAGACATGGCCCGCATCAGTGCTAGGATCATCAACGAGGTCAAGGGGGTCAACCGGGTGGTGTA
CGACATCTCCAGCAAGCCGCCCGCCACCATCGAGTGGGAGTGA

Protein sequence :
MKTDIHSQKILILDFGSQYTQLIARRVREAHVFCELHPFDMEMAAIRAFNPSGIILSGGPKSVYEPGAPAVAEELFELGV
PVLGICYGMQLMSRHFGGEVVPAGKREFGHAELLCSGQPGQLFDGFFVGGASPVWMSHGDHVSRVPDGFQVVAYTENAPV
CAIQDVSRNLYGVQFHPEVNHTPRGDQLIDTFVRAICGCTGHWTPGQIIEDAVTRIQEQVGSERVILGLSGGVDSSVAAA
LIHRAIGDQLTCVFVDNGLLRLEEGDQVMRTFAENLGVKVIRVNAEERFLSALAGESDPEKKRKIIGSLFVEIFDEESNR
IEDARWLAQGTIYPDVIESAGAKTGKAHNIKSHHNVGGLPEYMKLKLLEPLRELFKDEVRAIGEELGLPHQMVWRHPFPG
PGLAVRILGEVKKEYADILRRADAIFIEELYSSDHYHKISQAFAVFLPVKSVGVMGDGRTYEYVVALRAVETKDFMTASW
YPLPYEDMARISARIINEVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-133 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-119 50