Gene Information

Name : Ppro_1613 (Ppro_1613)
Accession : YP_901286.1
Strain : Pelobacter propionicus DSM 2379
Genome accession: NC_008609
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1728674 - 1729441 bp
Length : 768 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAACATCACAGCAGTCATTCCAGCCCGCTTTGCTTCTGTGCGTTTTCCGGGCAAGGCGCTGGCCATCATCGACGGCAA
GCCGATGATCCAACATGTCTACGAGCGCACGGCACGGGCTTCACTGGTGGACTCGGTCATTATCGCTACCGATGACGAGC
GTATCCAGCAGGCGGTTTCGGTCTTCGGCGGTGTCTGTCGCATGACCCGCAATGACCACGAAACAGGAACCGATCGTCTG
GCCGAGGTGGCTGGGACGCTCTCCGCCGACATCATCGTCAATGTCCAGGGGGATGAGCCGCTGATCGCTCCCGAGATGAT
CGACCAGGCTATCCGCCCGCTCCTTGATGACCCGTCCCTGCGCATGGCTACACTCAAGAGCCGCATCCGCTGCCTGCACG
ATTTTTTGAGCCCCAATGTGGTCAAGGTGGTAACCGACCGGGACGGCAATGCGCTGTACTTCTCCCGCTCGCCCCTGCCG
TTCTTCCGGGACAAGTGGCAGGATCTCAAGGACGAGTCATTCGCCAGCGGGAAGCTGCTCTGCTACAAGCATGTGGGGCT
GTACGTCTATCGTCGTGATTTTCTGGTGGAGTTCGCCGCTATGGCGCCCACCTTTCTGGAAACTTCCGAGAAACTGGAGC
AGTTGCGAGCGCTGGAAAACGGCGCCCGTATCCGCGTCGTCGAGACTGAGTTTGAATCCATTGGTGTGGACACCCCCGAT
GACCTGGTCAAGGCCAGGGAGCGGTTCAGAGCCATTCAGTCCAAGTAA

Protein sequence :
MNITAVIPARFASVRFPGKALAIIDGKPMIQHVYERTARASLVDSVIIATDDERIQQAVSVFGGVCRMTRNDHETGTDRL
AEVAGTLSADIIVNVQGDEPLIAPEMIDQAIRPLLDDPSLRMATLKSRIRCLHDFLSPNVVKVVTDRDGNALYFSRSPLP
FFRDKWQDLKDESFASGKLLCYKHVGLYVYRRDFLVEFAAMAPTFLETSEKLEQLRALENGARIRVVETEFESIGVDTPD
DLVKARERFRAIQSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 5e-44 47
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 8e-44 47
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-44 47