Gene Information

Name : kdsB (FTN_0683)
Accession : YP_898329.1
Strain : Francisella novicida U112
Genome accession: NC_008601
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 726940 - 727692 bp
Length : 753 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGGCTAATATCCATATTGTAATTCCTGCTAGGCTTAAATCAACTCGTCTACCAAATAAAATGCTAGCAGATATTGCCGG
TAAGCCAATGATTCAGAGAGTCTATGAGCAAGTGGCTAAATCAAAGTTTGATAGCATAATAATAGCTACAGATTCGCAAA
AAATAAAAGATATCGCAGAGAGCTTTGGTGCAAAAGTAGTTTTGACAAGAGATGATCATCAATCAGGAACAGATAGAATA
GCAGAAGCAGTTACTAAATTAGGCTTTGCAGATGAAGACATTGTTGTAAATGTCCAAGGTGATGAGCCATTGATCCCTAT
TGAAAATATCGAGCAAGCTGCGCAGTTATTGATAGACAAATCAGAAGCTGTAGTCTCAACGTTGTGTGAAAAAATCACAG
ATGTAGAAGATATTTATAATCCTAATAATGTCAAAGTAGTTTTTGATAAAAATAACTATGCTTTATATTTTAGTAGAGCA
TCTATTCCTTTTGAAAGAGGTTTTTCTGAGAAAGAGCAGATTAATATTTCAGAATTTTTTAGACATATTGGTATATATGC
ATATCGAGTAGCTTTTTTAAAACATTATGCAGAACTTACAGTTTCACCAATTGAGAAATACGAAGCTCTTGAACAGCTAA
GAGTCTTATATAATGGTTACAAAATCGCTATTGAGCAATCAGCTAAATCAACTCCTGCTGGTGTTGATACATTGCAAGAT
TTAGAAAAAGTAAGGAGATTATTTAATGTTTAA

Protein sequence :
MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVAKSKFDSIIIATDSQKIKDIAESFGAKVVLTRDDHQSGTDRI
AEAVTKLGFADEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRA
SIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQD
LEKVRRLFNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-42 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 7e-42 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-42 43