Gene Information

Name : serS (FTN_0647)
Accession : YP_898294.1
Strain : Francisella novicida U112
Genome accession: NC_008601
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 684751 - 686031 bp
Length : 1281 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATGCTAAATATATTAAGGATAATTTACAACAAGTTGCTGAAAAGCTTGCAACTAGAGGTTATCAATTTGATAT
AGCCGAATTTGAAGCCCAAGAGCAAAAAAGAAGACATCTTCAAGAAAGAACTCAGGATCTACAATCACAACGTAATACTA
TTTCAAAAGAAATAGGTCAAAAAAAAGCTAAAGGTGAAGATACTAGTGATATCTTTGCTAAAGTTAATCAAATTAATGAA
GAACTAAAAATTATTGAAAAAGAGCTCAAAGACCTACAAGATACTATAAATCAAACACTATTATCAATGCCAAACCTTCC
TGCTGATGACGTCCCTGTTGGTAAAGATGAGAATGATAATGTAGAAATAAGAAGATGGGGAACTCCACGTGAGTTTCATC
CTGAAGCACCTGCAAAAGATCATGCTGATATTGGTGAAATCCTTAAAATGATTGATTTTAAAGCCGCTGCTAAAGTTACT
GGCAGCCGTTTTATGGTCCTGAAAAATAAGATTGCTAAACTACACCGCGCTCTATCACAGTTTATGCTTGATCTGCATAC
AGAAAAACATGGTTATGAAGAATTATATGTGCCATATCTAGTCAATAATGATAGTTTATATGGTACTGGACAATTACCAA
AATTTGCTGCTGATCTTTTTAAGCTTGAGGGAGATTTTGAATATAGTCTAATACCTACAGCAGAGGTGCCAATCACTAAT
CTAGTAAGGGATGAAATTTTAGATACAGAAACTTTACCTAGATACTATACAGCTCACACTCCTTGCTTTAGAAGTGAAGC
TGGTTCATATGGTCGTGATACTAAAGGTATGATTCGTCAACACCAGTTTGAGAAAGTCGAGTTAGTACATATCACTGCTG
CTGATAAAGGTGAAGAATCTCTAGAATTACTCACATCACATGCTGAAAAAGTCTTACAAAAACTTAACTTACCATATAGA
GTGATGAAACTGTGTACTGGTGATATGAGCTTTAGCGCTAAAAAAACTTATGATTTAGAAGTATGGCTCCCATCACAAAA
TACTTATAGAGAAATATCTTCATGTAGCTGGTGTGGAGATTTCCAAGCTCGTCGCATGAAAGCTCGACACAAAAATCCAA
GTATGAAGAAACCGGAATTAGTCCATACTCTAAATGGTTCTGGTTTGGCTGTAGGTAGAACATTATTAGCTATTATTGAA
AATTATCAACAAGAAGATGGTTCTATTATGGTTCCCGATGCTCTTATCAAGTATATGGGCGGAATTTCAGTTATTAAGTA
A

Protein sequence :
MLDAKYIKDNLQQVAEKLATRGYQFDIAEFEAQEQKRRHLQERTQDLQSQRNTISKEIGQKKAKGEDTSDIFAKVNQINE
ELKIIEKELKDLQDTINQTLLSMPNLPADDVPVGKDENDNVEIRRWGTPREFHPEAPAKDHADIGEILKMIDFKAAAKVT
GSRFMVLKNKIAKLHRALSQFMLDLHTEKHGYEELYVPYLVNNDSLYGTGQLPKFAADLFKLEGDFEYSLIPTAEVPITN
LVRDEILDTETLPRYYTAHTPCFRSEAGSYGRDTKGMIRQHQFEKVELVHITAADKGEESLELLTSHAEKVLQKLNLPYR
VMKLCTGDMSFSAKKTYDLEVWLPSQNTYREISSCSWCGDFQARRMKARHKNPSMKKPELVHTLNGSGLAVGRTLLAIIE
NYQQEDGSIMVPDALIKYMGGISVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-100 55