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Name : thyA (FTN_1248) Accession : YP_898883.1 Strain : Francisella novicida U112 Genome accession: NC_008601 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 1315576 - 1316400 bp Length : 825 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGCGAGAATATCTAAATTTCCTTAAGTATATCAAAGAAAATGGCGTTTTAAAGGGTGATAGAACCGGTACTGGAACAAG AAGTATCTTTGGCTATCAAATGCGTTTTGATCTTCAAAAAGGCTTCCCATTAGTAACTACAAAAAAAATTCATATTCCTA GTGTTGTTCATGAATTATTATGGTTTTTAAGTGGTAGTACAAATATCAAATATCTTAATGATAACAATGTTAGAATTTGG AATGAGTGGGCAACCGTAGATGGCGAACTTGGTCCTATTTATGGCAAGCAGTGGCGTGATTTTAACGGTCAAGGTATAGA TCAAATTGCCGATGTAATTCAGATGCTAAAAACAAACCCAAACTCACGTAGGATTCTAGTTTCAGCGTGGAATCCATGTG TTGTACCATCAGAAAAAATCTCTCCACAAGAAAATGTTGTAAAAGGTAATTCAGCCCTACCACCATGCCATGCAATGTTT CAGTTCTATGTGGCAAATAATAAACTATCATGCATGCTTACGCAAAGAAGTGCTGATGCTTTTCTTGGAGTACCATTTAA CATTGCAAGTTATTCACTACTGACACATATGGTTGCACAACAATGTAATCTTGATGTTGGTGAGTTCATCTGGTCAGGTG GTGATTGTCATATTTACAATAATCATATTGAGCAAGTCAATGAACAGCTTAGTCGTGAGCCTTTAGCTTTACCAACACTA AAGATTTTAAGAAAACCAAACTCCATCTTTGATTATAAATACGAAGATTTTGAATTTGAGAACTATAACCATCACCCTGC CATCAAAGCAAAAATATCTGTATAA Protein sequence : MREYLNFLKYIKENGVLKGDRTGTGTRSIFGYQMRFDLQKGFPLVTTKKIHIPSVVHELLWFLSGSTNIKYLNDNNVRIW NEWATVDGELGPIYGKQWRDFNGQGIDQIADVIQMLKTNPNSRRILVSAWNPCVVPSEKISPQENVVKGNSALPPCHAMF QFYVANNKLSCMLTQRSADAFLGVPFNIASYSLLTHMVAQQCNLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLALPTL KILRKPNSIFDYKYEDFEFENYNHHPAIKAKISV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 2e-74 | 59 |
| thyA | YP_189147.1 | thymidylate synthase | Not tested | ¥ÕSP¥â | Protein | 4e-48 | 45 |
