Gene Information

Name : leuS (BALH_4313)
Accession : YP_897022.1
Strain : Bacillus thuringiensis Al Hakam
Genome accession: NC_008600
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 4531481 - 4533889 bp
Length : 2409 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTTAATCATCAAGAAATTGAGAAGAAGTGGCAAGGGTACTGGGAAGAGAATAAAACATTCCGTACGCCAGATGA
GACAGAAAAACCAAAATTTTATGCACTAGATATGTTCCCATATCCATCAGGTGCAGGCCTACACGTAGGACATCCAGAAG
GTTATACAGCAACGGATATTTTATCTCGTATGAAGCGTATGCAAGGGTATAACGTTCTTCATCCAATGGGATGGGATGCA
TTCGGTCTTCCAGCAGAGCAATATGCACTTGATACTGGAAACAGCCCGGCTGAATTTACAGAGCATAATATTAATACGTT
CCGTAACCAAATTAAATCATTAGGTTTCTCTTATGATTGGGACCGTGAAGTAAATACAACAGATCCAAACTACTACAAGT
GGACACAATGGATCTTCCTGAAACTATTTGAAAAAGGCTTAGCTTATGTTGATGAAGTACCTGTAAACTGGTGCCCAGCA
CTTGGTACAGTACTTGCAAACGAAGAAATCATCGATGGTAAGAGTGAGCGCGGTGGACATCCAGTTGAGCGTCGTCCGAT
GAGACAGTGGATGTTAAAAATTACAGCATACGGAGATCGTCTATTGGAAGATCTAGATGAGCTTGATTGGCCAGAAAGTT
TAAAAGATATGCAACGTAACTGGATCGGTCGTTCTGAAGGTGCAGAAGTACACTTCAACATCGATGGTACAGACGAGAAG
TTCACAGTTTTCACAACGCGTCCTGATACACTATTTGGTGCAAGCTACTGTGTACTTGCTCCGGAACATGCGCTTGTTGC
TGACATTACAACTGCTGATCAAAAAGAAGCTGTAGAAGCTTACATTAATTCTGTAAAAATGAAGAGTGATCTAGAGCGTA
CAGAACTTGCGAAAGAGAAAACTGGTGTATTCACTGGTGCTTACGCAGTTAATCCAGTAAATGGTGAGAAATTACCAATC
TGGATCGCTGATTACGTTCTTGCAACTTACGGAACAGGTGCTGTAATGGCGGTTCCAGCTCACGATGAGCGTGACTATGA
ATTTGCATCAACGTTCAATCTTCCAATGAAGGAAGTTGTAAAAGGTGGAGATATTACGAAAGAAGCATACACAGGTGATG
GTGCTCACGTAAACTCAGCATTCCTTGATGGTTTAAATAAAGAAGAAGCAATCGCAAAAATGATTGAATGGCTTGAAGTA
ACGAGCGCAGGAAATCAAAAAGTAACATACCGTCTACGTGACTGGTTATTCAGCCGTCAACGTTACTGGGGTGAGCCAAT
TCCAGTAATTCACTGGGAAGATGGCACAATGACAGCTGTGAAAGAAGAAGAATTACCATTAGTTCTTCCGAAAACAGAAA
ACATCCGTCCTTCAGGTACAGGTGAATCACCACTTGCTAACATTGACGAGTGGGTAAATGTTGTTGATCCTGAGACTGGT
AAAAAAGGTCGTCGTGAAACAAATACAATGCCGCAATGGGCTGGTAGTTGCTGGTATTACCTACGTTACATCGATCCAAA
CAATAGCGAAGCACTTGTAGATCCTGAAAAAGTAAAACAATGGCTTCCAGTTGATATTTATATCGGTGGTGCAGAACACG
CTGTACTTCACTTACTGTATGCTCGTTTCTGGCATAAAGTATTATATGATATCGGTGTAGTTCCAACGAAAGAGCCGTTC
CAACAATTATTCAACCAAGGTATGATTCTAGGTGAAAACAACGAGAAAATGAGTAAATCAAAAGGTAACGTTGTAAACCC
TGATGATATCGTAGCGAGCCACGGTGCAGATACACTTCGTCTATACGAAATGTTCATGGGACCATTAGATGCTTCAATCG
CTTGGTCTGAAAATGGTCTTGACGGAGCTCGTCGTTTCCTAGACCGCGTATGGCGCCTATTCGTTCAAGATAACGGTGAA
TTAAGTGAGAAAATTACTGATGCACCAAATAAAGATCTTGAAAAAGCTTACCACCAAACAGTGAAGAAAGTAACAGAAGA
CTATGCAGAGCTTCGCTTCAACACAGCGATTTCTCAAATGATGGTATTCATCAACGATGCATACAAAGCTGAAACACTTC
CGAAAGAATATGTAGAAGGTTTCGTAAAAATGATTGCACCAGTTGCACCTCACATCGGGGAAGAACTATGGAGCAAACTT
GGATACAATGAAACAATCACATATGCAAGCTGGCCAACATTCGATGAGTCTAAACTTGTAGAAGATGAAGTTGAAATCGT
TGTTCAAGTTATGGGTAAAGTTCGCGCAAAACTAACAATGAGTAAAGACGCATCAAAAGACGAAATGGAAAAACTTGCAC
TTGAAGCAATTCAAGACCAAATCGAAGGGAAAACAGTTCGTAAAGTAATTGTTGTTCCTGGAAAACTTGTTAACGTTGTT
GCAAACTAA

Protein sequence :
MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPA
LGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEK
FTVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPI
WIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVKGGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEV
TSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETG
KKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPF
QQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGE
LSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPKEYVEGFVKMIAPVAPHIGEELWSKL
GYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKDEMEKLALEAIQDQIEGKTVRKVIVVPGKLVNVV
AN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67